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Results 1 to 25 of 65

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Novel oxazolo[4,5-g]quinazolin-2(1H)-ones: Dual inhibitors of EGFR and Src protein tyrosine kinasesJINSHENG LIN; WEI SHEN; JINGWEI XUE et al.European journal of medicinal chemistry. 2012, Vol 55, pp 39-48, issn 0223-5234, 10 p.Article

Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC-EGFR dual inhibitorsMIAO ZUO; ZHENG, Yue-Wen; LU, She-Min et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 14, pp 4405-4412, issn 0968-0896, 8 p.Article

Pharmacokinetic profile of cetuximab (Erbitux) alone and in combination with irinotecan in patients with advanced EGFR-positive adenocarcinomaDELBALDO, Catherine; PIERGA, Jean-Yves; RAYMOND, Eric et al.European journal of cancer (1990). 2005, Vol 41, Num 12, pp 1739-1745, issn 0959-8049, 7 p.Article

Antitumor Activity of Taspine by Modulating the EGFR Signaling Pathway of Erk1/2 and Akt In Vitro and In VivoYANMIN ZHANG; LEI ZHENG; JIE ZHANG et al.Planta medica. 2011, Vol 77, Num 16, pp 1774-1781, issn 0032-0943, 8 p.Article

Skin toxicities associated with epidermal growth factor receptor inhibitorsTIANHONG LI; PEREZ-SOLER, Roman.Targeted oncology. 2009, Vol 4, Num 2, pp 107-119, issn 1776-2596, 13 p.Article

Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumorsNAKAGAWA, K; TAMURA, T; FUKUOKA, M et al.Annals of oncology. 2003, Vol 14, Num 6, pp 922-930, issn 0923-7534, 9 p.Article

An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cellsYASHIRO, M; QIU, H; HASEGAWA, T et al.British journal of cancer. 2011, Vol 105, Num 10, pp 1522-1532, issn 0007-0920, 11 p.Article

BMS-6905 I4, a VEGFR and EGFR tyrosine kinase inhibitor, shows anti-tumoural activity on non-small-cell lung cancer xenografts and induces sequence-dependent synergistic effect with radiationLORIOT, Y; MORDANT, P; DORVAULT, N et al.British journal of cancer. 2010, Vol 103, Num 3, pp 347-353, issn 0007-0920, 7 p.Article

Synthesis and structure-activity relationship of 4-(2-aryl-cyclopropylamino)-quinoline-3-carbonitriles as EGFR tyrosine kinase inhibitorsPANNALA, Madhavi; KHER, Sunil; SAKURAI, Naoki et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 21, pp 5978-5982, issn 0960-894X, 5 p.Article

VeriStrat® has a prognostic value for patients with advanced non-small cell lung cancer treated with erlotinib and bevacizumab in the first line: Pooled analysis of SAKK19/05 and NTR528GAUTSCHI, Oliver; DINGEMANS, Anne-Marie; BATY, Florent et al.Lung cancer. 2013, Vol 79, Num 1, pp 59-64, issn 0169-5002, 6 p.Article

Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitorsYUNQI LI; CHUNYAN TAN; CHUNMEI GAO et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 15, pp 4529-4535, issn 0968-0896, 7 p.Article

In silico identification of novel EGFR inhibitors with antiproliferative activity against cancer cellsCAVASOTTO, Claudio N; ORTIZ, Maria A; ABAGYAN, Ruben A et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 7, pp 1969-1974, issn 0960-894X, 6 p.Article

Synthesis and antitumor evaluation of novel 5-substituted-4-hydroxy-8-nitroquinazolines as EGFR signaling-targeted inhibitorsYI JIN; LI, Hui-Yuan; LIN, Li-Ping et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 19, pp 5613-5622, issn 0968-0896, 10 p.Article

Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinomaKOBAYASHI, M; MIKI, Y; INOUE, A et al.British journal of cancer. 2012, Vol 107, Num 10, pp 1745-1753, issn 0007-0920, 9 p.Article

Novel EGFR inhibitors prepared by combination of dithiocarbamic acid esters and 4-anilinoquinazolinesLI, Ri-Dong; XIN ZHANG; LI, Qiao-Yan et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 12, pp 3637-3640, issn 0960-894X, 4 p.Article

Epidermal growth factor receptor inhibitors enhance susceptibility to Fas-mediated apoptosis in oral squamous cell carcinoma cellsIWASE, Masayasu; TAKAOKA, Sayaka; UCHIDA, Makiko et al.Oral oncology (1997). 2008, Vol 44, Num 4, pp 361-368, issn 1368-8375, 8 p.Article

In-Cell Western analysis of Helicobacter pylori-induced phosphorylation of extracellular-signal related kinase via the transactivation of the epidermal growth factor receptorYIQI DU; DANJO, Kazuma; ROBINSON, Philip A et al.Microbes and infection. 2007, Vol 9, Num 7, pp 838-846, issn 1286-4579, 9 p.Article

Synthesis and biological evaluation of crown ether fused quinazoline analogues as potent EGFR inhibitorsSHAOJING HU; GUOJIAN XIE; YINXIANG WANG et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 19, pp 6301-6305, issn 0960-894X, 5 p.Article

(Arene)Ru(II) complexes of epidermal growth factor receptor inhibiting tyrphostins with enhanced selectivity and cytotoxicity in cancer cellsBIERSACK, B; ZOLDAKOVA, M; EFFENBERGER, K et al.European journal of medicinal chemistry. 2010, Vol 45, Num 5, pp 1972-1975, issn 0223-5234, 4 p.Article

Radiosensitivity of prostate cancer cells is enhanced by EGFR inhibitor C225FENG LIU; WANG, Jun-Jie; YOU, Zhen-Yu et al.Urologic oncology. 2010, Vol 28, Num 1, pp 59-66, issn 1078-1439, 8 p.Article

Acute and fatal diarrhoea after erlotinib plus abdominal palliative hypofractionated radiotherapy in a metastatic non-small cell lung cancer patient : A case reportSILVANO, Giovanni; LAZZARI, Grazia; LOVECCHIO, Monica et al.Lung cancer. 2008, Vol 61, Num 2, pp 270-273, issn 0169-5002, 4 p.Article

Comparison of the epidermal growth factor receptor gene and protein in primary non-small-cell-lung cancer and metastatic sites : implications for treatment with EGFR-inhibitorsITALIANO, A; BUREL VANDENBOS, F; OTTO, J et al.Annals of oncology. 2006, Vol 17, Num 6, pp 981-985, issn 0923-7534, 5 p.Article

Topical therapy with nadifloxacin cream and prednicarbate cream improves acneiform eruptions caused by the EGFR-inhibitor cetuximab ― A report of 29 patientsKATZER, Kerstin; TIETZE, Julia; KLEIN, Elisabeth et al.EJD. European journal of dermatology. 2010, Vol 20, Num 1, pp 82-84, issn 1167-1122, 3 p.Article

DUSP6 regulates drug sensitivity by modulating DNA damage responseBAGNYUKOVA, T. V; RESTIFO, D; BEEHARRY, N et al.British journal of cancer. 2013, Vol 109, Num 4, pp 1063-1071, issn 0007-0920, 9 p.Article

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugsGELARDI, T; CAPUTO, R; DAMIANO, V et al.British journal of cancer. 2008, Vol 99, Num 3, pp 473-480, issn 0007-0920, 8 p.Article

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