Heat shock proteins as emerging therapeutic targetsSOTI, Csaba; NAGY, Eniko; GIRICZ, Zoltan et al.British journal of pharmacology. 2005, Vol 146, Num 6, pp 769-780, issn 0007-1188, 12 p.Article

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Heat shock protein 90 inhibitors. A text book example of medicinal chemistry?JANIN, Yves L.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 24, pp 7503-7512, issn 0022-2623, 10 p.Article

Synthesis of Reblastatin, Autolytimycin, and Non-Benzoquinone Analogues: Potent Inhibitors of Heat Shock Protein 90WRONA, Iwona E; GOZMAN, Alexander; TALDONE, Tony et al.Journal of organic chemistry. 2010, Vol 75, Num 9, pp 2820-2835, issn 0022-3263, 16 p.Article

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Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl-amine linker systemBURKE, Patrick J; TOKI, Brian E; MEYER, David W et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 10, pp 2650-2653, issn 0960-894X, 4 p.Article

Synthesis and biological activities of novel 17-aminogeldanamycin derivativesTIAN, Zong-Qiang; YAOQUAN LIU; DAN ZHANG et al.Bioorganic & medicinal chemistry. 2004, Vol 12, Num 20, pp 5317-5329, issn 0968-0896, 13 p.Article

Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to taxolSOLIT, David B; BASSO, Andrea D; OLSHEN, Adam B et al.Cancer research (Baltimore). 2003, Vol 63, Num 9, pp 2139-2144, issn 0008-5472, 6 p.Article

LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related familyCHIOSIS, Gabriela; ROSEN, Neal; SEPP-LORENZINO, Laura et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 7, pp 909-913, issn 0960-894XArticle

GROWTH INHIBITION OF VIRUS TRANSFORMED CELLS IN VITRO AND ANTITUMOR ACTIVITY IN VIVO OF GELDANAMYCIN AND ITS DERIVATIVESSASAKI K; YASUDA H; ONODERA K et al.1979; J. ANTIBIOT.; JPN; DA. 1979; VOL. 32; PP. 849-851; BIBL. 10 REF.Article

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Improved synthesis and evaluation of 17-substituted aminoalkylgeldanamycin derivatives applicable to drug delivery systemsKASUYA, Yuji; LU, Zheng-Rong; KOPECKOVA, Pavla et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 16, pp 2089-2091, issn 0960-894XArticle

Synthesis and evaluation of geldanamycin-testosterone hybridsKUDUK, S. D; HARRIS, C. R; ZHENG, F. F et al.Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 11, pp 1303-1306, issn 0960-894XArticle

Cancer Therapeutic Agents Targeting Hypoxia-Inducible Factor-1WANG, R; ZHOU, S; LI, S et al.Current medicinal chemistry. 2011, Vol 18, Num 21, pp 3168-3189, issn 0929-8673, 22 p.Article

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Design, synthesis, and structure - : Activity relationships for chimeric inhibitors of Hsp90GANG SHEN; MINGWEN WANG; WELCH, Timothy R et al.Journal of organic chemistry. 2006, Vol 71, Num 20, pp 7618-7631, issn 0022-3263, 14 p.Article

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