Activation of α-diacylglycerol kinase is critical for the mitogenic properties of anaplastic lymphoma kinase. CommentaryBACCHIOCCHI, Roberta; BALDANZI, Gianluca; CARBONARI, Damiano et al.Blood. 2005, Vol 106, Num 6, pp 1894-1895, issn 0006-4971, 10 p.Article

Serine phosphorylation of NPM―ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potentialPENG WANG; FANG WU; JINGDONG ZHANG et al.Carcinogenesis (New York. Print). 2011, Vol 32, Num 2, pp 146-153, issn 0143-3334, 8 p.Article

Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOSQIAN ZHANG; HONGYI WANG; MARAFIOTI, Teresa et al.Blood. 2011, Vol 118, Num 11, pp 3062-3071, issn 0006-4971, 10 p.Article

Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastosytosisKANEGANE, Hirokazu; NOMURA, Keiko; ABE, Akihiro et al.International journal of hematology. 2009, Vol 89, Num 1, pp 86-90, issn 0925-5710, 5 p.Article

Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC) : Overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1CHANG, Joseph T; WANG, Hung-Ming; CHENG, Ann-Joy et al.International journal of cancer. 2005, Vol 114, Num 6, pp 942-949, issn 0020-7136, 8 p.Article

Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosminQUENTMEIER, H; MARTELLI, M. P; MARTELLI, M. F et al.Leukemia. 2005, Vol 19, Num 10, pp 1760-1767, issn 0887-6924, 8 p.Article

The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathwayMARTINELLI, Paola; BONETTI, Paola; KHORAMIAN TUSI, Betsabeh et al.Blood. 2011, Vol 117, Num 24, pp 6617-6626, issn 0006-4971, 10 p.Article

Detection of the t(2;5)-associated NPM/ALK fusion cDNA in peripheral blood cells of healthy individualsTRÜMPER, L; PFREUNDSCHUH, M; BONIN, F. V et al.British journal of haematology. 1998, Vol 103, Num 4, pp 1138-1144, issn 0007-1048Article

NPM-ALK Oncogenic Tyrosine Kinase Controls T-Cell Identity by Transcriptional Regulation and Epigenetic Silencing in Lymphoma CellsAMBROGIO, Chiara; MARTINENGO, Cinzia; VOENA, Claudia et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 22, pp 8611-8619, issn 0008-5472, 9 p.Article

A liaison dangereuse between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK. CommentaryMORRIS, Stephan W; FAWAL, Mohamad; ARMSTRONG, Florence et al.Blood. 2006, Vol 108, Num 8, issn 0006-4971, 2500-2501,2780-2788 [11 p.]Article

Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK⁺ anaplastic large-cell lymphoma. CommentaryMORRIS, Stephan W; YAJUN HAN; AMIN, Hesham M et al.Blood. 2006, Vol 108, Num 8, issn 0006-4971, 2500-2501,2796-2803 [10 p.]Article

What have we learnt from mouse models of NPM-ALK-induced lymphomagenesis?TURNER, S. D; ALEXANDER, D. R.Leukemia. 2005, Vol 19, Num 7, pp 1128-1134, issn 0887-6924, 7 p.Article

NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3aGU, Ting-Lei; TOTHOVA, Zuzana; SCHEIJEN, Blanca et al.Blood. 2004, Vol 103, Num 12, pp 4622-4629, issn 0006-4971, 8 p.Article

Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemiaGIURIATO, Sylvie; FOISSEAU, Marianne; MEGGETTO, Fabienne et al.Blood. 2010, Vol 115, Num 20, pp 4061-4070, issn 0006-4971, 10 p.Article

The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activityBONVINI, Paolo; ZORZI, Elisa; MUSSOLIN, Lara et al.Haematologica (Roma). 2009, Vol 94, Num 7, pp 944-955, issn 0390-6078, 12 p.Article

The tyrosine phosphatase shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migrationVOENA, Claudia; CONTE, Chiara; AMBROGIO, Chiara et al.Cancer research (Baltimore). 2007, Vol 67, Num 9, pp 4278-4286, issn 0008-5472, 9 p.Article

Fusion tyrosine kinase mediated signalling pathways in the transformation of haematopoietic cellsTURNER, S. D; ALEXANDER, D. R.Leukemia. 2006, Vol 20, Num 4, pp 572-582, issn 0887-6924, 11 p.Article

ALK-positive plasmablastic B-cell lymphoma with expression of the NPM-ALK fusion transcript: report of 2 casesONCIU, Mihaela; BEHM, Frederick G; DOWNING, James R et al.Blood. 2003, Vol 102, Num 7, pp 2642-2644, issn 0006-4971, 3 p.Article

Consequences of heat shock protein 72 (Hsp72) expression and activity on stress-induced apoptosis in CD30⁺ NPM―ALK⁺ anaplastic large-cell lymphomasBONVINI, P; ZORZI, E; MUSSOLIN, L et al.Leukemia. 2012, Vol 26, Num 6, pp 1375-1382, issn 0887-6924, 8 p.Article

Cutaneous presentation of ALK-positive anaplastic large cell lymphoma following insect bites: evidence for an association in five casesLAMANT, Laurence; PILERI, Stefano; SABATTINI, Elena et al.Haematologica (Roma). 2010, Vol 95, Num 3, pp 449-455, issn 0390-6078, 7 p.Article

Distribution of NPM1-ALK and X-ALK fusion transcripts in paediatric anaplastic large cell lymphoma: a molecular-histological correlationDAMM-WELK, Christine; KLAPPER, Wolfram; OSCHLIES, Ilske et al.British journal of haematology. 2009, Vol 146, Num 3, pp 306-309, issn 0007-1048, 4 p.Article

NPM-ALK-dependent expression of the transcription factor CCΑΑT/enhancer binding protein β in ALK-positive anaplastic large cell lymphomaQUINTANILLA-MARTINEZ, Leticia; PITTALUGA, Stefania; JAFFE, Elaine S et al.Blood. 2006, Vol 108, Num 6, pp 2029-2036, issn 0006-4971, 8 p.Article

Mice transgenic for NPM-ALK develop non-hodgkin lymphomasJÄGER, Richard; HAHNE, Jens; JACOB, Andrea et al.Anticancer research. 2005, Vol 25, Num 5, pp 3191-3196, issn 0250-7005, 6 p.Article

Bcl-X_L down-regulation suppresses the tumorigenic potential of NPM/ALK in vitro and in vivoCOLUCCIA, Addolorata Maria; PEREGO, Silvia; CLERIS, Loredana et al.Blood. 2004, Vol 103, Num 7, pp 2787-2794, issn 0006-4971, 8 p.Article

Selective inhibition of STAT3 induces apoptosis and G₁ cell cycle arrest in ALK-positive anaplastic large cell lymphomaAMIN, Hesham M; MCDONNELL, Timothy J; MEDEIROS, L. Jeffrey et al.Oncogene (Basingstoke). 2004, Vol 23, Num 32, pp 5426-5434, issn 0950-9232, 9 p.Article