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Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surfaceCONRAN, Nicola; GAMBERO, Alessandra; FERREIRA, Heloisa H. A et al.Biochemical pharmacology. 2003, Vol 66, Num 1, pp 43-50, issn 0006-2952, 8 p.Article

High frequency of adhesion defects in B-lineage acute lymphoblastic leukemiaGEIJTENBEEK, T. B. H; VAN KOOYK, Y; VAN VLIET, S. J et al.Blood. 1999, Vol 94, Num 2, pp 754-764, issn 0006-4971Article

The gene for the α4 subunit of the VLA-4 integrin maps to chromosome 2Q31-32ZHUOHUA ZHANG; VEKEMANS, S; ALY, M. S et al.Blood. 1991, Vol 78, Num 9, pp 2396-2399, issn 0006-4971Article

Therapeutic implications of α4 integrinsELICES, MARIANO.Springer seminars in immunopathology. 1995, Vol 16, Num 4, issn 0344-4325, 124 p.Serial Issue

Essential roles of VLA-4 in the hematopoietic systemIMAI, Yoichi; SHIMAOKA, Motomu; KUROKAWA, Mineo et al.International journal of hematology. 2010, Vol 91, Num 4, pp 569-575, issn 0925-5710, 7 p.Article

Different adhesive characteristics and VLA-4 expression of CD34+ progenitors in G0/G1 versus S+G2/M phases of the cell cycleYAMAGUCHI, M; IKEBUCHI, K; HIRAYAMA, F et al.Blood. 1998, Vol 92, Num 3, pp 842-848, issn 0006-4971Article

Constraining the amide bond in N-Sulfonylated dipeptide VLA-4 antagonistsCHANG, Linda L; YANG, Ginger X; MCCAULEY, Ermengilda et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 5, pp 1688-1691, issn 0960-894X, 4 p.Article

Vicious cycle between myeloma cell binding to bone marrow stromal cells via VLA-4-VCAM-1 adhesion and macrophage inflammatory protein-1α and MIP-1β productionABE, Masahiro; HIURA, Kenji; OZAKI, Shuji et al.Journal of bone and mineral metabolism (English ed.). 2009, Vol 27, Num 1, pp 16-23, issn 0914-8779, 8 p.Article

Blocking α4-integrins : A small molecule approach to treatment of multiple sclerosisDAVENPORT, Richard J; MUNDAY, James R.Journal of the neurological sciences. 2008, Vol 274, Num 1-2, pp 27-30, issn 0022-510X, 4 p.Conference Paper

Pyridone derivatives as potent and selective VLA-4 integrin antagonistsWITHERINGTON, Jason; BORDAS, Vincent; GAIBA, Alessandra et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 8, pp 2256-2259, issn 0960-894X, 4 p.Article

Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma modelSEMKO, Christopher M; LINDA CHEN; LIAO, Anna et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 6, pp 1741-1743, issn 0960-894X, 3 p.Article

IL-4 Suppresses Very Late Antigen-4 Expression Which is Required for Therapeutic Th1 T-cell Trafficking Into TumorsSASAKI, Kotaro; PARDEE, Angela D; BASSE, Per H et al.Journal of immunotherapy (1997). 2009, Vol 32, Num 8, pp 793-802, issn 1524-9557, 10 p.Article

Selection of a 2-azabicyclo[2.2.2]octane-based α4β1 integrin antagonist as an inhaled anti-asthmatic agentLAWSON, Edward C; SANTULLI, Rosemary J; MARYANOFF, Bruce E et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 12, pp 4208-4216, issn 0968-0896, 9 p.Article

Evidence for cell adhesion-mediated drug resistance of multiple myeloma cells in vivoSCHMIDMAIER, R; MÖRSDORF, K; BAUMANN, P et al.The International journal of biological markers. 2006, Vol 21, Num 4, pp 218-222, issn 0393-6155, 5 p.Article

Increased expression of neutrophil and monocyte adhesion molecules LFA-1 and Mac-1 and their ligand ICAM-1 and VLA-4 throughout the acute phase of myocardial infarction possible implications for leukocyte aggregation and microvascular pluggingMEISEL, S. R; SHAPIRO, H; RADNAY, J et al.Journal of the American College of Cardiology. 1998, Vol 31, Num 1, pp 120-125, issn 0735-1097Article

Identification of trans-4-[1-[[7-fluoro-2-(1-methyl-3-indolyl)-6-benzoxazolyl]acetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid as a potent, orally active VLA-4 antagonistSETOGUCHI, Masaki; IIMURA, Shin; TAIRA, Tomoe et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 3, pp 1201-1212, issn 0968-0896, 12 p.Article

Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4RETTIG, M. P; ANSSTAS, G; DIPERSIO, J. F et al.Leukemia. 2012, Vol 26, Num 1, pp 34-53, issn 0887-6924, 20 p.Article

High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapseSHALAPOUR, Shabnam; HOF, Jana; KIRSCHNER-SCHWABE, Renate et al.Haematologica (Roma). 2011, Vol 96, Num 11, pp 1627-1635, issn 0390-6078, 9 p.Article

PLZF-mediated control on VLA-4 expression in normal and leukemic myeloid cellsQUARANTA, M. T; SPINELLO, I; TESTA, U et al.Oncogene (Basingstoke). 2006, Vol 25, Num 3, pp 399-408, issn 0950-9232, 10 p.Article

Aza-bicyclic amino acid carboxamides as α4β14β7 integrin receptor antagonistsDYATKIN, Alexey B; YONG GONG; DIAMOND, Craig et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 24, pp 6693-6702, issn 0968-0896, 10 p.Article

High-throughput pharmacokinetics screen of VLA-4 antagonists by LC/MS/MS coupled with automated solid-phase extraction sample preparationTONG, Xinchun S; JUNYING WANG; SONG ZHENG et al.Journal of pharmaceutical and biomedical analysis. 2004, Vol 35, Num 4, pp 867-877, issn 0731-7085, 11 p.Article

Macrophage brain infiltration in experimental autoimmune encephalomyelitis is not completely compromised by suppressed T-cell invasion: in vivo magnetic resonance imaging illustration in effective anti-VLA-4 antibody treatmentDELOIRE, Mathilde S. A; TOUIL, Tarik; BROCHET, Bruno et al.Multiple sclerosis. 2004, Vol 10, Num 5, pp 540-548, issn 1352-4585, 9 p.Article

Natalizumab treatment alters the expression of T-cell trafficking marker LFA-I α-chain (CDIIa) in MS patientsJILEK, Samantha; MATHIAS, Amandine; CANALES, Mathieu et al.Multiple sclerosis. 2014, Vol 20, Num 7, pp 837-842, issn 1352-4585, 6 p.Article

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after strokeLIESZ, Arthur; WEI ZHOU; SOMMER, Clemens et al.Brain. 2011, Vol 134, pp 704-720, issn 0006-8950, 17 p., 3Article

Establishment of an HS23 stromal cell-dependent myeloma cell line: fibronectin and IL-6 are criticalSAKAI, Akira; ODA, Miyo; ITAGAKI, Mitsuhiro et al.International journal of hematology. 2010, Vol 92, Num 4, pp 598-608, issn 0925-5710, 11 p.Article

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