Minodronic acid, a third-generation bisphosphonate, antagonizes purinergic P2X_2/3 receptor function and exerts an analgesic effect in pain modelsKAKIMOTO, Shuichiro; NAGAKURA, Yukinori; TAMURA, Seiji et al.European journal of pharmacology. 2008, Vol 589, Num 1-3, pp 98-101, issn 0014-2999, 4 p.Article

Effect of combined teriparatide and monthly minodronic acid therapy on cancellous bone mass in ovariectomized rats: A bone histomorphometry studyIWAMOTO, Jun; SEKI, Azusa; SATO, Yoshihiro et al.Bone (New York, NY). 2014, Vol 64, pp 88-94, issn 8756-3282, 7 p.Article

Effect of minodronic acid hydrate on hip geometry in Japanese women with postmenopausal osteoporosisITO, Masako; SONE, Teruki; FUKUNAGA, Masao et al.Journal of bone and mineral metabolism (English ed.). 2010, Vol 28, Num 3, pp 334-341, issn 0914-8779, 8 p.Article

Effects of minodronic acid and alendronate on bone remodeling, microdamage accumulation, degree of mineralization and bone mechanical properties in ovariectomized cynomolgus monkeysYAMAGAMI, Yoshiki; MASHIBA, Tasuku; IWATA, Ken et al.Bone (New York, NY). 2013, Vol 54, Num 1, pp 1-7, issn 8756-3282, 7 p.Article

Intermittent minodronic acid treatment with sufficient bone resorption inhibition prevents reduction in bone mass and strength in ovariectomized rats with established osteopenia comparable with daily treatmentKIMOTO, Aishi; TANAKA, Makoto; NOZAKI, Kazutoshi et al.Bone (New York, NY). 2013, Vol 55, Num 1, pp 189-197, issn 8756-3282, 9 p.Article

Minodronic acid (ONO-5920/YM529) prevents decrease in bone mineral density and bone strength, and improves bone microarchitecture in ovariectomized cynomolgus monkeysMORI, Hiroshi; TANAKA, Makoto; KAYASUGA, Ryoji et al.Bone (New York, NY). 2008, Vol 43, Num 5, pp 840-848, issn 8756-3282, 9 p.Article

A new stressed test to predict the foreign matter formation of minodronic acid in solutionNAKAMURA, Katsutoshi; YOKOHAMA, Shigeharu; KATSUMA, Masataka et al.International journal of pharmaceutics. 2003, Vol 251, Num 1-2, pp 99-106, issn 0378-5173, 8 p.Article

Long-term minodronic acid (ONO-5920/YM529) treatment suppresses increased bone turnover, plus prevents reduction in bone mass and bone strength in ovariectomized rats with established osteopeniaTANAKA, Makoto; MORI, Hiroshi; KAYASUGA, Ryoji et al.Bone (New York, NY). 2008, Vol 43, Num 5, pp 894-900, issn 8756-3282, 7 p.Article

A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivoSATO, K; YUASA, T; NOGAWA, M et al.British journal of cancer. 2006, Vol 95, Num 10, pp 1354-1361, issn 0007-0920, 8 p.Article

Effects of minodronate on cortical bone response to mechanical loading in ratsNAGIRA, Keita; HAGINO, Hiroshi; KAMEYAMA, Yasuhiro et al.Bone (New York, NY). 2013, Vol 53, Num 1, pp 277-283, issn 8756-3282, 7 p.Article

A double-blinded head-to-head trial of minodronate and alendronate in women with postmenopausal osteoporosisHAGINO, Hiroshi; NISHIZAWA, Yoshiki; MINAMIDE, Toshiomi et al.Bone (New York, NY). 2009, Vol 44, Num 6, pp 1078-1084, issn 8756-3282, 7 p.Article

Three years of treatment with minodronate in patients with postmenopausal osteoporosisHAGINO, Hiroshi; SHIRAKI, Masataka; FUKUNAGA, Masao et al.Journal of bone and mineral metabolism (English ed.). 2012, Vol 30, Num 4, pp 439-446, issn 0914-8779, 8 p.Article

Stabilization of minodronic acid in aqueous solution for parenteral formulationNAKAMURA, Katsutoshi; TANAKA, Tomonari; SAITO, Katsumi et al.International journal of pharmaceutics. 2001, Vol 222, Num 1, pp 91-99, issn 0378-5173Article

Failure of stability prediction for minodronic acid injectable by accelerated stability testingNAKAMURA, Katsutoshi; YOKOHAMA, Shigeharu; SONOBE, Takashi et al.International journal of pharmaceutics. 2002, Vol 241, Num 1, pp 65-71, issn 0378-5173Article

Effect of combination therapy with a novel bisphosphonate, minodronate (YM529), and docetaxel on a model of bone metastasis by human transitional cell carcinomaINOUE, Keiji; KARASHIMA, Takashi; FUKATA, Satoshi et al.Clinical cancer research. 2005, Vol 11, Num 18, pp 6669-6677, issn 1078-0432, 9 p.Article

Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signalingYAMAGISHI, Sho-Ichi; ABE, Riichiro; BUCALA, Richard et al.The American journal of pathology. 2004, Vol 165, Num 6, pp 1865-1874, issn 0002-9440, 10 p.Article

Nitrogen-containing bisphosphonate, YM529/ONO-5920, inhibits macrophage inflammatory protein 1α expression and secretion in mouse myeloma cellsTSUBAKI, Masanobu; KATO, Chisato; NISHINOBO, Minori et al.Cancer science. 2008, Vol 99, Num 1, pp 152-158, issn 1347-9032, 7 p.Article

Effect of daily oral minodronate on vertebral fractures in Japanese postmenopausal women with established osteoporosis: a randomized placebo-controlled double-blind studyMATSUMOTO, T; HAGINO, H; SHIRAKI, M et al.Osteoporosis international. 2009, Vol 20, Num 8, pp 1429-1437, issn 0937-941X, 9 p.Article

The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-lnduced invasion in prostate cancerMIWA, Sotaro; MIZOKAMI, Atsushi; KELLER, Evan T et al.Cancer research (Baltimore). 2005, Vol 65, Num 19, pp 8818-8825, issn 0008-5472, 8 p.Article

Effect of minodronic acid (ONO-5920) on bone mineral density and arthritis in adult rats with collagen-induced arthritisYAMANE, Itsuro; HAGINO, Hiroshi; OKANO, Toru et al.Arthritis and rheumatism. 2003, Vol 48, Num 6, pp 1732-1741, issn 0004-3591, 10 p.Article

Combined therapy with a new bisphosphonate, minodronate (YM529), and chemotherapy for multiple organ metastases of small cell Lung cancer cells in severe Combined immunodeficient miceYANO, Seiji; HELONG ZHANG; HANIBUCHI, Masaki et al.Clinical cancer research. 2003, Vol 9, Num 14, pp 5380-5385, issn 1078-0432, 6 p.Article

Computational Insights into Binding of Bisphosphates to Farnesyl Pyrophosphate SynthaseOHNO, K; MORI, K; ORITA, M et al.Current medicinal chemistry. 2011, Vol 18, Num 2, pp 220-233, issn 0929-8673, 14 p.Article

Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathwayTSUBAKI, Masanobu; SATOU, Takao; ITOH, Tatsuki et al.Toxicology and applied pharmacology. 2012, Vol 259, Num 3, pp 402-410, issn 0041-008X, 9 p.Article

Synthesis, stereochemistry and SAR of a series of minodronate analogues as RGGT inhibitorsBLAZEWSKA, Katarzyna M; NI, Feng; MCKENNA, Charles E et al.European journal of medicinal chemistry. 2011, Vol 46, Num 10, pp 4820-4826, issn 0223-5234, 7 p.Article

Efficacy of a nitrogen-containing bisphosphonate, minodronate, in conjunction with a p38 mitogen activated protein kinase inhibitor or doxorubicin against malignant bone tumor cellsKUBO, Tadahiko; SHIMOSE, Shoji; MATSUO, Toshihiro et al.Cancer chemotherapy and pharmacology. 2008, Vol 62, Num 1, pp 111-116, issn 0344-5704, 6 p.Article