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Results 1 to 25 of 3205

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Intérêt de l'EMG dynamique dans le suivi des polyneuropathies dysimmunes chroniques = Interest of dynamic electromyography in the follow up of CIDPCINTAS, P.Revue neurologique (Paris). 2013, Vol 169, Num 12, pp 978-983, issn 0035-3787, 6 p.Conference Paper

NP TLC DATA IN STRUCTURE-ACTIVITY RELATIONSHIP STUDY OF SELECTED COMPOUNDS WITH ACTIVITY ON DOPAMINERGIC, SEROTONINERGIC, AND MUSCARINIC RECEPTORSZYDEK, Graiyna; BRZEZINSKA, Elżbieta.Journal of liquid chromatography & related technologies. 2012, Vol 35, Num 5-8, pp 834-853, issn 1082-6076, 20 p.Article

Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage—Preparation, in vitro screening and molecular dockingMUSILEK, Kamil; KOMLOOVA, Marketa; HOLAS, Ondrej et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 2, pp 754-762, issn 0968-0896, 9 p.Article

Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors: Analogues of SAD-128MUSILEK, Kamil; RODER, Jan; KOMLOOVA, Marketa et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 1, pp 150-154, issn 0960-894X, 5 p.Article

Synthesis and biological activity of a novel class nicotinic acetylcholine receptors (nAChRs) ligands structurally related to anatoxin-aSIMONI, Daniele; RONDANIN, Riccardo; VIRGINIO, Caterina et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 18, pp 5423-5427, issn 0960-894X, 5 p.Article

Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): The development of ML169, an MLPCN probeREID, Paul R; BRIDGES, Thomas M; CONN, P. Jeffrey et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 9, pp 2697-2701, issn 0960-894X, 5 p.Article

Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesteraseBHARATE, Sandip B; LILU GUO; REEVES, Tony E et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 2, pp 787-794, issn 0968-0896, 8 p.Article

Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M5 PAMBRIDGES, Thomas M; KENNEDY, J. Phillip; CHO, Hyekyung P et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 2, pp 558-562, issn 0960-894X, 5 p.Article

In silico characterization of cytisinoids docked into an acetylcholine binding proteinABIN-CARRIQUIRY, Juan Andrés; PAULINO ZUNINI, Margot; CASSELS, Bruce K et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 12, pp 3683-3687, issn 0960-894X, 5 p.Article

Synthesis and SAR of N-(4-(4-alklylpiperazin-1-yl)phenyl)benzamides as muscarinic acetylcholine receptor subtype 1 (M1) anatgonistsMILLER, Nicole R; DANIELS, R. Nathan; LEE, David et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 7, pp 2174-2177, issn 0960-894X, 4 p.Article

Discovery of novel α7 nicotinic receptor antagonistsYOUYI PENG; QIANG ZHANG; SNYDER, Gretchen L et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 16, pp 4825-4830, issn 0960-894X, 6 p.Article

Identification of 9-fluoro substituted (-)-cytisine derivatives as ligands with high affinity for nicotinic receptorsHOULLIER, Nicolas; GOPISETTI, Jaganmohan; LESTAGE, Pierre et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 22, pp 6667-6670, issn 0960-894X, 4 p.Article

N-Heterocyclic derived M1 positive allosteric modulatorsKUDUK, Scott D; DI MARCO, Christina N; THOMPSON, Charles D et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 4, pp 1334-1337, issn 0960-894X, 4 p.Article

Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitorsLING HUANG; ANDING SHI; FENG HE et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 3, pp 1244-1251, issn 0968-0896, 8 p.Article

3D-QSAR studies of 2,2-diphenylpropionates to aid discovery of novel potent muscarinic antagonistsBHATTACHARJEE, Apurba K; GORDON, Jonathan A; MAREK, Elizabeth et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 11, pp 3999-4012, issn 0968-0896, 14 p.Article

Design, Synthesis, and Structure-Activity Relationship of Tropane Muscarinic Acetylcholine Receptor AntagonistsLAINE, Dramane I; ZEHONG WAN; BLANEY, Frank E et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 16, pp 5241-5252, issn 0022-2623, 12 p.Article

Fluorinated pyridinium oximes as potential reactivators for acetylcholinesterases inhibited by paraoxon organophosphorus agentHEE CHUN JEONG; PARK, No-Joong; CHONG HAK CHAE et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 17, pp 6213-6217, issn 0968-0896, 5 p.Article

Structure and Activity of (2,8)-Dicarba-(3,12)-cystino α-ImI, an α-Conotoxin Containing a Nonreducible Cystine AnalogueMACRAILD, Christopher A; ILLESINGHE, Jayamini; VAN LIEROP, Bianca J et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 3, pp 755-762, issn 0022-2623, 8 p.Article

Use of Acetylcholine Binding Protein in the Search for Novel a7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray AnalysisULENS, Chris; AKDEMIR, Atilla; DE ESCH, Iwan J. P et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 8, pp 2372-2383, issn 0022-2623, 12 p.Article

Design of novel α7-subtype-preferring nicotinic acetylcholine receptor agonists: Application of docking and MM-PBSA computational approaches, synthetic and pharmacological studiesGRAZIOSO, Giovanni; DIEGO YURI POME; CARLO MATERA et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 22, pp 6353-6357, issn 0960-894X, 5 p.Article

Current Clinical Applications of Botulinum ToxinTRUONG, Daniel D; STENNER, Andrea; REICHEL, Gerhard et al.Current pharmaceutical design (Print). 2009, Vol 15, Num 31, pp 3671-3680, issn 1381-6128, 10 p.Article

Muscarinic receptor 1 agonist activity of novel N-aryl carboxamide substituted 3-morpholino arecoline derivatives in Alzheimer's presenile dementia modelsMALVIYA, Manish; SUNIL KUMAR, Y. C; MYTHRI, R. B et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 15, pp 5526-5534, issn 0968-0896, 9 p.Article

Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates ― subtype selective, high affinity α7 nicotinic acetylcholine receptor agonistsO'DONNELL, Christopher J; LANGU PENG; O'NEILL, Brian T et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 16, pp 4747-4751, issn 0960-894X, 5 p.Article

Avertissement à propos de la varénicline : risque versus bénéfice = About varenicline : risk versus benefitThe Medical letter on drugs and therapeutics (Edition française). 2008, Vol 30, Num 16, pp 61-61, issn 0253-8512, 1 p.Article

Discovery of Novel and Long Acting Muscarinic Acetylcholine Receptor AntagonistsJIAN JIN; YONGHUI WANG; BERLANGA, Manuela et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 16, pp 4866-4869, issn 0022-2623, 4 p.Article

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