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Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activityYANG, Xiao-Zhi; YANG, Wen-Hui; XU, Yun-Gen et al.European journal of medicinal chemistry. 2012, Vol 57, pp 21-28, issn 0223-5234, 8 p.Article

Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatranSTANGIER, Joachim; FEURING, Martin.Blood coagulation & fibrinolysis. 2012, Vol 23, Num 2, pp 138-143, issn 0957-5235, 6 p.Article

Emerging anticoagulant drugsBATES, Shannon M; WEITZ, Jeffrey I.Arteriosclerosis, thrombosis, and vascular biology. 2003, Vol 23, Num 9, pp 1491-1500, issn 1079-5642, 10 p.Article

Current developments in antithrombotic therapy: The role of antithrombin agentsBREDDIN, H. K.Pathophysiology of haemostasis and thrombosis (Print). 2002, Vol 32, pp 1-8, issn 1424-8832, 8 p., SUP3Conference Paper

Ecarin chromogenic assay: A new method for quantitative determination of direct thrombin inhibitors like hirudinLANGE, U; NOWAK, G; BUCHA, E et al.Pathophysiology of haemostasis and thrombosis (Print). 2003, Vol 33, Num 4, pp 184-191, issn 1424-8832, 8 p.Article

A thrombin inhibitor from the gut of Boophilus microplus ticksGRAVINA RICCI, Clarisse; MICHEL PINTO, Antonio Frederico; BERGER, Markus et al.Experimental & applied acarology. 2007, Vol 42, Num 4, pp 291-300, issn 0168-8162, 10 p.Article

Orally active thrombin inhibitors. Part 1: Optimization of the P1-moietyMACK, Helmut; BAUCKE, Dorit; HORNBERGER, Wilfried et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 10, pp 2641-2647, issn 0960-894X, 7 p.Article

An overview of the direct thrombin inhibitor argatrobanWALENGA, Jeanine M.Pathophysiology of haemostasis and thrombosis (Print). 2002, Vol 32, pp 9-14, issn 1424-8832, 6 p., SUP3Conference Paper

New oral anticoagulant agents ― general features and outcomes in subsets of patients : GTH - State of the ArtSCHULMAN, Sam.Thrombosis and haemostasis. 2014, Vol 111, Num 4, pp 575-582, issn 0340-6245, 8 p.Article

Fluorinated dual antithrombotic compounds based on 1,4-benzoxazine scaffoldILIC, Milos; KIKELJ, Danijel; ILAS, Janez et al.European journal of medicinal chemistry. 2012, Vol 50, pp 255-263, issn 0223-5234, 9 p.Article

Conformationally restricted analogs of the direct thrombin inhibitor FM 19GIRNYS, Elizabeth A; PORTER, Vanessa R; MOSBERG, Henry I et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 24, pp 7425-7434, issn 0968-0896, 10 p.Article

Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activitiesILIC, Miloš; KONTOGIORGIS, Christos; HADJIPAVLOU-LITINA, Dimitra et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 16, pp 4705-4709, issn 0960-894X, 5 p.Article

Orally active thrombin inhibitors. Part 2: Optimization of the P2-moietyLANGE, Udo E. W; BAUCKE, Dorit; HORNBERGER, Wilfried et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 10, pp 2648-2653, issn 0960-894X, 6 p.Article

Antithrombin-independent thrombin inhibitors, but not direct factor Xa inhibitors, enhance thrombin generation in plasma through inhibition of thrombin-thrombomodulin-protein C systemFURUGOHRI, Taketoshi; SUGIYAMA, Nobutoshi; MORISHIMA, Yoshiyuki et al.Thrombosis and haemostasis. 2011, Vol 106, Num 6, pp 1076-1083, issn 0340-6245, 8 p.Article

Identification and characterization of a new member of snake venom thrombin inhibitors from Bothrops insularis using a proteomic approachOLIVEIRA-CARVALHO, Ana Lucia; RAMOS GUIMARAES, Patricia; ALVAREZ ABREU, Paula et al.Toxicon (Oxford). 2008, Vol 51, Num 4, pp 659-671, issn 0041-0101, 13 p.Article

In Vitro Effects of Argatroban, Lepirudin, Bivalirudin, and Danaparoid on Fibrin Gel PermeabilitySHU HE; WALLEN, Hakan; JOHNSSON, Hans et al.Seminars in thrombosis and hemostasis. 2008, Vol 34, pp 91-96, issn 0094-6176, 6 p., SUP1Article

Histamine release, an undesired effect of thrombin inhibitors with basic character, is mediated through direct activation of Gi proteinsSTEMPELJ, Mateja; ZORKO, Matjaz; PETEMEL, Luka et al.European journal of pharmacology. 2006, Vol 538, Num 1-3, pp 182-187, issn 0014-2999, 6 p.Article

Successful use of recombinant factor VIIa for management of severe menorrhagia in an adolescent with an acquired inhibitor of human thrombinGIOVANNINI, L; APPERT, A; MONPOUX, F et al.Acta paediatrica (Oslo). 2004, Vol 93, Num 6, pp 841-843, issn 0803-5253, 3 p.Article

Thrombin inhibitor, argatroban, prevents tumor cell migration and bone metastasisASANUMA, Kunihiro; WAKABAYASHI, Hiroki; HAYASHI, Tatsuya et al.Oncology. 2004, Vol 67, Num 2, pp 166-173, issn 0030-2414, 8 p.Article

The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysisSHU HE; BLOMBÄCK, Margareta; BARK, Niklas et al.Thrombosis and haemostasis. 2010, Vol 103, Num 5, pp 1076-1084, issn 0340-6245, 9 p.Article

Drug-Induced Liver Injury in Humans: The Case of XimelagatranKEISU, M; ANDERSSON, T. B.Handbook of experimental pharmacology. 2010, Vol 196, pp 407-418, issn 0171-2004, 12 p.Article

Preparation of L-proline based aeruginosin 298-A analogs: Optimization of the P1-moietyGUIJUN WANG; GOYAL, Navneet; HOPKINSON, Branden et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 14, pp 3798-3803, issn 0960-894X, 6 p.Article

Brasiliensin : a novel intestinal thrombin inhibitor from Triatoma brasiliensis (Hemiptera: Reduviidae) with an important role in blood intakeARAUJO, R. N; CAMPOS, I. T. N; TANAKA, A. S et al.International journal for parasitology. 2007, Vol 37, Num 12, pp 1351-1358, issn 0020-7519, 8 p.Article

Design and characterization of dipetacompinRI0H, a dipetalogastin II-derived, classical competitive thrombin inhibitorBITTER, Thomas; LOPEZ, Mercedes; NOWAK, Goetz et al.Thrombosis and haemostasis. 2007, Vol 97, Num 1, pp 139-145, issn 0340-6245, 7 p.Article

Determination of ximelagatran, melagatran and two intermediary metabolites in plasma by mixed-mode solid phase extraction and LC-MS/MSDUNER, Kristina; BÄCKSTRÖM, Jonas; MAGNELL, Niklas et al.Journal of chromatography. B. 2007, Vol 852, Num 1-2, pp 317-324, issn 1570-0232, 8 p.Article

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