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Temporal and spatial regulation of cAMP signaling in disease: role of cyclic nucleotide phosphodiesterasesOTERO, Carolina; PENALOZA, Juan P; RODAS, Paula I et al.Fundamental & clinical pharmacology. 2014, Vol 28, Num 6, pp 593-607, issn 0767-3981, 15 p.Article

Quality-improvement analytics for intravenous infusion pumpsSKLEDAR, Susan J; NICCOLAI, Cynthia S; SCHILLING, Dennis et al.American journal of health-system pharmacy. 2013, Vol 70, Num 8, pp 680-686, issn 1079-2082, 7 p.Article

Senescent Cells: A Novel Therapeutic Target for Aging and Age-Related DiseasesNAYLOR, R. M; BAKER, D. J; DEURSEN, Jm Van et al.Clinical pharmacology and therapeutics. 2013, Vol 93, Num 1, pp 105-116, issn 0009-9236, 12 p.Article

1,4―Diarylpiperazines and analogs as anti-tubercular agents: Synthesis and biological evaluationFORGE, D; CAPPOEN, D; LAURENT, J et al.European journal of medicinal chemistry. 2012, Vol 49, pp 95-101, issn 0223-5234, 7 p.Article

1-(2-Mercaptobenzenesulfonyl)-3-hydroxyguanidines ― Novel potent antiproliferatives, synthesis and in vitro biological activityBROZEWICZ, Kamil; SLAWINSKI, Jarosław.European journal of medicinal chemistry. 2012, Vol 55, pp 384-394, issn 0223-5234, 11 p.Article

3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: Molecular modeling and pharmacological studiesCOLOTTA, Vittoria; LENZI, Ombretta; COPPI, Elisabetta et al.European journal of medicinal chemistry. 2012, Vol 54, pp 470-482, issn 0223-5234, 13 p.Article

A novel class of small-molecule caspase-3 inhibitors prepared by multicomponent reactionsQIUHUA ZHU; LIXIN GAO; ZHIPENG CHEN et al.European journal of medicinal chemistry. 2012, Vol 54, pp 232-238, issn 0223-5234, 7 p.Article

Amino acid, dipeptide and pseudodipeptide conjugates of ring-substituted 8-aminoquinolines: Synthesis and evaluation of anti-infective, β-haematin inhibition and cytotoxic activitiesKAUR, Kirandeep; JAIN, Meenakshi; KHAN, Shabana I et al.European journal of medicinal chemistry. 2012, Vol 52, pp 230-241, issn 0223-5234, 12 p.Article

Antiproliferative effect of novel platinum(II) and palladium(II) complexes on hepatic tumor stem cells in vitroMIKLASOVA, Natalia; FISCHER-FODOR, Eva; LÖNNECKE, Peter et al.European journal of medicinal chemistry. 2012, Vol 49, pp 41-47, issn 0223-5234, 7 p.Article

Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): A search for new dual-acting agents as potential antidepressantsZHU, Xue Y; ETUKALA, Jagan R; EYUNNI, Suresh V. K et al.European journal of medicinal chemistry. 2012, Vol 53, pp 124-132, issn 0223-5234, 9 p.Article

Biomimetic in vitro oxidation of lapachol: A model to predict and analyse the in vivo phase I metabolism of bioactive compoundsNIEHUES, Michael; PRISCILA BARROS, Valeria; DA SILVA EMERY, Flávio et al.European journal of medicinal chemistry. 2012, Vol 54, pp 804-812, issn 0223-5234, 9 p.Article

Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activityCHEN, Kuen-Feng; TAI, Wei-Tien; HSU, Cheng-Yi et al.European journal of medicinal chemistry. 2012, Vol 55, pp 220-227, issn 0223-5234, 8 p.Article

Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agentsMENENDEZ, Christophe; CHOLLET, Aurelien; RODRIGUEZ, Frederic et al.European journal of medicinal chemistry. 2012, Vol 52, pp 275-283, issn 0223-5234, 9 p.Article

Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitorsGU, Shuang-Xi; LI, Zhi-Ming; MA, Xiao-Dong et al.European journal of medicinal chemistry. 2012, Vol 53, pp 229-234, issn 0223-5234, 6 p.Article

Converting Peptides into Drug Leads by LipidationZHANG, L; BULAJ, G.Current medicinal chemistry. 2012, Vol 19, Num 11, pp 1602-1618, issn 0929-8673, 17 p.Article

Design and synthesis of novel 5-phenyl-N-piperidine ethanone containing 4,5-dihydropyrazole derivatives as potential antitumor agentsLIU, Xin-Hua; JUN LI; SHI, Jing Bo et al.European journal of medicinal chemistry. 2012, Vol 51, pp 294-299, issn 0223-5234, 6 p.Article

Design and synthesis of peptides from bacterial ParE toxin as inhibitors of topoisomerasesBERTUCCI BARBOSA, Luiz Carlos; SANTESSO GARRIDO, Saulo; GARCIA, Anderson et al.European journal of medicinal chemistry. 2012, Vol 54, pp 591-596, issn 0223-5234, 6 p.Article

Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrasesCAPKAUSKAITE, Edita; ZUBRIENE, Asta; BARANAUSKIENE, Lina et al.European journal of medicinal chemistry. 2012, Vol 51, pp 259-270, issn 0223-5234, 12 p.Article

Design, synthesis, and structure—activity relationship studies of novel millepachine derivatives as potent antiproliferative agentsGUANGCHENG WANG; WENSHUANG WU; JINGXIANG QIU et al.European journal of medicinal chemistry. 2012, Vol 54, pp 793-803, issn 0223-5234, 11 p.Article

Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimizationYANG, Ling-Ling; LI, Guo-Bo; YAN, Heng-Xiu et al.European journal of medicinal chemistry. 2012, Vol 56, pp 30-38, issn 0223-5234, 9 p.Article

Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5-yl) thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraineANNEDI, Subhash C; MADDAFORD, Shawn P; DONGQIN ZHANG et al.European journal of medicinal chemistry. 2012, Vol 55, pp 94-107, issn 0223-5234, 14 p.Article

Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitorsDE OLIVEIRA LOPES, Raquel; CORREIA ROMEIRO, Nelilma; DE LIMA, Cleverton Kleiton F et al.European journal of medicinal chemistry. 2012, Vol 54, pp 264-271, issn 0223-5234, 8 p.Article

Drugs for stroke: Action of nitrone (Z)-N-(2-bromo-5-hydroxy-4-methoxybenzylidene)-2-methylpropan-2-amine oxide on rat cortical neurons in culture subjected to oxygen―glucose-deprivationARCE, Carmen; DIAZ-CASTROVERDE, Sabela; CANALES, María J et al.European journal of medicinal chemistry. 2012, Vol 55, pp 475-479, issn 0223-5234, 5 p.Article

Efficient synthesis and anti-enteroviral activity of 9-arylpurinesAGUADO, Leire; CANELA, María-Dolores; JAN THIBAUT, Hendrik et al.European journal of medicinal chemistry. 2012, Vol 49, pp 279-288, issn 0223-5234, 10 p.Article

Enhanced cellular uptake and in vitro antitumor activity of short-chain fatty acid acylated daunorubicin―GnRH-III bioconjugatesHEGEDÜS, Rózsa; MANEA, Marilena; ORBAN, Erika et al.European journal of medicinal chemistry. 2012, Vol 56, pp 155-165, issn 0223-5234, 11 p.Article

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