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RDEA119/BAY 869766: A Potent, Selective, Allosteric Inhibitor of MEK1/2 for the Treatment of CancerIVERSON, Cory; LARSON, Gary; HAMATAKE, Robert et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 17, pp 6839-6847, issn 0008-5472, 9 p.Article

Fused thiophene derivatives as MEK inhibitorsLAING, Victoria E; BROOKINGS, Daniel C; MEIER, Christoph et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 1, pp 472-475, issn 0960-894X, 4 p.Article

Matrix metalloproteinase inhibitors : New challenges in the era of post broad-spectrum inhibitorsNUTI, Elisa; TUCCINARDI, Tiziano; ROSSELLO, Armando et al.Current pharmaceutical design. 2007, Vol 13, Num 20, pp 2087-2100, issn 1381-6128, 14 p.Article

Phosphoenolpyruvate-insensitive phosphofructokinase isozyme from Thermus thermophilus HB8JING XU; OSHIMA, T; YOSHIDA, M et al.Journal of biochemistry (Tokyo). 1991, Vol 109, Num 2, pp 199-203, issn 0021-924X, 5 p.Article

Inhibition of hepatic tryptophan-2,3-dioxygenase : Superior potency of melatonin over serotoninWALSH, H. A; DAYA, S.Journal of pineal research. 1997, Vol 23, Num 1, pp 20-23, issn 0742-3098Article

Enhanced oxygenation in vivo by allosteric inhibitors of hemoglobin saturationKHANDELWAL, S. R; RANDAD, R. S; PECK-SUN LIN et al.American journal of physiology. Heart and circulatory physiology. 1993, Vol 34, Num 4, pp H1450-H1453, issn 0363-6135Article

Characterization of pyridoxal 5'-phosphate affinity labeling of band 3 protein: evidence for allosterically interacting transport inhibitory subdomainsSALHANY, J. M; RAUENBUEHLER, P. B; SLOAN, R. L et al.The Journal of biological chemistry (Print). 1987, Vol 262, Num 33, pp 15965-15973, issn 0021-9258Article

Insights into MAPK p38α DFG flip mechanism by accelerated molecular dynamicsFILOMIA, Federico; DE RIENZO, Francesca; MENZIANI, M. Cristina et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 18, pp 6805-6812, issn 0968-0896, 8 p.Article

A conformational transition involved in antagonistic substrate binding to the allosteric phosphofructokinase from Escherichia coliDEVILLE-BONNE, D; GAREL, J.-R.Biochemistry (Easton). 1992, Vol 31, Num 6, pp 1695-1700, issn 0006-2960Article

Preclinical Characterization of BMS-791325, an Allosteric Inhibitor of Hepatitis C Virus NS5B PolymeraseLEMM, Julie A; MENGPING LIU; KNIPE, Jay O et al.Antimicrobial agents and chemotherapy. 2014, Vol 58, Num 6, pp 3485-3495, issn 0066-4804, 11 p.Article

Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitorBERTINI, R; BARCELOS, L. S; CORSI, M. M et al.British journal of pharmacology. 2012, Vol 165, Num 2, pp 436-454, issn 0007-1188, 19 p.Article

New Directions in Targeting Protein Kinases: Focusing Upon True Allosteric and Bivalent InhibitorsLAMBA, Vandana; GHOSH, Indraneel.Current pharmaceutical design (Print). 2012, Vol 18, Num 20, pp 2936-2945, issn 1381-6128, 10 p.Article

Phosphorylase a is an allosteric inhibitor of the glycogen and microsomal forms of rat hepatic protein phosphatase-1ALEMANY, S; COHEN, P.FEBS letters. 1986, Vol 198, Num 2, pp 194-202, issn 0014-5793Article

A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixturesANNIS, D. Allen; NAZEF, Naim; CHUANG, Cheng-Chi et al.Journal of the American Chemical Society. 2004, Vol 126, Num 47, pp 15495-15503, issn 0002-7863, 9 p.Article

The role of Glu187 in the regulation of phosphofructokinase by phosphoenolpyruvateAUZAT, I; LE BRAS, G; BRANNY, P et al.Journal of molecular biology. 1994, Vol 235, Num 1, pp 68-72, issn 0022-2836Article

Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase bJOHNSON, L. N; SNAPE, P; MARTIN, J. L et al.Journal of molecular biology. 1993, Vol 232, Num 1, pp 253-267, issn 0022-2836Article

Substituted Terphenyl Compounds as the First Class of Low Molecular Weight Allosteric Inhibitors of the Luteinizing Hormone ReceptorHEITMAN, Laura H; NARLAWAR, Rajeshwar; DE VRIES, Henk et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 7, pp 2036-2042, issn 0022-2623, 7 p.Article

Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF ActivityISHII, Nobuya; HARADA, Naoki; AOKI, Toshihiro et al.Cancer research (Chicago, Ill.). 2013, Vol 73, Num 13, pp 4050-4060, issn 0008-5472, 11 p.Article

Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysisFORD, Nathan; CALMY, Alexandra; MOFENSON, Lynne et al.AIDS (London). 2011, Vol 25, Num 18, pp 2301-2304, issn 0269-9370, 4 p.Article

Clinical interaction between efavirenz and phenytoinSPAK, Cedric W; DHANIREDDY, Shireesha; KOSEL, Bradley W et al.AIDS (London). 2008, Vol 22, Num 1, pp 164-165, issn 0269-9370, 2 p.Article

Efavirenz : innocent bystander or direct nephrotoxin?WYATT, Christina M; RODRIGUEZ-CAPRIO, Gabriela; KLOTMAN, Paul E et al.AIDS (London). 2007, Vol 21, Num 10, issn 0269-9370, 1393Article

Psychotrine and its O-methyl ether are selective inhibitors of human immunodeficiency virus-1 reverse transcriptaseTAN, G. T; KINGHORN, A. D; HUGHES, S. H et al.The Journal of biological chemistry (Print). 1991, Vol 266, Num 35, pp 23529-23536, issn 0021-9258Article

Compromising Mitochondrial Function with the Antiretroviral Drug Efavirenz Induces Cell Survival-Promoting AutophagyAPOSTOLOVA, Nadezda; GOMEZ-SUCERQUIA, Leysa J; GORTAT, Anna et al.Hepatology (Baltimore, Md.). 2011, Vol 54, Num 3, pp 1009-1019, issn 0270-9139, 11 p.Article

5'-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylaseCASANOVA, Elena; HERNANDEZ, Ana-Isabel; PRIEGO, Eva-Maria et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 18, pp 5562-5570, issn 0022-2623, 9 p.Article

Kinetic studies of lysine-sensitive aspartate kinase purified from maize suspension culturesDOTSON, S. B; SOMERS, D. A; GENGENBACH, B. G et al.Plant physiology (Bethesda). 1990, Vol 93, Num 1, pp 98-104, issn 0032-0889, 7 p.Article

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