Synthesis of constrained benzocinnolinone analogues of CEP-26401 (irdabisant) as potent, selective histamine H₃ receptor inverse agonistsJOSEF, Kurt A; AIMONE, Lisa D; LYONS, Jacquelyn et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4198-4202, issn 0960-894X, 5 p.Article

The Efficacy and Tolerability of Two Novel H₁/H₃ Receptor Antagonists in Seasonal Allergic RhinitisDALEY-YATES, Peter; AMBERY, Claire; SWEENEY, Lisa et al.International archives of allergy and immunology. 2012, Vol 158, Num 1, pp 84-98, issn 1018-2438, 15 p.Article

The histamine H₃ receptor : an attractive target for the treatment of cognitive disordersESBENSHADE, T. A; BROWMAN, K. E; BITNER, R. S et al.British journal of pharmacology. 2008, Vol 154, Num 6, pp 1166-1181, issn 0007-1188, 16 p.Article

A novel class of H₃ antagonists derived from the natural product guided synthesis of unnatural analogs of the marine bromopyrrole alkaloid dispyrinKENNEDY, J. Phillip; CONN, P. Jeffrey; LINDSLEY, Craig W et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 12, pp 3204-3208, issn 0960-894X, 5 p.Article

Pruritus-associated response mediated by cutaneous histamine H₃ receptorsSUGIMOTO, Y; IBA, Y; NAKAMURA, Y et al.Clinical and experimental allergy (Print). 2004, Vol 34, Num 3, pp 456-459, issn 0954-7894, 4 p.Article

Nasal allergic response mediated by histamine H₃ receptors in murine allergic rhinitisNAKAYA, Muneo; FUKUSHIMA, Yasushi; TAKEUCHI, Naonobu et al.The Laryngoscope. 2005, Vol 115, Num 10, pp 1778-1784, issn 0023-852X, 7 p.Article

Identification of biaryl sulfone derivatives as antagonists of the histamine H₃ receptor: Discovery of (R)-1-2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl-2-methylpyrrolidine (APD916)SEMPLE, Graeme; SANTORA, Vincent J; HOFILENA, Brian J et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 1, pp 71-75, issn 0960-894X, 5 p.Article

Synthesis and structure―activity relationship (SAR) study of 4-azabenzoxazole analogues as H₃ antagonistsNING SHAO; ASLANIAN, Robert; WEST, Robert E et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 5, pp 2075-2078, issn 0960-894X, 4 p.Article

Fused bicycles as arylketone bioisosteres leading to potent, orally active thiadiazole H3 antagonistsDONG XIAO; PALANI, Anandan; KORFMACHER, Walter A et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 9, pp 3354-3357, issn 0960-894X, 4 p.Article

Involvement of histamine H₃ receptors in scratching behaviour in mast cell-deficient miceHOSSEN, M. A; SUGIMOTO, Y; KAYASUGA, R et al.British journal of dermatology (1951). 2003, Vol 149, Num 1, pp 17-22, issn 0007-0963, 6 p.Article

Synthesis and structure-activity relationships for biphenyl H₃ receptor antagonists with moderate anti-cholinesterase activityMORINI, Giovanni; COMINI, Mara; BAROCELLI, Elisabetta et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 23, pp 9911-9924, issn 0968-0896, 14 p.Article

Intracerebroventricular administration of histamine H₃ receptor antagonists decreases seizures in rat models of epilepsiaHARADA, C; HIRAI, T; FUJII, Y et al.Methods and findings in experimental and clinical pharmacology. 2004, Vol 26, Num 4, pp 263-270, issn 0379-0355, 8 p.Article

Reversal of Oxidative Stress by Histamine H₃ Receptor-Ligands in Experimental Models of SchizophreniaMAHMOOD, D; KHANAM, R; PILLAI, K. K et al.Arzneimittel-Forschung. 2012, Vol 62, Num 5, pp 222-229, issn 0004-4172, 8 p.Article

Imidazole H₃-antagonists: relationship between structure and ex vivo binding to rat brain H₃-receptorsVACONDIO, Federica; MOR, Marco; BALLABENI, Vigilio et al.European journal of pharmaceutical sciences. 2004, Vol 23, Num 1, pp 89-98, issn 0928-0987, 10 p.Article

The effect of betahistine, a histamine H₁ receptor agonist/H₃ antagonist, on olanzapine-induced weight gain in first-episode schizophrenia patientsPOYUROVSKY, Michael; PASHINIAN, Artashes; LEVI, Aya et al.International clinical psychopharmacology. 2005, Vol 20, Num 2, pp 101-103, issn 0268-1315, 3 p.Article

The synthesis and structure-activity relationship of 4-benzimidazolyl-piperidinylcarbonyl-piperidine analogs as histamine H₃ antagonistsTING, Pauline C; LEE, Joe F; ANTHES, John C et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 17, pp 5004-5008, issn 0960-894X, 5 p.Article

Novel H₃ receptor antagonists with improved pharmacokinetic profilesSANTORA, Vincent J; COVEL, Jonathan A; EDWARDS, Jeffrey E et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 4133-4136, issn 0960-894X, 4 p.Article

H₃ receptor ligands: new imidazole H₃-antagonists endowed with NO-donor propertiesBERTINARIA, Massimo.Il Farmaco (Pavia). 2003, Vol 58, Num 3, pp 279-283, issn 0014-827X, 5 p.Conference Paper

Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chainBORDI, Fabrizio; RIVARA, Silvia; BAROCELLI, Elisabetta et al.European journal of medicinal chemistry. 2012, Vol 48, pp 214-230, issn 0223-5234, 17 p.Article

Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonistsBERLIN, Michael; YOON JOO LEE; BOYCE, Christopher W et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 7, pp 2359-2364, issn 0960-894X, 6 p.Article

Development and validation of a LC-MS method with electrospray ionization for the determination of the imidazole H₃ antagonist ROS203 in rat plasmaVACONDIO, Federica; SILVA, Claudia; FIONI, Alessandro et al.Journal of pharmaceutical and biomedical analysis. 2008, Vol 46, Num 1, pp 200-205, issn 0731-7085, 6 p.Article

Novel naphthyridines are histamine H₃ antagonists and serotonin reuptake transporter inhibitorsLETAVIC, Michael A; KEITH, John M; LY, Kiev S et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 9, pp 2566-2569, issn 0960-894X, 4 p.Article

The effects of thioperamide on extracellular levels of glutamate and GABA in the rat prefrontal cortexWELTY, Natalie; SHOBLOCK, James R.Psychopharmacologia. 2009, Vol 207, Num 3, pp 433-438, issn 0033-3158, 6 p.Article

Non-imidazole histamine H₃ ligands, Part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivativesFRYMARKIEWICZ, Anna; WALCZYNSKI, Krzysztof.European journal of medicinal chemistry. 2009, Vol 44, Num 4, pp 1674-1681, issn 0223-5234, 8 p.Article

Synthesis and evaluation of pyridone-phenoxypropyl-R-2-methylpyrrolidine analogues as histamine H₃ receptor antagonistsBECKNELL, Nadine C; LYONS, Jacquelyn A; AIMONE, Lisa D et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 23, pp 7076-7080, issn 0960-894X, 5 p.Article