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Feedback regulation of bile acid synthesis in primary human hepatocytes: Evidence that CDCA is the strongest inhibitorELLIS, Ewa; AXELSON, Magnus; ABRAHAMSSON, Anna et al.Hepatology (Baltimore, Md.). 2003, Vol 38, Num 4, pp 930-938, issn 0270-9139, 9 p.Article

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signalingRAZUVAEV, Anton; HENDERSON, Bimma; GIRNITA, Leonard et al.Journal of vascular surgery. 2007, Vol 46, Num 1, pp 108-115, issn 0741-5214, 8 p.Article

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathwayVASILCANU, Daiana; GIRNITA, Ada; GIRNITA, Leonard et al.Oncogene (Basingstoke). 2004, Vol 23, Num 47, pp 7854-7862, issn 0950-9232, 9 p.Article

Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: Clinical implicationsFENG, Xiaoying; ALEEM, Eiman; YINGBO LIN et al.International journal of oncology. 2012, Vol 40, Num 4, pp 1251-1258, issn 1019-6439, 8 p.Article

Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP : an in vitro and in vivo study in the 5T33MM mouse modelMENU, Eline; JERNBERG-WIKLUND, Helena; VANDERKERKEN, Kann et al.Blood. 2006, Vol 107, Num 2, pp 655-660, issn 0006-4971, 6 p.Article

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The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cellsGIRNITA, Ada; ALL-ERICSSON, Charlotta; ECONOMOU, Mario A et al.Clinical cancer research. 2006, Vol 12, Num 4, pp 1383-1391, issn 1078-0432, 9 p.Article

The HDAC Inhibitor LBH589 Enhances the Antimyeloma Effects of the IGF-1RTK Inhibitor PicropodophyllinLEMAIRE, Miguel; FRISTEDT, Charlotte; VAN CAMP, Ben et al.Clinical cancer research (Print). 2012, Vol 18, Num 8, pp 2230-2239, issn 1078-0432, 10 p.Article

Insulin-like growth factor-I is an important antiapoptotic factor for rat leydig cells during postnatal developmentCOLON, Eugenia; ZAMAN, Farasat; AXELSON, Magnus et al.Endocrinology (Philadelphia). 2007, Vol 148, Num 1, pp 128-139, issn 0013-7227, 12 p.Article

Hypoxia-lnducible factor-1α and hypoxia-inducible factor-2α are expressed in kaposi sarcoma and modulated by insulin-like growth factor-ICATRINA, Sergiu-Bogdan; BOTUSAN, Ileana Ruxandra; RANTANEN, Anja et al.Clinical cancer research. 2006, Vol 12, Num 15, pp 4506-4514, issn 1078-0432, 9 p.Article

IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G₂/M-phase accumulation and apoptosis in multiple myeloma cellsSTRÖMBERG, Thomas; EKMAN, Simon; VANDERKERKEN, Karin et al.Blood. 2006, Vol 107, Num 2, pp 669-678, issn 0006-4971, 10 p.Article