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Results 1 to 25 of 357

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Clinical Proof-of-Concept StudyWith MSDC-0160, a Prototype mTOT-Modulating Insulin SensitizerCOLCA, J. R; VANDERLUGT, J. T; ADAMS, W. J et al.Clinical pharmacology and therapeutics. 2013, Vol 93, Num 4, pp 352-359, issn 0009-9236, 8 p.Article

A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesisMAWJI, Imtiaz A; SIMPSON, Craig D; GRONDA, Marcela et al.Cancer research (Baltimore). 2007, Vol 67, Num 17, pp 8307-8315, issn 0008-5472, 9 p.Article

Prediction of Skin Sensitizers using Alternative Methods to Animal ExperimentationJOHANSSON, Henrik; LINDSTEDT, Malin.Basic & clinical pharmacology & toxicology (Print). 2014, Vol 115, Num 1, pp 110-117, issn 1742-7835, 8 p.Conference Paper

Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparumKELLY, Jane X; SMILKSTEIN, Martin J; COOPER, Roland A et al.Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 11, pp 4133-4140, issn 0066-4804, 8 p.Article

Chemical sensitizers and protectorsCOLEMAN, C. N.International journal of radiation oncology, biology, physics. 1998, Vol 42, Num 4, pp 781-783, issn 0360-3016Conference Paper

Dinitroazetidines Are a Novel Class of Anticancer Agents and Hypoxia-Activated Radiation Sensitizers Developed from Highly Energetic MaterialsSHOUCHENG NING; BEDNARSKI, Mark; ORONSKY, Bryan et al.Cancer research (Chicago, Ill.). 2012, Vol 72, Num 10, pp 2600-2608, issn 0008-5472, 9 p.Article

Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical libraryLALLY, Brian E; GEIGER, Geoffrey A; KOUMENIS, Constantinos et al.Cancer research (Baltimore). 2007, Vol 67, Num 18, pp 8791-8799, issn 0008-5472, 9 p.Article

Discrimination of haptens from prohaptens using the metabolically deficient Cprlow/low mouseCHIPINDA, Itai; BLACHERE, Francoise M; ANDERSON, Stacey E et al.Toxicology and applied pharmacology. 2011, Vol 252, Num 3, pp 268-272, issn 0041-008X, 5 p.Article

A quantitative approach to assess the potency of skin sensitizers in the elicitation phaseEZENDAM, Janine; VERMEULEN, Jolanda P; DE KLERK, Arja et al.Toxicology (Amsterdam). 2012, Vol 299, Num 1, pp 20-24, issn 0300-483X, 5 p.Article

Preparation and characterization of phospholipid-conjugated indocyanine green as a near-infrared probeSUGANAMI, Akiko; TOYOTA, Taro; HAYASHI, Hideki et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 24, pp 7481-7485, issn 0960-894X, 5 p.Article

Frontiers in cancer research : Antiangiogenic therapy: A universal chemosensitization strategy for cancer?KERBEL, Robert S.Science (Washington, D.C.). 2006, Vol 312, Num 5777, pp 1171-1175, issn 0036-8075, 5 p.Article

Antidiabetic and hypolipidemic potential of DRF 2519: a dual activator of PPAR-α and PPAR-γCHAKRABARTI, Ranjan; MISRA, Parimal; VIKRAMADITHYAN, Reeba K et al.European journal of pharmacology. 2004, Vol 491, Num 2-3, pp 195-206, issn 0014-2999, 12 p.Article

HEAT SHOCK PROTEIN 27-TARGETED HEPTAPEPTIDE OF THE PKCΔ CATALYTIC V5 REGION SENSITIZES TUMORS WITH RADIO- AND CHEMORESISTANCELEE, Hae-June; KIM, Eun-Ho; WOO DUCK SEO et al.International journal of radiation oncology, biology, physics. 2011, Vol 80, Num 1, pp 221-230, issn 0360-3016, 10 p.Article

Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitorsSIRISHA, Kalam; MADDELA CHANDRA SHEKHAR; UMASANKAR, Kulandaivelu et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 10, pp 3249-3254, issn 0968-0896, 6 p.Article

Overcoming human P-glycoprotein-dependent multidrug resistance with novel dihydro-β-agarofuran sesquiterpenesPERESTELO, Nayra R; SANCHEZ-CANETE, Maria P; GAMARRO, Francisco et al.European journal of medicinal chemistry. 2011, Vol 46, Num 10, pp 4915-4923, issn 0223-5234, 9 p.Article

Simultaneous Quantification of Oroxylin A and Its Metabolite Oroxylin A-7-O-Glucuronide: Application to a Pharmacokinetic Study in RatWENYUAN LIU; XIAOZHEN XU; FENG FENG et al.Chromatographia (Wiesbaden). 2011, Vol 74, Num 1-2, pp 75-81, issn 0009-5893, 7 p.Article

First biological evaluation of developed 3-benzyloxyfluorenes as novel class of MDR modulatorsKRUG, Martin; VOIGT, Burkhardt; BAUMERT, Christiane et al.European journal of medicinal chemistry. 2010, Vol 45, Num 6, pp 2683-2688, issn 0223-5234, 6 p.Article

Novel steroid carbamates reverse multidrug-resistance in cancer therapy and show linkage among efficacy, loci of drug action and P-glycoprotein's cellular localizationARGOV, Mirit; BOD, Tal; BATRA, Satish et al.European journal of pharmaceutical sciences. 2010, Vol 41, Num 1, pp 53-59, issn 0928-0987, 7 p.Article

Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancerLAM, Elaine T; AU, Jessie L.- S; JENSEN, Rhonda R et al.Cancer chemotherapy and pharmacology. 2010, Vol 66, Num 6, pp 1019-1029, issn 0344-5704, 11 p.Article

Immunomodulatory roles of topical dinitrochlorobenzene treatment in Herpes simplex virus infectionYAMAJI, Masahiro; SHUDO, Jutaro.International immunopharmacology (Print). 2009, Vol 9, Num 7-8, pp 984-989, issn 1567-5769, 6 p.Article

Search for MDR modulators : Design, syntheses and evaluations of N-substituted acridones for interactions with p-glycoprotein and MgSINGH, Palwinder; KAUR, Jatinder; KAUR, Prabhjit et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 6, pp 2423-2427, issn 0968-0896, 5 p.Article

Synthesis and antimultidrug resistance evaluation of icariin and its derivativesLIU, Dong-Fang; LI, Yan-Ping; OU, Tian-Miao et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 15, pp 4237-4240, issn 0960-894X, 4 p.Article

Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulatorsKLINKHAMMER, Werner; MÜLLER, Henrik; GLOBISCH, Christoph et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 6, pp 2524-2535, issn 0968-0896, 12 p.Article

A novel selective peroxisome proliferator-activator receptor-γ modulator : SPPARγM5 improves insulin sensitivity with diminished adverse cardiovascular effectsCHANG, Ching H; MCNAMARA, Lesley A; MCCANN, Margaret E et al.European journal of pharmacology. 2008, Vol 584, Num 1, pp 192-201, issn 0014-2999, 10 p.Article

Acridones circumvent P-glycoprotein-associated multidrug resistance (MDR) in cancer cellsGOPINATH, Vadiraj S; THIMMAIAH, Padma; THIMMAIAH, Kuntebommanahalli N et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 1, pp 474-487, issn 0968-0896, 14 p.Article

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