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Results 1 to 25 of 65

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High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)NIEMI, Mikko; SCHAEFFELER, Elke; EICHELBAUM, Michel et al.Pharmacogenetics (London). 2004, Vol 14, Num 7, pp 429-440, issn 0960-314X, 12 p.Article

Factors Affecting the In Vivo Lactone Stability and Systemic Clearance of the Lipophilic Camptothecin Analogue AR-67ADANE, Eyob D; ZHIWEI LIU; XIANG, Tian-Xiang et al.Pharmaceutical research. 2010, Vol 27, Num 7, pp 1416-1425, issn 0724-8741, 10 p.Article

Molecular cloning and functional characterization of a rainbow trout liver OatpSTEINER, Konstanze; HAGENBUCH, Bruno; DIETRICH, Daniel R et al.Toxicology and applied pharmacology. 2014, Vol 280, Num 3, pp 534-542, issn 0041-008X, 9 p.Article

Fasting induces basolateral uptake transporters of the SLC family in the liver via HNF4α and PGC1αDIETRICH, Christoph G; MARTIN, Ina V; PORN, Anne C et al.American journal of physiology. Gastrointestinal and liver physiology. 2007, Vol 56, Num 3, issn 0193-1857, G585-G590Article

Mechanisms by which 2', 3'-dideoxyinosine (ddI) crosses the guinea-pig CNS barriers; relevance to HIV therapyGIBBS, J. E; JAYABALAN, P; THOMAS, S. A et al.Journal of neurochemistry. 2003, Vol 84, Num 4, pp 725-734, issn 0022-3042, 10 p.Article

Concentration-Dependent Effect of Naringin on Intestinal Absorption of β1-Adrenoceptor Antagonist Talinolol Mediated by P-Glycoprotein and Organic Anion Transporting Polypeptide (Oatp)SHIRASAKA, Yoshiyuki; YAN LI; SHIBUE, Yuta et al.Pharmaceutical research. 2009, Vol 26, Num 3, pp 560-567, issn 0724-8741, 8 p.Article

Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liverHUNG, Daniel Y; SIEBERT, Gerhard A; PING CHANG et al.British journal of pharmacology. 2005, Vol 145, Num 1, pp 57-65, issn 0007-1188, 9 p.Article

Involvement of Organic Anion Transporting Polypeptide la5 (OatplaS) in the Intestinal Absorption of Endothelin Receptor Antagonist in RatsTANI, Takeshi; GRAM, Luise K; ARAKAWA, Hiroshi et al.Pharmaceutical research. 2008, Vol 25, Num 5, pp 1085-1091, issn 0724-8741, 7 p.Article

Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytesJØRGENSEN, Lene; VAN BEEK, Johan; LUND, Søren et al.European journal of pharmaceutical sciences. 2007, Vol 30, Num 2, pp 181-189, issn 0928-0987, 9 p.Article

Intestinal Absorption of HMG-CoA Reductase Inhibitor Pravastatin Mediated by Organic Anion Transporting PolypeptideSHIRASAKA, Yoshiyuki; SUZUKI, Kensuke; NAKANISHI, Takeo et al.Pharmaceutical research. 2010, Vol 27, Num 10, pp 2141-2149, issn 0724-8741, 9 p.Article

Toxicological implications of hepatobiliary transportersKATO, Yukio; SUZUKI, Hiroshi; SUGIYAMA, Yuichi et al.Toxicology (Amsterdam). 2002, Vol 181-182, pp 287-290, issn 0300-483X, 4 p.Conference Paper

Molecular mechanisms of reduced glutathione transport : role of the MRP/CFTR/ABCC and OATP/SLC21A families of membrane proteinsBALLATORI, Nazzareno; HAMMOND, Christine L; CUNNINGHAM, Jennifer B et al.Toxicology and applied pharmacology. 2005, Vol 204, Num 3, pp 238-255, issn 0041-008X, 18 p.Article

Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspensionBADOLO, Lassina; MUNK RASMUSSEN, Louise; RÜSZ HANSEN, Helle et al.European journal of pharmaceutical sciences. 2010, Vol 40, Num 4, pp 282-288, issn 0928-0987, 7 p.Article

Characterization of hepatobiliary transport systems of a novel α4β1/α4β7 dual antagonist, TR-14035TSUDA-TSUKIMOTO, Minoru; MAEDA, Tomoji; IWANAGA, Takashi et al.Pharmaceutical research. 2006, Vol 23, Num 11, pp 2646-2656, issn 0724-8741, 11 p.Article

In Vitro and In Silico Strategies to Identify OATP I B I Inhibitors and Predict Clinical Drug―Drug InteractionsKARLGREN, Maria; AHLIN, Gustav; BERGSTRÖM, Christel A. S et al.Pharmaceutical research. 2012, Vol 29, Num 2, pp 411-426, issn 0724-8741, 16 p.Article

Efflux transport systems for organic anions and cations at the blood-CSF barrierKUSUHARA, Hiroyuki; SUGIYAMA, Yuichi.Advanced drug delivery reviews. 2004, Vol 56, Num 12, pp 1741-1763, issn 0169-409X, 23 p.Article

Role of OATP-1B1 and/or OATP-1B3 in hepatic disposition of tyrosine kinase inhibitorsKHURANA, Varun; MINOCHA, Mukul; PAL, Dhananjay et al.Drug metabolism and drug interactions. 2014, Vol 29, Num 3, pp 179-190, issn 0792-5077, 12 p.Article

Oatp-associated uptake and toxicity of microcystins in primary murine whole brain cellsFEURSTEIN, D; HOIST, K; FISCHER, A et al.Toxicology and applied pharmacology. 2009, Vol 234, Num 2, pp 247-255, issn 0041-008X, 9 p.Article

Steroid hormones specifically modify the activity of organic anion transporting polypeptidesKOENEN, Anna; KÖCK, Kathleen; KEISER, Markus et al.European journal of pharmaceutical sciences. 2012, Vol 47, Num 4, pp 774-780, issn 0928-0987, 7 p.Article

The role of organic anion transporting polypeptides (OATPs/SLCOs) in the toxicity of different microcystin congeners in vitro: A comparison of primary human hepatocytes and OATP-transfected HEK293 cellsFISCHER, A; HOEGER, S. J; STEMMER, K et al.Toxicology and applied pharmacology. 2010, Vol 245, Num 1, pp 9-20, issn 0041-008X, 12 p.Article

Transfer of repaglinide in the dually perfused human placenta and the role of organic anion transporting polypeptides (OATPs)TERTTI, Kristiina; PETSALO, Aleksanteri; NIEMI, Mikko et al.European journal of pharmaceutical sciences. 2011, Vol 44, Num 3, pp 181-186, issn 0928-0987, 6 p.Article

Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytesDE BRUYN, Tom; YE, Zhi-Wei; PEETERS, Annelies et al.European journal of pharmaceutical sciences. 2011, Vol 43, Num 4, pp 297-307, issn 0928-0987, 11 p.Article

Oral drug delivery utilizing intestinal OATP transportersTAMAI, Ikumi.Advanced drug delivery reviews. 2012, Vol 64, Num 6, pp 508-514, issn 0169-409X, 7 p.Article

The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose rangeKALLIOKOSKI, Annikka; NEUVONEN, Mikko; NEUVONEN, Pertti J et al.British journal of clinical pharmacology. 2008, Vol 66, Num 6, pp 818-825, issn 0306-5251, 8 p.Article

A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1OSWALD, Stefan; SCHEUCH, Eberhard; CASCORBI, Ingolf et al.Journal of chromatography. B. 2006, Vol 830, Num 1, pp 143-150, issn 1570-0232, 8 p.Article

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