The effects of a novel metabotropic glutamate receptor 5 antagonist (AZD2066) on transient lower oesophageal sphincter relaxations and reflux episodes in healthy volunteersROHOF, W. O; LEI, A; HIRSCH, D. P et al.Alimentary pharmacology & therapeutics. 2012, Vol 35, Num 10, pp 1231-1242, issn 0269-2813, 12 p.Article

Metabotropic Glutamate 5 Receptor (mGluR5) Antagonists Decrease Nicotine Seeking, But Do Not Affect the Reinforcement Enhancing Effects of NicotinePALMATIER, Matthew I; XIU LIU; DONNY, Eric C et al.Neuropsychopharmacology (New York, NY). 2008, Vol 33, Num 9, pp 2139-2147, issn 0893-133X, 9 p.Article

A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 ― Estimating occupancy in the absence of a reference regionKAGEDAL, Matts; CSELENYI, Zsolt; NYBERG, Svante et al.NeuroImage (Orlando, Fla.). 2013, Vol 82, pp 160-169, issn 1053-8119, 10 p.Article

Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulatorSPEAR, Nathan; GADIENT, Reto A; WILKINS, Deidre E et al.European journal of pharmacology. 2011, Vol 659, Num 2-3, pp 146-154, issn 0014-2999, 9 p.Article

Effects of a metabotropic, MGLU5, glutamate receptor antagonist on ethanol consumption by genetic drinking ratsMCMILLEN, Brian A; CRAWFORD, Monica S; KULERS, Cortney M et al.Alcohol and alcoholism (Oxford). 2005, Vol 40, Num 6, pp 494-497, issn 0735-0414, 4 p.Article

Proteomic analysis of native metabotropic glutamate receptor 5 protein complexes reveals novel molecular constituentsFARR, Carol D; GAFKEN, Philip R; NORBECK, Angela D et al.Journal of neurochemistry. 2004, Vol 91, Num 2, pp 438-450, issn 0022-3042, 13 p.Article

Cue-conditioned alcohol seeking in rats following abstinence: involvement of metabotropic glutamate 5 receptorsADAMS, C. L; SHORT, J. L; LAWRENCE, A. J et al.British journal of pharmacology. 2010, Vol 159, Num 3, pp 534-542, issn 0007-1188, 9 p.Article

The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotineTRONCI, Valeria; VRONSKAYA, Svetlana; MONTGOMERY, Nicholas et al.Psychopharmacologia. 2010, Vol 211, Num 1, pp 33-42, issn 0033-3158, 10 p.Article

Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptorsLEA, Paul M; MOVSESYAN, Vilen A; FADEN, Alan I et al.British journal of pharmacology. 2005, Vol 145, Num 4, pp 527-534, issn 0007-1188, 8 p.Article

Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonistPAŁUCHA, Agnieszka; BRANSKI, Piotr; SZEWCZYK, Bernadeta et al.Pharmacology, biochemistry and behavior. 2005, Vol 81, Num 4, pp 901-906, issn 0091-3057, 6 p.Article

Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux diseaseZERBIB, F; BRULEY DES VARANNES, S; ROMAN, S et al.Alimentary pharmacology & therapeutics. 2011, Vol 33, Num 8, pp 911-921, issn 0269-2813, 11 p.Article

Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests 'anxiolytic' effects are mediated by different mechanismsGEORGE, S. A; HUTSON, P. H; STEPHENS, D. N et al.Psychopharmacologia. 2009, Vol 204, Num 3, pp 499-509, issn 0033-3158, 11 p.Article

Assessing appetitive and consummatory phases of ethanol self-administration in C57BL/6J mice under operant conditions : regulation by mGlu5 receptor antagonismCOWEN, Michael S; KRSTEW, Elena; LAWRENCE, Andrew J et al.Psychopharmacologia. 2007, Vol 190, Num 1, pp 21-29, issn 0033-3158, 9 p.Article

The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J miceHODGE, Clyde W; MILES, Michael F; SHARKO, Amanda C et al.Psychopharmacologia. 2006, Vol 183, Num 4, pp 429-438, issn 0033-3158, 10 p.Article

Effects of metabotropic glutamate receptor 5 on latent inhibition in conditioned taste aversionBILLS, Carla; SCHACHTMAN, Todd R; SERFOZO, Peter et al.Behavioural brain research. 2005, Vol 157, Num 1, pp 71-78, issn 0166-4328, 8 p.Article

Behavioral consequences of the mGlu5 receptor antagonist MTEP in immature ratsTICHA, Katerina; MIKULECKA, Anna; MARES, Pavel et al.Pharmacology, biochemistry and behavior. 2011, Vol 99, Num 4, pp 619-625, issn 0091-3057, 7 p.Article

Blockade of mGLUR5 receptors differentially alters amphetamine-induced enhancement of locomotor activity and of brain stimulation rewardGORMLEY, Stéphanie; ROMPRE, Pierre-Paul.Journal of psychopharmacology (Oxford). 2011, Vol 25, Num 3, pp 393-401, issn 0269-8811, 9 p.Article

Determination of key amino acids implicated in the actions of allosteric modulation by 3,3'-difluorobenzaldazine on rat mGlu5 receptorsMÜHLEMANN, Andreas; WARD, Natalie A; KRATOCHWIL, Nicole et al.European journal of pharmacology. 2006, Vol 529, Num 1-3, pp 95-104, issn 0014-2999, 10 p.Article

mGlu₅ receptors are involved in the discriminative stimulus effects of self-administered ethanol in ratsBESHEER, Joyce; STEVENSON, Rebekah A; HODGE, Clyde W et al.European journal of pharmacology. 2006, Vol 551, Num 1-3, pp 71-75, issn 0014-2999, 5 p.Article

Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodentsPAGE, Michelle E; SZELIGA, Paul; GASPARINI, Fabrizio et al.Psychopharmacologia. 2005, Vol 179, Num 1, pp 240-246, issn 0033-3158, 7 p.Article

Significant increase in anxiety during aging in mGlu5 receptor knockout miceINTA, D; VOGT, M. A; LUONI, A et al.Behavioural brain research. 2013, Vol 241, pp 27-31, issn 0166-4328, 5 p.Article

N-Aryl pyrrolidinonyl oxadiazoles as potent mGluR5 positive allosteric modulatorsPACKIARAJAN, Mathivanan; MAZZA FERREIRA, Christine G; HONG, Sang-Phyo et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 17, pp 5658-5662, issn 0960-894X, 5 p.Article

The role of metabotropic glutamate receptor mGlu5 in control of micturition and bladder nociceptionYOUMIN HU; LI DONG; WEIFANG RONG et al.Neuroscience letters. 2009, Vol 450, Num 1, pp 12-17, issn 0304-3940, 6 p.Article

Positive Allosteric Modulation of mGluR5 Receptors Facilitates Extinction of a Cocaine Contextual MemoryGASS, Justin T; OLIVE, M. Foster.Biological psychiatry (1969). 2009, Vol 65, Num 8, pp 717-720, issn 0006-3223, 4 p.Article

Effects of MPEP on avoidance learning in ratsGENKOVA-PAPAZOV, M; PETKOVA, B; STANKOVA, I et al.Methods and findings in experimental and clinical pharmacology. 2007, Vol 29, Num 3, pp 205-209, issn 0379-0355, 5 p.Article