Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002GUPTA, Anjali K; CERNIGLIA, George J; MICK, Rosemarie et al.International journal of radiation oncology, biology, physics. 2003, Vol 56, Num 3, pp 846-853, issn 0360-3016, 8 p.Conference Paper

The Phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 modulates cytokine expression in macrophages via p50 nuclear factor kappa B inhibition, in a PI3K-independent mechanismAVNI, Dorit; GLUCKSAM, Yifat; ZOR, Tsaffrir et al.Biochemical pharmacology. 2012, Vol 83, Num 1, pp 106-114, issn 0006-2952, 9 p.Article

Role of NF-KB and PI 3-kinase/Akt in TNF-α-induced cytotoxicity in microvascular endothelial cellsZHU ZHOU; GENGARO, Patricia; WEI WANG et al.American journal of physiology. Renal physiology. 2008, Vol 64, Num 4, issn 1931-857X, F932-F941Article

The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1ABDUL-GHANI, R; SERRA, V; GYÖRFFY, B et al.Oncogene (Basingstoke). 2006, Vol 25, Num 12, pp 1743-1752, issn 0950-9232, 10 p.Article

14-3-3γ is upregulated by in vitro ischemia and binds to protein kinase Raf in primary cultures of astrocytesXIAO QIAN CHEN; JIAN GUO CHEN; YUN ZHANG et al.Glia (New York, NY. Print). 2003, Vol 42, Num 4, pp 315-324, issn 0894-1491, 10 p.Article

Inhibitory actions of the phosphatidylinositol 3-kinase inhibitor LY294002 on the human Kv1.5 channelWU, J; DING, W.-G; MATSUURA, H et al.British journal of pharmacology. 2009, Vol 156, Num 2, pp 377-387, issn 0007-1188, 11 p.Article

Dual modulation of JNK and Akt signaling pathways by chaetoglobosin K in human lung carcinoma and ras-transformed epithelial cellsALI, Amna; SIDOROVA, Tatyana S; MATESIC, Diane F et al.Investigational new drugs. 2013, Vol 31, Num 3, pp 525-534, issn 0167-6997, 10 p.Article

A novel diffusion cell model for the in vitro assessment of transcutaneous breast cancer therapeutics: Effect of permeants on MCF-7 cells cultured within the receptor compartmentDAVISON, Zoë; NICHOLSON, Robert I; DENYER, Stephen P et al.European journal of pharmaceutics and biopharmaceutics. 2010, Vol 75, Num 3, pp 411-417, issn 0939-6411, 7 p.Article

Early growth response-1 induction by fibroblast growth factor-1 via increase of mitogen-activated protein kinase and inhibition of protein kinase B in hippocampal neuronsBENZ, Alexander H; SHAJARI, Mehdi; PERUZKI, Natalie et al.British journal of pharmacology. 2010, Vol 160, Num 7, pp 1621-1630, issn 0007-1188, 10 p.Article

Inhibition of phosphatidylinositol 3-kinase causes cell death in rat osteoblasts through inactivation of AktYUN ZHANG; LE ZHANG; MING YAN et al.Biomedicine & pharmacotherapy. 2007, Vol 61, Num 5, pp 277-284, issn 0753-3322, 8 p.Article

Phosphoinositide-3-OH-kinase inhibitor LY294002 prevents activation of Ancylostoma caninum and Ancylostoma ceylanicum third-stage infective larvaeBRAND, Andrea; HAWDON, John M.International journal for parasitology. 2004, Vol 34, Num 8, pp 909-914, issn 0020-7519, 6 p.Article

Growth inhibition of human malignant glioma cells induced by the PI3-K-specific inhibitorSHINGU, Takashi; YAMADA, Kazuo; HARA, Nobumasa et al.Journal of neurosurgery. 2003, Vol 98, Num 1, pp 154-161, issn 0022-3085, 8 p.Article

PTEN activation sensitizes breast cancer to PI3-kinase inhibitor through the β-catenin signaling pathwayYU REN; XUAN ZHOU; YANBIN QI et al.Oncology reports. 2012, Vol 28, Num 3, pp 943-948, issn 1021-335X, 6 p.Article

Study of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neuronsVAZQUEZ DE LA TORRE, Aurelio; JUNYENT, Felix; FOLCH, Jaume et al.Neurochemistry international. 2011, Vol 59, Num 2, pp 159-167, issn 0197-0186, 9 p.Article

LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cellsOHNISHI, Ken; YASUMOTO, Jun-Ichi; TAKAHASHI, Akihisa et al.International journal of oncology. 2006, Vol 29, Num 1, pp 249-253, issn 1019-6439, 5 p.Article

LY294002 and rapamycin co-operate to inhibit T-cell proliferationBRESLIN, Elaine M; WHITE, Paul C; SHORE, Angharad M et al.British journal of pharmacology. 2005, Vol 144, Num 6, pp 791-800, issn 0007-1188, 10 p.Article

RNA interference against a glioma-derived allele of EGFR induces blockade at G₂MFAN, Qi-Wen; WEISS, William A.Oncogene (Basingstoke). 2005, Vol 24, Num 5, pp 829-837, issn 0950-9232, 9 p.Article

VEGF-mediated survivin expression in neuroblastoma cellsBEIERLE, Elizabeth A; NAGARAM, Abhilasha; WEI DAI et al.The Journal of surgical research. 2005, Vol 127, Num 1, pp 21-28, issn 0022-4804, 8 p.Article

Insulin-like growth factor signaling pathway involved in regulating longevity of rotifersYOSHINAGA, Tatsuki; KANEKO, Gen; KINOSHITA, Shigeharu et al.Hydrobiologia (The Hague). 2005, Vol 546, pp 347-352, issn 0018-8158, 6 p.Conference Paper

LY294002, an inhibitor of phosphatidylinositol-3-kinase, causes preferential induction of apoptosis in human multidrug resistant cellsNICHOLSON, K. M; QUINN, D. M; KELLETT, G. L et al.Cancer letters. 2003, Vol 190, Num 1, pp 31-36, issn 0304-3835, 6 p.Article

Phosphatidylinositol 3-kinase inhibitor failed to reduce cerebral vasospasm in dog model of experimental subarachnoid hemorrhageKIMURA, Hitoshi; SASAKI, Kenroh; MEGURO, Toshinari et al.Stroke (1970). 2002, Vol 33, Num 2, pp 593-599, issn 0039-2499Article

The PI3K/Akt inhibitor LY294002 reverses BCRP-mediated drug resistance without affecting BCRP translocationIMAI, Yasuo; YOSHIMORI, Mayumi; FUKUDA, Kazunori et al.Oncology reports. 2012, Vol 27, Num 6, pp 1703-1709, issn 1021-335X, 7 p.Article

LY294002 Enhances Boswellic Acid-induced Apoptosis in Colon Cancer CellsLIU, Jian-Jun; DUAN, Rui-Dong.Anticancer research. 2009, Vol 29, Num 8, pp 2987-2991, issn 0250-7005, 5 p.Article

Simultaneous blockade of AP-I and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cellsKIKUCHI, J; KINOSHITA, I; SHIMIZU, Y et al.British journal of cancer. 2008, Vol 99, Num 12, pp 2013-2019, issn 0007-0920, 7 p.Article

Mechanisms of tissue inhibitor of metalloproteinase 1 augmentation by IL-13 on TGF-β1-stimulated primary human fibroblastsXIUXIA ZHOU; HAIZHEN HU; HUYNH, Mai-Lan N et al.Journal of allergy and clinical immunology. 2007, Vol 119, Num 6, pp 1388-1397, issn 0091-6749, 10 p.Article