Specific high-performance liquid chromatographic assay with ultraviolet detection for the determination of 1(2-chloroethyl)-3-sarcosinamide-1-nitrosourea in plasmaSUPKO, J. G; PHILLIPS, L. R; MALSPEIS, L et al.Journal of chromatography. B, Biomedical applications. 1996, Vol 677, Num 2, pp 351-362Article

DNA crosslinking, sister chromatid exchange and cytotoxicity of N-2-chloroethylnitrosoureas tethered to minor groove binding peptidesFA-XIAN CHEN; YI ZHANG; CHURCH, K. M et al.Carcinogenesis (New York. Print). 1993, Vol 14, Num 5, pp 935-940, issn 0143-3334Article

Evidence that covalent complex formation between BCNU-treated oligonucleotides and E. coli alkyltransferases requires the O⁶-alkylguanine functionGONZAGA, P. E; HARRIS, L; MARGISON, G. P et al.Nucleic acids research. 1990, Vol 18, Num 13, pp 3961-3966, issn 0305-1048, 6 p.Article

N-(2-chloroethyl)-N-nitrosoureas covalently bound to nonionic and monocationic lexitropsin dipeptides. Synthesis, DNA affinity binding characteristics, and reactions with ³²P-end-labeled DNACHURCH, K. M; WURDEMAN, R. L; YI ZHANG et al.Biochemistry (Easton). 1990, Vol 29, Num 29, pp 6827-6838, issn 0006-2960, 12 p.Article

Metabolism of the chloroethylnitrosoureasLEMOINE, A; LUCAS, C; INGS, R. M. J et al.Xenobiotica (London. Print). 1991, Vol 21, Num 6, pp 775-791, issn 0049-8254, 17 p.Article

Depletion of O⁶-methylguanine-DNA methyltransferase and potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea antitumor activity by O⁶-benzylguanine in vitroJIAN-MIN CHEN; YANG-PEI ZHANG; MOSCHEL, R. C et al.Carcinogenesis (New York. Print). 1993, Vol 14, Num 5, pp 1057-1060, issn 0143-3334Article

N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenicINGA, A; CHEN, F.-X; FRONZA, G et al.Cancer research (Baltimore). 1999, Vol 59, Num 3, pp 689-695, issn 0008-5472Article

Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylaseMATIJASEVIC, Z; BOOSALIS, M; MACKAY, W et al.Proceedings of the National Academy of Sciences of the United States of America. 1993, Vol 90, Num 24, pp 11855-11859, issn 0027-8424Article

Identification of the cross-linke between human O⁶-methylguanine-DNA methyltransferase and choroethylnitrosourea-treated DNAGONZAGA, P. E; POTTER, P. M; TIAN-QI NIU et al.Cancer research (Baltimore). 1992, Vol 52, Num 21, pp 6052-6058, issn 0008-5472Article

Correlation of chloroethylnitrosourea resistance with ERCC-2 expression in human tumor cell lines as determined by quantitative competitive polymerase chain reactionCHEN, Z.-P; MALAPETSA, A; MARCANTONIO, D et al.Cancer research (Baltimore). 1996, Vol 56, Num 11, pp 2475-2478, issn 0008-5472Article

Hydroxyethylation of hemoglobin by 1-(2-chloroethyl)-1-nitrosoureasBAILEY, E; FARMER, P. B; YUK-SIM TANG et al.Chemical research in toxicology. 1991, Vol 4, Num 4, pp 462-466, issn 0893-228XArticle

Activation of human O⁶-methylguanine-DNA methyltransferase gene by glucocorticoid hormoneBISWAS, T; RAMANA, C. V; SRINIVASAN, G et al.Oncogene (Basingstoke). 1999, Vol 18, Num 2, pp 525-532, issn 0950-9232Article

Development of resistance to antitumor chloroethylnitrosoureas in vitro in brain tumor cellsMINEURA, K; ISHIYAMA, Y; KOWADA, M et al.Acta oncologica (Stockholm). 1992, Vol 31, Num 7, pp 755-759, issn 0284-186XArticle

Expression of human O⁶-methylguanine-DNA methyltransferase in a DNA excision repair-deficient chinese hamster ovary cell line and its response to certain alkylating agentsZINING WU; CHUNG-LEUNG CHAN; EASTMAN, A et al.Cancer research (Baltimore). 1992, Vol 52, Num 1, pp 32-35, issn 0008-5472Article

The relationship of a novel drug-resistant phenotype in C3H10T1/2 cells selected with alkylating agents to neoplastic transformation and ATP metabolismWROBLEWSKI-GIORGIO, D; VON HOFE, E.Cancer letters. 1997, Vol 113, Num 1-2, pp 195-203, issn 0304-3835Article

Influence of O⁶-methylguanine-DNA methyltransferase activity on chloroethylnitrosourea chemotherapy in brain tumorsMINEURA, K; IZUMI, I; WATANABE, K et al.International journal of cancer. 1993, Vol 55, Num 1, pp 76-81, issn 0020-7136Article

The chloroethylnitrosoureas : Sensitivity and resistance to cancer chemotherapy at the molecular levelLUDLUM, D. B.Cancer investigation. 1997, Vol 15, Num 6, pp 588-598, issn 0735-7907Article

Detection of N7-(2-hydroxyethyl)guanine adducts in DNA and 9L cells treated with 1-(2-chloroethyl)-1-nitrosoureaYE, Q; BODELL, W. J.Journal of chromatography. B, Biomedical sciences and applications. 1997, Vol 694, Num 1, pp 65-70, issn 1387-2273Article

The role of mRNA stability and transcription in 0⁶-methylguanine DNA methyltransferase (MGMT) expression in Mer⁺ human tumor cellsKROES, R. A; ERICKSON, L. C.Carcinogenesis (New York. Print). 1995, Vol 16, Num 9, pp 2255-2257, issn 0143-3334Article

Chemotherapy inhibits skeletal muscle ubiquitin-proteasome-dependent proteolysisTILIGNAC, Thomas; TEMPARIS, Sandrine; MADELMONT, Jean-Claude et al.Cancer research (Baltimore). 2002, Vol 62, Num 10, pp 2771-2777, issn 0008-5472Article

In the search for new anticancer drugs. XXIV: Synthesis and anticancer activity of amino acids and dipeptides containing the 2-chloroethyl- and [N'-(2-chloroethyl)-N'-nitroso]-aminocarbonyl groupsSOSNOVSKY, G; INDRA PRAKASH; NUTI UMA MAHESWARA RAO et al.Journal of pharmaceutical sciences. 1993, Vol 82, Num 1, pp 1-10, issn 0022-3549Article

Pharmacokinetics and cytotoxicity of B.3839, a molecular combination of 5-fluorouracil and N-(2-chloethyl)-N-nitrosourea, in a mouse modelLOADMAN, P. M; BIBBY, M. C; DOUBLE, J. A et al.Investigational new drugs. 1992, Vol 10, Num 3, pp 149-158, issn 0167-6997Article

SarCNU (2-chloroethyl-3-sarcosinamide-1-nitrosourea) : a novel analogue of chloroethylnitrosourea that is transported by the catecholamine uptake₂ carrier, which mediates increased cytotoxityPANASCI, L. C; MARCANTONIO, D; NOË, A. J et al.Cancer chemotherapy and pharmacology. 1996, Vol 37, Num 6, pp 505-508, issn 0344-5704Article

Wild-type p53 suppresses transcription of the human O₆-methylguanine-DNA methyltransferase geneHARRIS, L. C; REMACK, J. S; HOUGHTON, P. J et al.Cancer research (Baltimore). 1996, Vol 56, Num 9, pp 2029-2032, issn 0008-5472Article

Potentiation of BCNU anticancer activity by o⁶-benzylguanine : A study in vitro and in vivoYONGLING WAN; DEZHENG WU; HONGZHI GAO et al.Journal of environmental pathology, toxicology and oncology. 2000, Vol 19, Num 1-2, pp 69-75, issn 0731-8898Article