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Results 1 to 25 of 1210

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Organotypic Cultures as Tools for Testing Neuroactive Drugs - Link Between In-Vitro and In-Vivo ExperimentsDREXLER, B; HENTSCHKE, H; ANTKOWIAK, B et al.Current medicinal chemistry. 2010, Vol 17, Num 36, pp 4538-4550, issn 0929-8673, 13 p.Article

Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO)REYNOLDS, Aaron; HANANI, Raphy; HIBBS, David et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 19, pp 5799-5802, issn 0960-894X, 4 p.Article

Allopregnanolone (3α-Hydroxy-5a-pregnan-20-one) Derivatives with a Polar Chain in Position 16a : Synthesis and ActivitySLAVIKOVA, Barbora; KRISTOFIKOVA, Zdena; CHODOUNSKA, Hana et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 7, pp 2119-2125, issn 0022-2623, 7 p.Article

Single-Step High-Yield Radiosynthesis and Evaluation of a Sensitive 18F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PETBRIARD, Emmanuelle; ZOGHBI, Sami S; SIMEON, Fabrice G et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 3, pp 688-699, issn 0022-2623, 12 p.Article

Neurosteroid Analogues. 14. Alternative Ring System Scaffolds : GABA Modulatory and Anesthetic Actions of Cyclopenta[b]phenanthrenes and Cyclopenta[b]anthracenesSCAGLIONE, Jamie B; JASTRZEBSKA, Izabella; ZORUMSKI, Charles F et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 5, pp 1309-1318, issn 0022-2623, 10 p.Article

Synthesis and GABAA receptor activity of oxygen-bridged neurosteroid analogsALVAREZ, Lautaro D; VELEIRO, Adriana S; BAGGIO, Ricardo F et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 7, pp 3831-3838, issn 0968-0896, 8 p.Article

A study of the structure-activity relationship of GABAA-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysisDONGMEI HAN; HOLGER FÖRSTERLING, F; SANKAR, Subramaniam et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 19, pp 8853-8862, issn 0968-0896, 10 p.Article

Synthesis, 3D-QSAR, and docking studies of 1 -phenyl -1H-1,2,3 -triazoles as selective antagonists for β3 over α1β2γ2 GABA receptorsMOHAMMAD SAYED ALAM; JIA HUANG; OZOE, Fumiyo et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 15, pp 5090-5104, issn 0968-0896, 15 p.Article

Complex dosing schedules for continuous intrathecal baclofen infusionKRACH, Linda E; KRIEL, Robert L; NUGENT, Andrea C et al.Pediatric neurology. 2007, Vol 37, Num 5, pp 354-359, issn 0887-8994, 6 p.Article

Channel-like functions of the 18-kDa translocator protein (TSPO) : Regulation of apoptosis and steroidogenesis as part of the host-defense responseVEENMAN, Leo; PAPADOPOULOS, Vassilios; GAVISH, Moshe et al.Current pharmaceutical design. 2007, Vol 13, Num 23, pp 2385-2405, issn 1381-6128, 21 p.Article

Novel 3 -iodo -8 -ethoxypyrazolo [5,1-c][1,2,4 ]benzotriazine 5-oxide as promising lead for design of α5-inverse agonist useful tools for therapy of mnemonic damageGUERRINI, Gabriella; CICIANI, Giovanna; COSTANZO, Annarella et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 7, pp 2573-2586, issn 0968-0896, 14 p.Article

Analgesic addiction and pseudoaddiction in painful chronic illnessLUSHER, Joanne; ELANDER, James; BEVAN, David et al.The Clinical journal of pain. 2006, Vol 22, Num 3, pp 316-324, issn 0749-8047, 9 p.Article

Midazolam disrupts fear memory reconsolidationBUSTOS, S. G; MALDONADO, H; MOLINA, V. A et al.Neuroscience. 2006, Vol 139, Num 3, pp 831-842, issn 0306-4522, 12 p.Article

Un nouveau rôle pour le récepteur périphérique des benzodiazépines? = A new role for peripheral benzodiazepine receptor?OSTUNI, Mariano A; LACAPERE, Jean-Jacques.MS. Médecine sciences. 2005, Vol 21, Num 3, pp 240-242, issn 0767-0974, 3 p.Article

Comparison of midazolam effects on inhibitory postsynaptic currents in hippocampal CA3 with those in CAIKOBAYASHI, Suguru; FUJITO, Yutaka; MATSUYAMA, Kiyoji et al.Neuroreport (Oxford). 2005, Vol 16, Num 9, pp 1003-1007, issn 0959-4965, 5 p.Article

Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligandsTRAPANI, Giuseppe; LAQUINTANA, Valentino; SANNA, Enrico et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 1, pp 292-305, issn 0022-2623, 14 p.Article

Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoromethoxy-d2-5-methoxybenzyl)acetamide : a deuterium-substituted radioligand for peripheral benzodiazepine receptorZHANG, Ming-Rong; MAEDA, Jun; ITO, Takehito et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 5, pp 1811-1818, issn 0968-0896, 8 p.Article

Multiple sclerosis : novel perspectives on newly forming lesionsMATUTE, Carlos; PEREZ-CERDA, Fernando.Trends in neurosciences (Regular edition). 2005, Vol 28, Num 4, pp 173-175, issn 0166-2236, 3 p.Article

7-(1,1-dimethylethyl)-6-(2-ethyl-2h-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine : A functionally selective γ-aminobutyric AcidA (GABAA) α2/α3-subtype selective agonist that exhibits potent anxiolytic activity but is not sedating in animal modelsCARLING, Robert W; MADIN, Andrew; MCKERNAN, Ruth M et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 23, pp 7089-7092, issn 0022-2623, 4 p.Article

Delayed complications of discontinuation of intrathecal baclofen therapy: resurgence of dyssynergic voiding, which triggered off autonomic dysreflexia and hydronephrosisVAIDYANATHAN, S; SONIC, B. M; OO, T et al.Spinal cord. 2004, Vol 42, Num 10, pp 598-602, issn 1362-4393, 5 p.Article

GABA receptor antagonists and insecticides: common structural features of 4-alkyl-1-phenylpyrazoles and 4-alkyl-1-phenyltrioxabicyclooctanesSAMMELSON, Robert E; CABONI, Pierluigi; DURKIN, Kathleen A et al.Bioorganic & medicinal chemistry. 2004, Vol 12, Num 12, pp 3345-3355, issn 0968-0896, 11 p.Article

Development of effective therapeutics targeting the GABAA receptor: Naturally occurring alternatives : Computational biology and drug designTSANG, S. Y; XUE, H.Current pharmaceutical design. 2004, Vol 10, Num 9, pp 1035-1044, issn 1381-6128, 10 p.Article

Dye-labeled benzodiazepines: Development of small ligands for receptor binding studies using fluorescence correlation spectroscopyHEGENER, Oliver; JORDAN, Randolf; HÄBERLEIN, Hanns et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 14, pp 3600-3605, issn 0022-2623, 6 p.Article

Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazin es and analogues as subtype-selective inverse agonists for the GABAAα5 benzodiazepine binding siteSTREET, Leslie J; STERNFELD, Francine; DAWSON, Gerard R et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 14, pp 3642-3657, issn 0022-2623, 16 p.Article

Association of GRIP1 with a GABAA receptor associated protein suggests a role for GRIP1 at inhibitory synapsesKITTLER, Josef T; ARANCIBIA-CARCAMO, I. Lorena; MOSS, Stephen J et al.Biochemical pharmacology. 2004, Vol 68, Num 8, pp 1649-1654, issn 0006-2952, 6 p.Conference Paper

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