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Inhibitor of apoptosis protein (IAP) survivin is upregulated by oncogenic c-H-RasSOMMER, Klaus W; SCHAMBERGER, Chantal J; SCHMIDT, Gerlinde E et al.Oncogene (Basingstoke). 2003, Vol 22, Num 27, pp 4266-4280, issn 0950-9232, 15 p.Article

MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosisLUNGHI, Paolo; COSTANZO, Antonio; SALVATORE, Luigi et al.Blood. 2006, Vol 107, Num 11, pp 4549-4553, issn 0006-4971, 5 p.Article

Scaffolding actions of membrane-associated progesterone receptorsHAGAN, Christy R; FAIVRE, Emily J; LANGE, Carol A et al.Steroids. 2009, Vol 74, Num 7, pp 568-572, issn 0039-128X, 5 p.Conference Paper

A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexesGLOECKNER, Christian Johannes; BOLDT, Karsten; SCHUMACHER, Annette et al.Proteomics (Weinheim. Print). 2007, Vol 7, Num 23, pp 4228-4234, issn 1615-9853, 7 p.Article

MEK1-induced Golgi dynamics during cell cycle progression is partly mediated by Polo-like kinase-3SUQING XIE; QI WANG; QIN RUAN et al.Oncogene (Basingstoke). 2004, Vol 23, Num 21, pp 3822-3829, issn 0950-9232, 8 p.Article

DNA double-strand breaks in meiosis: Checking their formation, processing and repairPIA LONGHESE, Maria; BONETTI, Diego; GUERINI, Ilaria et al.DNA repair. 2009, Vol 8, Num 9, pp 1127-1138, issn 1568-7864, 12 p.Article

Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cellsLUNGHI, P; TABILIO, A; LO-COCO, F et al.Leukemia. 2005, Vol 19, Num 2, pp 234-244, issn 0887-6924, 11 p.Article

Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylationWEIDONG HUANG; ALESSANDRINI, A; CREWS, C. M et al.Proceedings of the National Academy of Sciences of the United States of America. 1993, Vol 90, Num 23, pp 10947-10951, issn 0027-8424Article

Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosisPIA LONGHESE, Maria; GUERINI, Ilaria; BALDO, Veronica et al.DNA repair. 2008, Vol 7, Num 4, pp 545-557, issn 1568-7864, 13 p.Article

Expanding the Genetic Code of Escherichia coli with PhosphoserinePARK, Hee-Sung; HOHN, Michael ]; UMEHARA, Takuya et al.Science (Washington, D.C.). 2011, Vol 333, Num 6046, pp 1151-1154, issn 0036-8075, 4 p.Article

B-Raf and C-Raf are required for Ras-stimulated p42 MAP kinase activation in Xenopus egg extractsYUE, J; XIONG, W; FERRELL, J. E et al.Oncogene (Basingstoke). 2006, Vol 25, Num 23, pp 3307-3315, issn 0950-9232, 9 p.Article

Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino- isothiazoles as potent MEK1 inhibitorsVARAPRASAD, Chamakura V. N. S; BARAWKAR, Dinesh; LANG, Stanley et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 15, pp 3975-3980, issn 0960-894X, 6 p.Article

Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis. CommentaryQUESNEL, Bruno; TAI, Yu-Tzu; PODAR, Klaus et al.Blood. 2007, Vol 110, Num 5, issn 0006-4971, 1402-1403, 1656-1663 [10 p.]Article

Constitutive activation of the Raf-MAPK pathway causes negative feedback inhibition of Ras-PI3K-AKT and cellular arrest through the EphA₂ receptorMENGES, C. W; MCCANCE, D. J.Oncogene (Basingstoke). 2008, Vol 27, Num 20, pp 2934-2940, issn 0950-9232, 7 p.Article

Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndromeSCHULZ, A. L; ALBRECHT, B; KÖNIG, R et al.Clinical genetics. 2008, Vol 73, Num 1, pp 62-70, issn 0009-9163, 9 p.Article

Phosphatidylinositol 3-kinase and Mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: A role for hypoxia-inducible factor-1?BURROUGHS, Kevin D; OH, Jennifer; BARRETT, J. Carl et al.Molecular cancer research. 2003, Vol 1, Num 4, pp 312-322, issn 1541-7786, 11 p.Article

Cot protooncoprotein activates the dual specificity kinases MEK-1 and SEK-1 and induces differentiation of PC12 cellsHAGEMANN, D; TROPPMAIR, J; RAPP, U. R et al.Oncogene (Basingstoke). 1999, Vol 18, Num 7, pp 1391-1400, issn 0950-9232Article

C-Jun N-TERMINAL KINASE BINDING DOMAIN-DEPENDENT PHOSPHORYLATION OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 AND MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 AND BALANCING CROSS-TALK BETWEEN c-Jun N-TERMINAL KINASE AND EXTRACELLULAR SIGNAL-REGULATED KINASE PATHWAYS IN CORTICAL NEURONSREPICI, M; MARE, L; COLOMBO, A et al.Neuroscience. 2009, Vol 159, Num 1, pp 94-103, issn 0306-4522, 10 p.Article

ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR functionWU, D; CHEN, B; TANG, D et al.Oncogene (Basingstoke). 2006, Vol 25, Num 8, pp 1153-1164, issn 0950-9232, 12 p.Article

MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and SrcZIMMERMANN, S; ROMMEL, C; ZIOGAS, A et al.Oncogene (Basingstoke). 1997, Vol 15, Num 13, pp 1503-1511, issn 0950-9232Article

Pharmacokinetic characterization of a natural product―inspired novel MEK1 inhibitor E6201 in preclinical speciesKUMAR, Vipul; SCHUCK, Edgar L; NANCY WONG, Y et al.Cancer chemotherapy and pharmacology. 2012, Vol 69, Num 1, pp 229-237, issn 0344-5704, 9 p.Article

Involvement of P2X₇ purinergic receptor and MEK1/2 in interleukin-8 up-regulation by LL-37 in human gingival fibroblastsMONTREEKACHON, P; CHOTJUMLONG, P; BOLSCHER, J. G. M et al.Journal of periodontal research. 2011, Vol 46, Num 3, pp 327-337, issn 0022-3484, 11 p.Article

Spectrum of MEK1 and MEK2 gene mutations in cardio-facio-cutaneous syndrome and genotype -phenotype correlationsDENTICI, Maria Lisa; SARKOZY, Anna; ZAMPINO, Giuseppe et al.European journal of human genetics. 2009, Vol 17, Num 6, pp 733-740, issn 1018-4813, 8 p.Article

Inhibition of CCL11, CCl24, and CCl26-induced degranulation in HL-60 eosinophilic cells by specific inhibitors of MEK1/MEK2, p38 MAP kinase, and PI 3-kinaseBADEWA, A. P; HEIMAN, A. S.Immunopharmacology and immunotoxicology. 2003, Vol 25, Num 2, pp 145-157, issn 0892-3973, 13 p.Article