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A Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3AYUPING CHEN; SKILES, Gary L; SHOU, Magang et al.Drug metabolism and disposition. 2011, Vol 39, Num 9, pp 1668-1673, issn 0090-9556, 6 p.Article

ATP-Binding Cassette Transporter Expression in Human Placenta as a Function of Pregnancy ConditionMASON, Cifford W; BUHIMSCHI, Irina A; BUHIMSCHI, Catalin S et al.Drug metabolism and disposition. 2011, Vol 39, Num 6, pp 1000-1007, issn 0090-9556, 8 p.Article

Attenuation of Intestinal Absorption by Major Efflux Transporters: Quantitative Tools and Strategies Using a Caco-2 ModelXUENA LIN; SKOLNIK, Suzanne; XIAOHUI CHEN et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 265-274, issn 0090-9556, 10 p.Article

CYP2G2, Pseudogenized in Human, Is Expressed in Nasal Mucosa of Cynomolgus Monkey and Encodes a Functional Drug-Metabolizing EnzymeUNO, Yasuhiro; UEHARA, Shotaro; MURAYAMA, Norie et al.Drug metabolism and disposition. 2011, Vol 39, Num 4, pp 717-723, issn 0090-9556, 7 p.Article

Development of a Highly Sensitive Cytotoxicity Assay System for CYP3A4-Mediated Metabolic ActivationHOSOMI, Hiroko; FUKAMI, Tatsuki; IWAMURA, Atsushi et al.Drug metabolism and disposition. 2011, Vol 39, Num 8, pp 1388-1395, issn 0090-9556, 8 p.Article

Disposition and Metabolism of [14C]SB-649868, an Orexin 1 and 2 Receptor Antagonist, in HumansRENZULLI, Cecilia; NASH, Mike; WRIGHT, Mark et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 215-227, issn 0090-9556, 13 p.Article

Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-FluorouracilNAMBARU, Praveen K; HÜBNER, Tobias; ROSSKOPF, Dieter et al.Drug metabolism and disposition. 2011, Vol 39, Num 1, pp 132-139, issn 0090-9556, 8 p.Article

Effect of Estradiol on Gene Expression Profile in Cynomolgus Macaque Liver: Implications for Drug-Metabolizing EnzymesUNO, Yasuhiro; KITO, Go.Drug metabolism and disposition. 2011, Vol 39, Num 11, pp 2003-2007, issn 0090-9556, 5 p.Article

Effects of Chronic Renal Failure on Kidney Drug Transporters and Cytochrome P450 in RatsNAUD, Judith; MICHAUD, Josee; BEAUCHEMIN, Stephanie et al.Drug metabolism and disposition. 2011, Vol 39, Num 8, pp 1363-1369, issn 0090-9556, 7 p.Article

Effects of Interleukin-6 (IL-6) and an Anti-IL-6 Monoclonal Antibody on Drug-Metabolizing Enzymes in Human Hepatocyte CultureDICKMANN, Leslie J; PATEL, Sonal K; ROCK, Dan A et al.Drug metabolism and disposition. 2011, Vol 39, Num 8, pp 1415-1422, issn 0090-9556, 8 p.Article

Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux MechanismsZHEN YANG; SONG GAO; JINGRONG WANG et al.Drug metabolism and disposition. 2011, Vol 39, Num 10, pp 1866-1872, issn 0090-9556, 7 p.Article

Gestation Time-Dependent Pharmacokinetics of Intravenous (+)-Methamphetamine in RatsWHITE, Sarah; LAURENZANA, Elizabeth; HENDRICKSON, Howard et al.Drug metabolism and disposition. 2011, Vol 39, Num 9, pp 1718-1726, issn 0090-9556, 9 p.Article

Glutaredoxin and Thioredoxin Can Be Involved in Producing the Pharmacologically Active Metabolite of a Thienopyridine Antiplatelet Agent, PrasugrelHAGIHARA, Katsunobu; KAZUI, Miho; KURIHARA, Atsushi et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 208-214, issn 0090-9556, 7 p.Article

Histone Deacetylase Inhibitors Increase Human Arylamine N-Acetyltransferase-1 Expression in Human Tumor CellsPATERSON, Scott; SIN, Kok L; TIANG, Jacky M et al.Drug metabolism and disposition. 2011, Vol 39, Num 1, pp 77-82, issn 0090-9556, 6 p.Article

Human CYP2S1 Metabolizes Cyclooxygenase- and Lipoxygenase-Derived EicosanoidsSBUI, Peter; IMAIZUMI, Satoshi; REDDY BEEDANAGARI, Sudheer et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 180-190, issn 0090-9556, 11 p.Article

Identification of Human Liver Cytochrome P450 Enzymes Involved in the Metabolism of SCH 530348 (Vorapaxar), a Potent Oral Thrombin Protease-Activated Receptor 1 AntagonistGHOSAL, Anima; XIAOWEN LU; PENNER, Natalia et al.Drug metabolism and disposition. 2011, Vol 39, Num 1, pp 30-38, issn 0090-9556, 9 p.Article

In Vitro Metabolism of Irosustat, a Novel Steroid Sulfatase Inhibitor: Interspecies Comparison, Metabolite Identification, and Metabolic Enzyme IdentificationVENTURA, Veronica; SOLA, Josep; CELMA, Carles et al.Drug metabolism and disposition. 2011, Vol 39, Num 7, pp 1235-1246, issn 0090-9556, 12 p.Article

Influence of Drug Solubility and Lipophilicity on Transscieral Retinal Delivery of Six CorticosteroidsTHAKUR, Ashish; KADAM, Rajendra S; KOMPELLA, Uday B et al.Drug metabolism and disposition. 2011, Vol 39, Num 5, pp 771-781, issn 0090-9556, 11 p.Article

Interactions of Green Tea Catechins with Organic Anion-Transporting PolypeptidesROTH, Megan; TIMMERMANN, Barbara N; HAGENBUCH, Bruno et al.Drug metabolism and disposition. 2011, Vol 39, Num 5, pp 920-926, issn 0090-9556, 7 p.Article

Mechanisms of Reduced Maternal and Fetal Lopinavir Exposure in a Rat Model of Gestational DiabetesANGER, Gregory J; PIQUETTE-MILLER, Micheline.Drug metabolism and disposition. 2011, Vol 39, Num 10, pp 1850-1859, issn 0090-9556, 10 p.Article

Metabolic Pathways of the Camptothecin Analog AR-67HORN, Jamie; MILEWSKA, Marta; ARNOLD, Susanne M et al.Drug metabolism and disposition. 2011, Vol 39, Num 4, pp 683-692, issn 0090-9556, 10 p.Article

Metabolism and Disposition of Eltrombopag, an Oral, Nonpeptide Thrombopoietin Receptor Agonist, in Healthy Human SubjectsYANLI DENG; MADATIAN, Armina; GORYCKI, Peter D et al.Drug metabolism and disposition. 2011, Vol 39, Num 9, pp 1734-1746, issn 0090-9556, 13 p.Article

Metabolism of LY654322, a Growth Hormone Secretagogue, to an Unusual Diimidazopyridine MetaboliteBOREL, Anthony G; JONES, Timothy M; BARBUCH, Robert J et al.Drug metabolism and disposition. 2011, Vol 39, Num 5, pp 740-749, issn 0090-9556, 10 p.Article

Monoclonal Antibodies with Identical Fc Sequences Can Bind to FcRn Differentially with Pharmacokinetic ConsequencesWEIRONG WANG; PING LU; YULIN FANG et al.Drug metabolism and disposition. 2011, Vol 39, Num 9, pp 1469-1477, issn 0090-9556, 9 p.Article

Novel Cytochrome P450-Mediated Ring Opening of the 1,3,4-Oxadiazole in Setileuton, a 5-Lipoxygenase InhibitorMACIOLEK, Cheri M; MA, Bennett; MENZEL, Karsten et al.Drug metabolism and disposition. 2011, Vol 39, Num 5, pp 763-770, issn 0090-9556, 8 p.Article

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