BLOCKADE OF PHOTICALLY INDUCED EPILEPSY BY DOPAMINE AGONIST ERGOT ALKALOIDS.ANLEZARK G; MELDRUM B.1978; PSYCHOPHARMACOLOGY; GERM.; DA. 1978; VOL. 57; NO 1; PP. 57-62; BIBL. 31 REF.Article

GABA AGONISTS AND AUDIOGENIC SEIZURESANLEZARK G; COLLINS J; MELDRUM B et al.1978; NEUROSCI. LETTERS; NLD; DA. 1978; VOL. 7; NO 4; PP. 337-340; BIBL. 9 REF.Article

INHIBITION OF REFLEX EPILEPSY BY ( +OU- )-N-N-PROPYLNORAPOMORPHINE.ASHTON C; ANLEZARK G; MELDRUM B et al.1976; EUROP. J. PHARMACOL.; NETHERL.; DA. 1976; VOL. 39; NO 2; PP. 399-401; BIBL. 11 REF.Article

SEIZURE ACTIVITY IN PHOTOSENSITIVE BABOONS FOLLOWING ANTIDEPRESSANT DRUGS AND THE ROLE OF SEROTONINERGIC MECHANISMS.TRIMBLE M; ANLEZARK G; MELDRUM B et al.1977; PSYCHOPHARMACOLOGY; GERM.; DA. 1977; VOL. 51; NO 2; PP. 159-164; BIBL. 1 P.Article

ERGOT ALKALOIDS AS DOPAMINE AGONISTS: COMPARISON IN TWO RODENT MODELS.ANLEZARK G; PYCOCK C; MELDRUM B et al.1976; EUROP. J. PHARMACOL.; NETHERL.; DA. 1976; VOL. 37; NO 2; PP. 295-302; BIBL. 35 REF.Article

DRUGS MODIFYING DOPAMINERGIC ACTIVITY AND BEHAVIOUR, THE EEG AND EPILEPSY IN PAPIO PAPIO.MELDRUM B; ANLEZARK G; TRIMBLE M et al.1975; EUROP. J. PHARMACOL.; NETHERL.; DA. 1975; VOL. 32; NO 2; PP. 203-213; BIBL. 2 P.Article

THE ANTICONVULSANT ACTION OF THE (-)-AND (+)-ENANTIOMERS OF PROPRANOLOLANLEZARK G; HORTON R; MELDRUM B et al.1979; J. PHARM. PHARMACOL.; GBR; DA. 1979; VOL. 31; NO 7; PP. 482-483; BIBL. 17 REF.Article

PHOTICALLY INDUCED EPILEPSY IN PAPIO PAPIO AS A MODEL FOR DRUG STUDIES. = EPILEPSIE INDUITE PAR LA LUMIERE, CHEZ LE BABOUIN PAPIO-PAPIO, EN TANT QUE MODELE POUR DES ETUDES SUR DES "DROGUES"MELDRUM BS; ANLEZARK G; BALZAMO E et al.1975; ADV. NEUROL.; NETHERL.; DA. 1975; VOL. 10; PP. 119-128; BIBL. 45 REF.Article

ANTICONVULSANT ACTION OF ETHANOLAMINE-O-SULPHATE AND DI-N-PROPYLACETATE AND THE METABOLISM OF GAMMA -AMINOBUTYRIC ACID (GABA) IN MICE WITH AUDIOGENIC SEIZURESANLEZARK G; HORTON RW; MELDRUM BS et al.1976; BIOCHEM. PHARMACOL.; G.B.; DA. 1976; VOL. 25; NO 4; PP. 413-417; BIBL. 31 REF.Article

APORPHINES. XXXIV: (-)-2,10,11,-TRIHYDROXY-N-N-PROPYLNORAPORPHINE, A NOVEL DOPAMINERGIC APORPHINE ALKALOID WITH ANTICONVULSANT ACTIVITYNEUMEYER JL; LAW SJ; MELDRUM B et al.1981; J. MED. CHEM.; ISSN 0022-2623; USA; DA. 1981; VOL. 24; NO 7; PP. 898-899; BIBL. 14 REF.Article

Physical characterisation of the Escherichia coli B gene encoding nitroreductase and its over-expression in Escherichia coli K12MICHAEL, N. P; BREHM, J. K; ANLEZARK, G. M et al.FEMS microbiology letters. 1994, Vol 124, Num 2, pp 195-202, issn 0378-1097Article

The bioactivation of 5-(aziridin-1-yl)2,4-dinitrobenzamide (CB1954). II: A comparison of an Escherichia coli nitroreductase and walker DT diaphoraseKNOX, R. J; FRIEDLOS, F; SHERWOOD, R. F et al.Biochemical pharmacology. 1992, Vol 44, Num 12, pp 2297-2301, issn 0006-2952Article

Crystallization and preliminary crystallographic data for an FMN-dependent nitroreductase from Escherichia coli BSKELLY, J. V; COLLINS, P. J; KNOX, R. J et al.Journal of molecular biology. 1994, Vol 238, Num 5, pp 852-853, issn 0022-2836Article

Comparative assessment of dopamine agonist aporphines as anticonvulsants in two models of reflex epilepsyANLEZARK, G. M; BLACKWOOD, D. H. R; MELDRUM, B. S et al.Psychopharmacologia. 1983, Vol 81, Num 2, pp 135-139, issn 0033-3158Article

Synthesis of an aminopropyl analog of the experimental anticancer drug tallimustine, and activation of its 4-nitrobenzylcarbamoyl prodrug by nitroreductase and NADHLEE, M; SIMPSON, J. E; WOO, S et al.Bioorganic & medicinal chemistry letters (Print). 1997, Vol 7, Num 8, pp 1065-1070, issn 0960-894XArticle

The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954). I: Purification and properties of a nitroreductase enzyme from Escherichia coli : a potential enzyme for antibody-directed enzyme prodrug therapy (adept)ANLEZARK, G. M; MELTON, R. G; SHERWOOD, R. F et al.Biochemical pharmacology. 1992, Vol 44, Num 12, pp 2289-2295, issn 0006-2952Article

Virtual cofactors for an Escherichia coli nitroreductase enzyme : relevance to reductively activated prodrugs in antibody directed enzyme prodrug therapy (ADEPT)KNOX, R. J; FRIEDLOS, F; JARMAN, M et al.Biochemical pharmacology. 1995, Vol 49, Num 11, pp 1641-1647, issn 0006-2952Article

Repeated cycles of Clostridium-direeted enzyme prodrug therapy result in sustained antitumour effects in vivoTHEYS, J; PENNINGTON, O; WOUTERS, B. G et al.British journal of cancer. 2006, Vol 95, Num 9, pp 1212-1219, issn 0007-0920, 8 p.Article

Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductaseANLEZARK, G. M; MELTON, R. G; SHERWOOD, R. F et al.Biochemical pharmacology. 1995, Vol 50, Num 5, pp 609-618, issn 0006-2952Article