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Anxiogenic properties of an inverse agonist selective for α3 subunit-containing GABAA receptorsATACK, John R; HUTSON, Peter H; DAWSON, Gerard R et al.British journal of pharmacology. 2005, Vol 144, Num 3, pp 357-366, issn 0007-1188, 10 p.Article

SB265610 is an allosteric, inverse agonist at the human CXCR2 receptorBRADLEY, M. E; BOND, M. E; MANINI, J et al.British journal of pharmacology. 2009, Vol 158, Num 1, pp 328-338, issn 0007-1188, 11 p.Article

4,5-Dihydropyridazin-3-one derivatives as histamine H3 receptor inverse agonistsHUDKINS, Robert L; AIMONE, Lisa D; ZULLI, Allison L et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 1, pp 194-198, issn 0960-894X, 5 p.Article

Inverse agonism or neutral antagonism at G-protein coupled receptors : A médicinal chemistry challenge worth pursuing?GREASLEY, Peter J; CLAPHAM, John C.European journal of pharmacology. 2006, Vol 553, Num 1-3, pp 1-9, issn 0014-2999, 9 p.Article

Role of GABAA α5-containing receptors in ethanol reward : The effects of targeted gene deletion, and a selective inverse agonistSTEPHENS, David N; PISTOVCAKOVA, Jana; WORTHING, Lynn et al.European journal of pharmacology. 2005, Vol 526, Num 1-3, pp 240-250, issn 0014-2999, 11 p.Conference Paper

Pharmacological characterization of the cannabinoid CB1 receptor PET ligand ortholog, [3H]MePPEPSUTER, Todd M; CHESTERFIELD, Amy K; CHUN BAO et al.European journal of pharmacology. 2010, Vol 649, Num 1-3, pp 44-50, issn 0014-2999, 7 p.Article

Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonistESBENSHADE, Timothy A; FOX, Gerard B; FAGHIH, Ramin et al.Biochemical pharmacology. 2004, Vol 68, Num 5, pp 933-945, issn 0006-2952, 13 p.Article

Benzodiazepine agonist and inverse agonist coupling in GABAA receptors antagonized by increased atmospheric pressureDAVIES, Daryl L; ALKANA, Ronald L.European journal of pharmacology. 2003, Vol 469, Num 1-3, pp 37-45, issn 0014-2999, 9 p.Article

A Small Molecule Inverse Agonist for the Human Thyroid-Stimulating Hormone ReceptorNEUMANN, Susanne; WENWEI HUANG; ELISEEVA, Elena et al.Endocrinology (Philadelphia). 2010, Vol 151, Num 7, pp 3454-3459, issn 0013-7227, 6 p.Article

Investigation of the mechanism of agonist and inverse agonist action at D2 dopamine receptorsROBERTS, David J; HONG LIN; STRANGE, Philip G et al.Biochemical pharmacology. 2004, Vol 67, Num 9, pp 1657-1665, issn 0006-2952, 9 p.Article

Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonistFUMAGALLI, Laura; PALLAVICINI, Marco; VALOTI, Ermanno et al.European journal of medicinal chemistry. 2012, Vol 58, pp 184-191, issn 0223-5234, 8 p.Article

Suppression of thyrotropin receptor constitutive activity by a monoclonal antibody with inverse agonist activityCHEN, Chun-Rong; MCLACHLAN, Sandra M; RAPOPORT, Basil et al.Endocrinology (Philadelphia). 2007, Vol 148, Num 5, pp 2375-2382, issn 0013-7227, 8 p.Article

ARB and Cardioprotection : NEW ASPECTS OF THE RENIN-ANGIOTENSIN ALDOSTERONE SYSTEM (RAAS) IN CARDIOVASCULAR DISEASEAKAZAWA, Hiroshi; YABUMOTO, Chizuru; YANO, Masamichi et al.Cardiovascular drugs and therapy. 2013, Vol 27, Num 2, pp 155-160, issn 0920-3206, 6 p.Article

Synthesis of constrained benzocinnolinone analogues of CEP-26401 (irdabisant) as potent, selective histamine H3 receptor inverse agonistsJOSEF, Kurt A; AIMONE, Lisa D; LYONS, Jacquelyn et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 12, pp 4198-4202, issn 0960-894X, 5 p.Article

Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligandsKOTTKE, Tim; SANDER, Kerstin; WEIZEL, Lilia et al.European journal of pharmacology. 2011, Vol 654, Num 3, pp 200-208, issn 0014-2999, 9 p.Article

In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligandsCASCIO, M. G; BISOGNO, T; BRIZZI, V et al.British journal of pharmacology. 2006, Vol 149, Num 4, pp 431-440, issn 0007-1188, 10 p.Article

Molecular basis of melanocortin-4 receptor for AGRP inverse agonismMIN CHEN; CELIK, Ahmet; GEORGESON, Keith E et al.Regulatory peptides. 2006, Vol 136, Num 1-3, pp 40-49, issn 0167-0115, 10 p.Article

Some implications of receptor theory for in vivo assessment of agonists, antagonists and inverse agonistsNEGUS, S. Steuens.Biochemical pharmacology. 2006, Vol 71, Num 12, pp 1663-1670, issn 0006-2952, 8 p.Article

The challenge of drug discovery of a GPCR target : Analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonistsHANCOCK, A. A.Biochemical pharmacology. 2006, Vol 71, Num 8, pp 1103-1113, issn 0006-2952, 11 p.Article

The effects of a novel histamine-3 receptor inverse agonist on essential tremor in comparison to stable levels of alcoholZOETHOUT, Rwm; IANNONE, R; VAN DYCK, K et al.Journal of psychopharmacology (Oxford). 2012, Vol 26, Num 2, pp 292-302, issn 0269-8811, 11 p.Article

An efficient synthesis of 3-OBn-6β,14-epoxy-bridged opiates from naltrexone and identification of a related dual MOR inverse agonist/KOR agonistMARTIN, David J; FITZMORRIS, Paul E; BO LI et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 22, pp 6801-6805, issn 0960-894X, 5 p.Article

Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activitySUNDAR, Babu G; BAILEY, Thomas R; LYONS, Jacquelyn et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 4, pp 1546-1549, issn 0960-894X, 4 p.Article

Involvement of cannabinoid CB2 receptor-mediated response and efficacy of cannabinoid CB2 receptor inverse agonist, JTE-907, in cutaneous inflammation in miceUEDA, Yoshifumi; MIYAGAWA, Naoki; MATSUI, Tomoko et al.European journal of pharmacology. 2005, Vol 520, Num 1-3, pp 164-171, issn 0014-2999, 8 p.Article

4-Phenoxypiperidine pyridazin-3-one histamine H3 receptor inverse agonists demonstrating potent and robust wake promoting activityHUDKINS, Robert L; ZULLI, Allison L; RADDATZ, Rita et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 4, pp 1504-1509, issn 0960-894X, 6 p.Article

Recent Advance in the Design of Small Molecular Modulators of Estrogen-Related ReceptorsXIAOYUN LU; LIJIE PENG; LV, Man et al.Current pharmaceutical design (Print). 2012, Vol 18, Num 23, pp 3421-3431, issn 1381-6128, 11 p.Article

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