Discovery of loperamide as an antagonist of angiopoietin1 and angiopoietin2 by virtual screeningXING WEN GONG; JUN HUA MAI; YU HONG XU et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 7, pp 2388-2392, issn 0960-894X, 5 p.Article

3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)HSU, John T.-A; YEH, Teng-Kuang; CHANG, Yun-I et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 14, pp 4654-4659, issn 0960-894X, 6 p.Article

An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kitXIANMING DENG; WENJUN ZHOU; WEISBERG, Ellen et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 14, pp 4579-4584, issn 0960-894X, 6 p.Article

Modification of a promiscuous inhibitor shifts the inhibition from γ-secretase to FLT-3OKALA AMOMBO, Ghislaine Marlyse; KRAMER, Thomas; LO MONTE, Fabio et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 24, pp 7634-7640, issn 0960-894X, 7 p.Article

Discovery of 6-substituted 4-anilinoquinazolines with dioxygenated rings as novel EGFR tyrosine kinase inhibitorsLI, Dong-Dong; FEI FANG; LI, Jing-Ran et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 18, pp 5870-5875, issn 0960-894X, 6 p.Article

Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitorsDENGYOU ZHANG; JIN GAI; ZHONGJIE LIANG et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 17, pp 5169-5180, issn 0968-0896, 12 p.Article

Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitorsBODE, Christiane M; BOEZIO, Alessandro A; REX, Karen et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4089-4093, issn 0960-894X, 5 p.Article

Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agentsGANGJEE, Aleem; YING ZHAO; INNAT, Michael A et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 14, pp 4217-4225, issn 0968-0896, 9 p.Article

Pharmacophore modeling and virtual screening to identify potential RET kinase inhibitorsSHIH, Kuei-Chung; SHIAU, Chung-Wai; CHEW, Ting-Shou et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 15, pp 4490-4497, issn 0960-894X, 8 p.Article

Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: Improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacyKAWAKITA, Youichi; MIWA, Kazuhiro; TANAKA, Toshimasa et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 20, pp 6171-6180, issn 0968-0896, 10 p.Article

Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activityCHEN, Kuen-Feng; PAO, Kuan-Chuan; SU, Jung-Chen et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 20, pp 6144-6153, issn 0968-0896, 10 p.Article

Discovery of novel EGFR tyrosine kinase inhibitors by structure-based virtual screeningSIYUAN LI; XIANQIANG SUN; HONGLI ZHAO et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4004-4009, issn 0960-894X, 6 p.Article

Impedimetric biosensor for cancer cell detectionSEVEN, Basak; BOUROUROU, Mariem; ELOUARZAKI, Kamal et al.Electrochemistry communications. 2013, Vol 37, pp 36-39, issn 1388-2481, 4 p.Article

A fluorescent reporter of ATP binding-competent receptor kinasesSICARD, Renaud; DHUGURU, Jyothi; WENJUN LIU et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 17, pp 5532-5535, issn 0960-894X, 4 p.Article

Synthesis and evaluation of 1-(substituted)-3-prop-2-ynylureas as antiangiogenic agentsSANPHANYA, Kingkan; WATTANAPITAYAKUL, Suvara K; PRANGSAENGTONG, Orawin et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 8, pp 3001-3005, issn 0960-894X, 5 p.Article

Rapid biochemical synthesis of ¹¹C-labeled single chain variable fragment antibody for immuno-PET by cell-free protein synthesisMATSUDA, Takayoshi; FURUMOTO, Shozo; HIGUCHI, Kae et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 22, pp 6579-6582, issn 0968-0896, 4 p.Article

Yersinia pestis and Approaches to Targeting its Outer Protein H Protein-Tyrosine Phosphatase (YopH)BAHTA, M; BURKE, T. R.Current medicinal chemistry. 2012, Vol 19, Num 33, pp 5726-5734, issn 0929-8673, 9 p.Article

Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasisPETCH, Donna; ANDERSON, Rosaleen J; CUNNINGHAM, Anne et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 19, pp 5901-5914, issn 0968-0896, 14 p.Article

Synthesis and structure―activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitorsLEE, Jongkook; HAN, Sun-Young; CHONG OCK LEE et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4044-4048, issn 0960-894X, 5 p.Article

A first synthesis of ¹⁸F-radiolabeled lapatinib: a potential tracer for positron emission tomographic imaging of ErbB1/ErbB2 tyrosine kinase activityBASULI, Falguni; HAITAO WU; CHANGHUI LI et al.Journal of labelled compounds & radiopharmaceuticals. 2011, Vol 54, Num 9-10, pp 633-636, issn 0362-4803, 4 p.Article

Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-aminesJACOB KASPERSEN, Svein; SØRUM, Christopher; WILLASSEN, Veronica et al.European journal of medicinal chemistry. 2011, Vol 46, Num 12, pp 6002-6014, issn 0223-5234, 13 p.Article

Design, synthesis and biological evaluation of N-phenylsulfonylnicotinamide derivatives as novel antitumor inhibitorsHUI ZHANG; XIANG LU; ZHANG, Li-Rong et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 4, pp 1411-1416, issn 0968-0896, 6 p.Article

Design, synthesis and biological evaluation of pyrazolyl-thiazolinone derivatives as potential EGFR and HER-2 kinase inhibitorsQIU, Ke-Ming; WANG, Hai-Hong; WANG, Li-Ming et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 6, pp 2010-2018, issn 0968-0896, 9 p.Article

Synthesis of an aryloxy oxo pyrimidinone library that displays ALK-selective inhibitionSLAVISH, P. Jake; PRICE, Jeanine E; QIN JIANG et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 15, pp 4592-4596, issn 0960-894X, 5 p.Article

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90HUANG, Kenneth H; BARTA, Thomas E; HUGHES, Philip F et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 7, pp 2550-2554, issn 0960-894X, 5 p.Article