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Results 1 to 25 of 710

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Effects of Panax notoginseng saponin on α, β, and γ secretase involved in Aβ deposition in SAMP8 miceJINLAN HUANG; DENGPAN WU; JINSHENG WANG et al.Neuroreport (Oxford). 2014, Vol 25, Num 2, pp 89-93, issn 0959-4965, 5 p.Article

Guinea pigs as a nontransgenic model for APP processing in vitro and in vivoBECK, Mike; BIGL, Volker; ROSSNER, Steffen et al.Neurochemical research. 2003, Vol 28, Num 3-4, pp 637-644, issn 0364-3190, 8 p.Article

Conformational transition in the substrate binding domain of β-secretase exploited by NMA and its implication in inhibitor recognition: BACE1-myricetin a case studyCHAKRABORTY, Sandipan; KUMAR, Sanjay; BASU, Soumalee et al.Neurochemistry international. 2011, Vol 58, Num 8, pp 914-923, issn 0197-0186, 10 p.Article

Inhibition of angiogenesis and tumor growth by β and γ-secretase inhibitorsPARIS, Daniel; QUADROS, Amita; PATEL, Nikunj et al.European journal of pharmacology. 2005, Vol 514, Num 1, pp 1-15, issn 0014-2999, 15 p.Article

Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's diseaseJO, Dong-Gyu; ARUMUGAM, Thiruma V; CAMANDOLA, Simonetta et al.Neurobiology of aging. 2010, Vol 31, Num 6, pp 917-925, issn 0197-4580, 9 p.Article

A β-Secretase (BACE1)-inhibiting C-Methylrotenoid Induced by Yeast Elicitation in Abronia nana Suspension CulturesKIM, Sang-In; YANG, Eun-Ju; PARK, Se-Hoon et al.Applied biochemistry and biotechnology. 2014, Vol 172, Num 7, pp 3529-3537, issn 0273-2289, 9 p.Article

Characterization of a new antidementia β-secretase inhibitory peptide from Saccharomyces cerevisiaeLEE, Dae-Hyoung; LEE, Dae-Hyung; LEE, Jong-Soo et al.Enzyme and microbial technology. 2007, Vol 42, Num 1, pp 83-88, issn 0141-0229, 6 p.Article

Disposition and Metabolism of Semagacestat, a γ-Secretase Inhibitor, in HumansPING YI; HADDEN, Chad; KULANTHAIVEL, Palaniappan et al.Drug metabolism and disposition. 2010, Vol 38, Num 4, pp 554-565, issn 0090-9556, 12 p.Article

Enhanced β-secretase processing alters APP axonal transport and leads to axonal defectsRODRIGUES, Elizabeth M; WEISSMILLER, April M; GOLDSTEIN, Lawrence S. B et al.Human molecular genetics (Print). 2012, Vol 21, Num 21, pp 4587-4601, issn 0964-6906, 15 p.Article

A γ-Secretase Inhibitor Decreases Amyloid-β Production in the Central Nervous SystemBATEMAN, Randall J; SIEMERS, Eric R; PAUL, Steven M et al.Annals of neurology. 2009, Vol 66, Num 1, pp 48-54, issn 0364-5134, 7 p.Article

Association of Omi/HtrA2 with γ-secretase in mitochondriaBEHBAHANI, Homira; PAVLOV, Pavel F; WIEHAGER, Birgitta et al.Neurochemistry international. 2010, Vol 57, Num 6, pp 668-675, issn 0197-0186, 8 p.Article

Modeling the binding affinities of β-secretase inhibitors: application to subsite specificityRAJAMANI, Ramkumar; REYNOLDS, Charles H.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 19, pp 4843-4846, issn 0960-894X, 4 p.Article

Alzheimer's secretases regulate voltage-gated sodium channelsKOVACS, Dora M; GERSBACHER, Manuel T; DOO YEON KIM et al.Neuroscience letters. 2010, Vol 486, Num 2, pp 68-72, issn 0304-3940, 5 p.Article

Interactions between the amyloid and cholinergic mechanisms in Alzheimer's diseasePAKASKI, Magdolna; KALMAN, Janos.Neurochemistry international. 2008, Vol 53, Num 5, pp 103-111, issn 0197-0186, 9 p.Article

Pathogenic mechanisms in Alzheimer's diseasePASTORINO, Lucia; KUN PING LU.European journal of pharmacology. 2006, Vol 545, Num 1, pp 29-38, issn 0014-2999, 10 p.Article

A novel pathway for amyloid precursor protein processingPORTELIUS, Erik; PRICE, Eric; BRINKMALM, Gunnar et al.Neurobiology of aging. 2011, Vol 32, Num 6, pp 1090-1098, issn 0197-4580, 9 p.Article

Novel α-secretase cleavage of Alzheimer's amyloid β precursor protein in the endoplasmic reticulum of COS7 cellsSHIN, Ryong-Woon; SAIDO, Takaomi C; MAEDA, Masahiro et al.Neuroscience letters. 2005, Vol 376, Num 1, pp 14-19, issn 0304-3940, 6 p.Article

Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilinCHIANG, Po-Min; FORTNA, RyanR; PRICE, DonaldL et al.Neurobiology of aging. 2012, Vol 33, Num 2, pp 277-285, issn 0197-4580, 9 p.Article

A novel approach to identifying β-secretase inhibitors : Bis-statine peptide mimetics discovered using structure and spot synthesisBRIDGES, Kristie Grove; CHOPRA, Rajiv; ANNIS-FREEMAN, Bethany et al.Peptides (New York, NY. 1980). 2006, Vol 27, Num 7, pp 1877-1885, issn 0196-9781, 9 p.Article

Effects of anoxia and hypoxia on amyloid precursor protein processing in cerebral microvascular smooth muscle cellsAUERBACH, Ilene D; VINTERS, Harry V.Journal of neuropathology and experimental neurology. 2006, Vol 65, Num 6, pp 610-620, issn 0022-3069, 11 p.Article

Virtual screening for β-secretase (BACE1) inhibitors reveals the importance of protonation states at Asp32 and Asp228POLGAR, Timea; KESERÜ, György M.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 11, pp 3749-3755, issn 0022-2623, 7 p.Article

A new wrestler in the battle between α- and β-secretases for cleavage of APPNEVE, Rachael L.Trends in neurosciences (Regular edition). 2003, Vol 26, Num 9, pp 461-463, issn 0166-2236, 3 p.Article

Elevated platelet β-secretase activity in mild cognitive impairmentLIU, W. W; TODD, S; CRAIG, D et al.Dementia and geriatric cognitive disorders. 2007, Vol 24, Num 6, pp 464-468, issn 1420-8008, 5 p.Article

Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1 (BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis : SPECIAL ISSUE: THE NEUROBIOLOGY OF AGING AND ALZHEIMER'S DISEASEYU DENG; ZHE WANG; RUITAO WANG et al.European journal of neuroscience (Print). 2013, Vol 37, Num 11-12, pp 1962-1969, issn 0953-816X, 8 p.Article

BACE2 plays a role in the insulin receptor trafficking in pancreatic β-cellsCASAS, Silvia; CASINI, Paola; PIQUER, Sandra et al.American journal of physiology. Endocrinology and metabolism. 2010, Vol 62, Num 6, issn 0193-1849, E1087-E1095Article

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