Molecular basis of antifolate resistance : Transporters in CancerASSARAF, Yehuda G.Cancer metastasis reviews. 2007, Vol 26, Num 1, pp 153-181, issn 0167-7659, 29 p.Article

MOLECULAR MECHANISMS OF ADAPTATION TO FOLATE DEFICIENCYIFERGAN, Ilan; ASSARAF, Yehuda G.Vitamins and hormones. 2008, Vol 79, pp 99-143, issn 0083-6729, 45 p.Article

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Probing ATP-dependent conformational changes in the multidrug resistance protein 1 (MRP1/ABCC1) in live tumor cells with a novel recombinant single-chain fv antibody targeted to the extracellular N-terminusBINYAMIN, Liat; ASSARAF, Yehuda G; REITER, Yoram et al.International journal of cancer. 2005, Vol 116, Num 5, pp 703-709, issn 0020-7136, 7 p.Article

Novel extracellular vesicles mediate an ABCG2-dependent anticancer drug sequestration and resistanceIFERGAN, Han; SCHEFFER, George L; ASSARAF, Yehuda G et al.Cancer research (Baltimore). 2005, Vol 65, Num 23, pp 10952-10958, issn 0008-5472, 7 p.Article

Beta-casein Nanoparticles as an Oral Delivery System for Chemotherapeutic Drugs: Impact of Drug Structure and Properties on Co-assemblySHAPIRA, Alina; ASSARAF, Yehuda G; EPSTEIN, Dikla et al.Pharmaceutical research. 2010, Vol 27, Num 10, pp 2175-2186, issn 0724-8741, 12 p.Article

Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemiaSTARK, Michal; WICHMAN, Chen; AVIVI, Irit et al.Blood. 2009, Vol 113, Num 18, pp 4362-4369, issn 0006-4971, 8 p.Article

Reduced folate carrier protein expression in osteosarcoma: Implications for the prediction of tumor chemosensitivityIFERGAN, Ilan; MELLER, Issac; ISSAKOV, Josefin et al.Cancer. 2003, Vol 98, Num 9, pp 1958-1966, issn 0008-543X, 9 p.Article

β-Casein nanoparticle-based oral drug delivery system for potential treatment of gastric carcinoma: Stability, target-activated release and cytotoxicitySHAPIRA, Alina; DAVIDSON, Irit; AVNI, Noa et al.European journal of pharmaceutics and biopharmaceutics. 2012, Vol 80, Num 2, pp 298-305, issn 0939-6411, 8 p.Article

Disruption of P-glycoprotein anticancer drug efflux activity by a small recombinant single-chain fv antibody fragment targeted to an extracellular epitopeHAUS-COHEN, Maya; ASSARAF, Yehuda G; BINYAMIN, Liat et al.International journal of cancer. 2004, Vol 109, Num 5, pp 750-758, issn 0020-7136, 9 p.Article

Optical and Magnetic Properties of Conjugate Structures of PbSe Quantum Dots and γ-Fe₂O₃ NanoparticlesETGAR, Lioz; LEITUS, Gregory; FRADKIN, Leonid et al.ChemPhysChem (Print). 2009, Vol 10, Num 13, pp 2235-2241, issn 1439-4235, 7 p.Article

Targeting an extracellular epitope of the human multidrug resistance protein 1 (MRP1) in malignant cells with a novel recombinant single chain Fv antibodyBINYAMIN, Liat; ASSARAF, Yehuda G; HAUS-COHEN, Maya et al.International journal of cancer. 2004, Vol 110, Num 6, pp 882-890, issn 0020-7136, 9 p.Article

C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cellsBRAM, Eran E; IFERGAN, Ilan; GRIMBERG, Michal et al.Biochemical pharmacology. 2007, Vol 74, Num 1, pp 41-53, issn 0006-2952, 13 p.Article

Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles : transcriptional silencing, inactivating mutations, and allele lossKAUFMAN, Yotam; IFERGAN, Ilan; ROTHEM, Lilah et al.Blood. 2006, Vol 107, Num 8, pp 3288-3294, issn 0006-4971, 7 p.Article

Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasisMAURITZ, Robert; PETERS, Godefridus J; PINEDO, Herbert M et al.Biochemical pharmacology. 2002, Vol 63, Num 2, pp 105-115, issn 0006-2952Article

High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicineBACHAS, Costa; SCHUURHUIS, Gerrit Jan; DE HAAS, Valerie et al.Blood. 2010, Vol 116, Num 15, pp 2752-2758, issn 0006-4971, 7 p.Article

ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolatesSHAFRAN, Assaf; IFERGAN, Ilan; BRAM, Eran et al.Cancer research (Baltimore). 2005, Vol 65, Num 18, pp 8414-8422, issn 0008-5472, 9 p.Article

Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1)HOOIJBERG, Jan Hendrik; JANSEN, Gerrit; ASSARAF, Yehuda G et al.Biochemical pharmacology. 2004, Vol 67, Num 8, pp 1541-1548, issn 0006-2952, 8 p.Article

Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancerDE WILT, Leonie H. A. M; JANSEN, Gerrit; ASSARAF, Yehuda G et al.Biochemical pharmacology. 2012, Vol 83, Num 2, pp 207-217, issn 0006-2952, 11 p.Article

Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug ResistanceGOTINK, Kristy J; BROXTERMAN, Henk J; GRIFFIOEN, Arjan W et al.Clinical cancer research (Print). 2011, Vol 17, Num 23, pp 7337-7346, issn 1078-0432, 10 p.Article

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasisHOOIJBERG, Jan Hendrik; PETERS, Godefridus J; ASSARAF, Yehuda G et al.Biochemical pharmacology. 2003, Vol 65, Num 5, pp 765-771, issn 0006-2952, 7 p.Article

Involvement of Breast Cancer Resistance Protein Expression on Rheumatoid Arthritis Synovial Tissue Macrophages in Resistance to Methotrexate and LeflunomideVAN DER HEIJDEN, Joost W; OERLEMANS, Ruud; JANSEN, Gerrit et al.Arthritis and rheumatism. 2009, Vol 60, Num 3, pp 669-677, issn 0004-3591, 9 p.Article

Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatinBERETTA, Giovanni Luca; BENEDETTI, Valentina; ZUNINO, Franco et al.Biochemical pharmacology. 2010, Vol 79, Num 8, pp 1108-1117, issn 0006-2952, 10 p.Article