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Results 1 to 25 of 5666

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12-N-Methylated 5,6-dihydrobenzo[c]acridine derivatives: A new class of highly selective ligands for c-myc G-quadruplex DNALIAO, Sheng-Rong; ZHOU, Chen-Xi; WU, Wei-Bin et al.European journal of medicinal chemistry. 2012, Vol 53, pp 52-63, issn 0223-5234, 12 p.Article

A SAR study on a series of synthetic lipophilic chalcones as Inhibitor of transcription factor NF-κBVENKATESWARARAO, Eeda; SHARMA, Vinay K; LEE, Ki-Cheul et al.European journal of medicinal chemistry. 2012, Vol 54, pp 379-386, issn 0223-5234, 8 p.Article

A new class of bioactivable self-immolative N,O-ligandsKUZNIK, Nikodem; CHROBACZYNSKI, Arkadiusz; MIKA, Małgorzata et al.European journal of medicinal chemistry. 2012, Vol 52, pp 184-192, issn 0223-5234, 9 p.Article

A series of 2-arylamino-5-(indolyl)-1,3,4-thiadiazoles as potent cytotoxic agentsKUMAR, Dalip; MARUTHI KUMAR, N; NOEL, Brett et al.European journal of medicinal chemistry. 2012, Vol 55, pp 432-438, issn 0223-5234, 7 p.Article

A solvent free, four-component synthesis and 1,3-dipolar cycloaddition of 4(H)-pyrans with nitrile oxides: Synthesis and discovery of antimycobacterial activity of enantiomerically pure 1,2,4-oxadiazolesALMANSOUR, Abdulrahman I; SURESH KUMAR, Raju; ARUMUGAM, Natarajan et al.European journal of medicinal chemistry. 2012, Vol 53, pp 416-423, issn 0223-5234, 8 p.Article

Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffoldKRATKY, Martin; VINSOVA, Jarmila; VOLKOVA, Marie et al.European journal of medicinal chemistry. 2012, Vol 50, pp 433-440, issn 0223-5234, 8 p.Article

Antiproliferative activity against human non-small cell lung cancer of two 0-alkyl-diglycosylglycerols from the marine sponges Myrmekioderma dendyi and Trikentrion laeveFAROKHI, Fereshteh; WIELGOSZ-COLLIN, Gaetane; ROBIC, Audrey et al.European journal of medicinal chemistry. 2012, Vol 49, pp 406-410, issn 0223-5234, 5 p.Article

Antitumor agents 292. Design, synthesis and pharmacological study of S- and 0-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agentsYING CHEN; LIM, Hong-Rui; MORRIS-NATSCHKE, Susan L et al.European journal of medicinal chemistry. 2012, Vol 49, pp 74-85, issn 0223-5234, 12 p.Article

Bone-targeting glycol and NSAIDS ester prodrugs of rhein: Synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studiesJIN CAI; YANBING DUAN; JIA YU et al.European journal of medicinal chemistry. 2012, Vol 55, pp 409-419, issn 0223-5234, 11 p.Article

Carnosine analogues containing NO-donor substructures: Synthesis, physico-chemical characterization and preliminary pharmacological profileBERTINARIA, Massimo; ROLANDO, Barbara; GIORGIS, Marta et al.European journal of medicinal chemistry. 2012, Vol 54, pp 103-112, issn 0223-5234, 10 p.Article

Design and synthesis of novel stiripentol analogues as potential anticonvulsantsABOUL-ENEIN, Mohamed N; EL-AZZOUNY, Aida A; ATTIA, Mohamed I et al.European journal of medicinal chemistry. 2012, Vol 47, pp 360-369, issn 0223-5234, 10 p.Article

Design, synthesis and anticancer activity of nitric oxide donating/chalcone hybridsMOURAD, Mai A. E; ABDEL-AZIZ, Mohamed; ABUO-RAHMA, Gamal El-Din A. A et al.European journal of medicinal chemistry. 2012, Vol 54, pp 907-913, issn 0223-5234, 7 p.Article

Design, synthesis and antiviral activity of novel pyridazinesZIWEN WANG; MINGXIAO WANG; XUE YAO et al.European journal of medicinal chemistry. 2012, Vol 54, pp 33-41, issn 0223-5234, 9 p.Article

Design, synthesis and biological evaluation of some novel thienopyrimidines and fused thienopyrimidines as anti-inflammatory agentsRIZK, Ola H; SHAABAN, Omaima G; EL-ASHMAWY, Ibrahim M et al.European journal of medicinal chemistry. 2012, Vol 55, pp 85-93, issn 0223-5234, 9 p.Article

Design, synthesis and evaluation of triazole functionalized ring-fused 2-pyridones as antibacterial agentsBENGTSSON, Christoffer; LINDGREN, Anders E. G; UVELL, Hanna et al.European journal of medicinal chemistry. 2012, Vol 54, pp 637-646, issn 0223-5234, 10 p.Article

Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agentsWANG, Li-Jun; GENG, Chang-An; MA, Yun-Bao et al.European journal of medicinal chemistry. 2012, Vol 54, pp 352-365, issn 0223-5234, 14 p.Article

Design, synthesis, antimicrobial, anti-inflammatory and analgesic activity of novel isoxazolyl pyrimido[4,5-b]quinolines and isoxazolyl chromeno[2,3-d] pyrimidin-4-onesRAJANARENDAR, E; NAGI REDDY, M; RAMA KRISHNA, S et al.European journal of medicinal chemistry. 2012, Vol 55, pp 273-283, issn 0223-5234, 11 p.Article

Design, synthesis, in vitro antimicrobial and anticancer activity of novel methylenebis-isoxazolo[4,5-b]azepines derivativesRAJANARENDAR, E; NAGI REDDY, M; RAMA KRISHNA, S et al.European journal of medicinal chemistry. 2012, Vol 50, pp 344-349, issn 0223-5234, 6 p.Article

Discovery of a new antileishmanial hit in 8-nitroquinoline seriesPALOQUE, Lucie; VERHAEGHE, Pierre; RAULT, Sylvain et al.European journal of medicinal chemistry. 2012, Vol 54, pp 75-86, issn 0223-5234, 12 p.Article

Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategyLIU, Ming-Ming; LU ZHOU; HE, Pei-Lan et al.European journal of medicinal chemistry. 2012, Vol 52, pp 33-43, issn 0223-5234, 11 p.Article

Discovery of non-oxime reactivators using an in silico pharmacophore model of oxime reactivators of OP-inhibited acetylcholinesteraseBHATTACHARJEE, Apurba K; MAREK, Elizabeth; HA THU LE et al.European journal of medicinal chemistry. 2012, Vol 49, pp 229-238, issn 0223-5234, 10 p.Article

Electrochemical and spectroscopic investigations of isoniazide and its analogs with ds.DNA at physiological pH: Evaluation of biological activitiesARSHAD, Nasima; YUNUS, Uzma; RAZZQUE, Shumaila et al.European journal of medicinal chemistry. 2012, Vol 47, pp 452-461, issn 0223-5234, 10 p.Article

Enaminones 12. An explanation of anticonvulsant activity and toxicity per Linus Pauling's clathrate hypothesisJACKSON, Patrice L; HANSON, Clive D; FARRELL, Alanna K et al.European journal of medicinal chemistry. 2012, Vol 51, pp 42-51, issn 0223-5234, 10 p.Article

Evaluation of synthetic acridones and 4-quinolinones as potent inhibitors of cathepsins L and VMARQUES, Emerson F; BUENO, Mauro A; DUARTE, Patricia D et al.European journal of medicinal chemistry. 2012, Vol 54, pp 10-21, issn 0223-5234, 12 p.Article

Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazolesCHIDANANDA, N; POOJARY, Boja; SUMANGALA, V et al.European journal of medicinal chemistry. 2012, Vol 51, pp 124-136, issn 0223-5234, 13 p.Article

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