Designed Multiple Ligands: Basic Research vs Clinical OutcomesCOSTANTINO, L; BARLOCCO, D.Current medicinal chemistry. 2012, Vol 19, Num 20, pp 3353-3387, issn 0929-8673, 35 p.Article

Synthesis of a new series of 2,7-diazaspiro[3.5]nonan-1-ones and study of their cholinergic propertiesCIGNARELLA, G; VILLA, S; BARLOCCO, D et al.European journal of medicinal chemistry. 1994, Vol 29, Num 2, pp 115-120, issn 0223-5234Article

Synthesis and opioid receptor affinity of bivalent ligands derived from 3,8-diazabicyclo(3.2.1)octanesBARLOCCO, D; FADDA, P; FRATTA, W et al.Il Farmaco (Pavia). 1993, Vol 48, Num 3, pp 387-396, issn 0014-827XArticle

Synthesis and pharmacological evaluation of a new class of 2-oxo-8-azaspiro (4,5)decan-1-ones as analogues of the muscarinic agonist RS-86CIGNARELLA, G; VILLA, S; BARLOCCO, D et al.Il Farmaco (Pavia). 1993, Vol 48, Num 10, pp 1439-1445, issn 0014-827XArticle

Molecular mechanics of ¹H NMR conformational study of 3,8-diazabicyclo[3,2,1]octanes and related cis-2,6-dimethylpiperazines active on opioid receptorsTOMA, L; CIGNARELLA, G; BARLOCCO, D et al.Tetrahedron (Oxford. Print). 1992, Vol 48, Num 1, pp 159-166, issn 0040-4020Article

Spirocyclopropane carboxylic acids derived from 1-tetralone and 4-chromanone and their conversion to the corresponding pyridazinonesCIGNARELLA, G; BARLOCCO, D; ROSSI, G et al.Synthesis (Stuttgart). 1990, Num 2, pp 160-162, issn 0039-7881Article

Conformationally constrained congeners of 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinonesf active on the cardiovascular system : conformational studies by molecular mechanics calculations and ¹H NMR spectroscopyTOMA, L; CIGNARELLA, G; BARLOCCO, D et al.Journal of medicinal chemistry (Print). 1990, Vol 33, Num 6, pp 1591-1594, issn 0022-2623, 4 p.Article

Hydroxymethylation of 2-hydroxypropiophenones in aqueous medium: synthesis of 3-hydroxymethyl-3-methyl-4-chromanones and their conversion to 3-methyl-4-chromanone-3-acetic acidsBARLOCCO, D; CIGNARELLA, G; CURZU, M. M et al.Synthesis (Stuttgart). 1985, Num 9, pp 876-878, issn 0039-7881Article

Synthesis of 1,4-disubstituted-2-methylpiperazines and study of their analgesic propertiesBARLOCCO, D; BRUNELLO, N; BERNARDI, M et al.Il Farmaco (Pavia). 1995, Vol 50, Num 2, pp 119-124, issn 0014-827XArticle

Synthesis of a new series of N-substituted-3-[1-alkyl(aryl)-4-piperidyl]azetidin-2-ones as possible muscarinic agentsCIGNARELLA, G; VILLA, S; BARLOCCO, D et al.Journal of heterocyclic chemistry. 1993, Vol 30, Num 5, pp 1337-1340, issn 0022-152XArticle

Semicarbazide-sensitive amine oxidase: Current status and perspectivesMATYUS, P; DAJKA-HALASZ, B; FÖLDI, A et al.Current medicinal chemistry. 2004, Vol 11, Num 10, pp 1285-1298, issn 0929-8673, 14 p.Article

The opioid-receptor-like 1 (ORL-1) as a potential target for new analgesicsBARLOCCO, D; CIGNARELLA, G; GIARDINA, G. A. M et al.European journal of medicinal chemistry. 2000, Vol 35, Num 3, pp 275-282, issn 0223-5234Article

Thienocycloheptapyridazines as new muscarinic agentsBARLOCCO, D; CIGNARELLA, G; FANELLI, F et al.Drug design and discovery (Print). 1997, Vol 14, Num 4, pp 273-290, issn 1055-9612Article

Synthesis and pharmacological evaluation of 4,4a-dihydro-5H-[1]benzopyrano[4,3-c]pyridazin-3(2H)-ones bioisosters of antihypertensive and antithrombotic benzo[h]cinnolinonesDIGNARELLA, G; BARLOCCO, D; CURZU, M. M et al.European journal of medicinal chemistry. 1990, Vol 25, Num 9, pp 749-756, issn 0223-5234, 8 p.Article

Reinvestigation of the reaction of 3-hydroxy-2-methyl-1-aryl-1-propanones and related compounds with hydrazine and carboxylic acidsCIGNARELLA, G; BARLOCCO, D; CURZU, M. M et al.Synthesis (Stuttgart). 1989, Num 4, pp 320-321, issn 0039-7881, 2 p.Article

Characterization and pharmacological actions of tecostanine, an alkaloid of Tecoma stansCOSTANTINO, L; LINS, A. P; BARLOCCO, D et al.Pharmazie. 2003, Vol 58, Num 2, pp 140-142, issn 0031-7144, 3 p.Article

Mono- and disubstituted-3,8-diazabicyclo[3.2.1]octane derivatives as analgesics structurally related to epibatidine : Synthesis, activity, and modelingBARLOCCO, D; CIGNARELLA, G; COLOMBO, D et al.Journal of medicinal chemistry (Print). 1998, Vol 41, Num 5, pp 674-681, issn 0022-2623Article

Synthesis and pharmacological evaluation of thienocinnolin-3-(2H)-ones, bioisosters of antihypertensive and antithrombotic benzo(h)cinnolinonesPINNA, G. A; CURZU, M. M; CIGNARELLA, G et al.European journal of medicinal chemistry. 1994, Vol 29, Num 6, pp 447-454, issn 0223-5234Article

Synthesis of a new series of 2,8-disubstituted-2,8-diazaspiro[4,5]decan-1-ones as potential muscarinic agonistsCIGNARELLA, G; VILLA, S; CATTABENI, F et al.European journal of medicinal chemistry. 1994, Vol 29, Num 12, pp 955-961, issn 0223-5234Article

Hydroxymethylation of propiophenones in aqueous medium: a new route to 1-aryl-2-methyl-2-propen-1-onesCURZU, M. M; PINNA, G. A; BARLOCCO, D et al.Synthesis (Stuttgart). 1984, Num 4, pp 339-342, issn 0039-7881Article

Thymidylate synthase structure, function and implication in drug discoveryCOSTI, M. P; FERRARI, S; VENTURELLI, A et al.Current medicinal chemistry. 2005, Vol 12, Num 19, pp 2241-2258, issn 0929-8673, 18 p.Article

Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitorsCOSTANTINO, L; RASTELLI, G; GAMBERINI, M. C et al.Journal of medicinal chemistry (Print). 1999, Vol 42, Num 11, pp 1894-1900, issn 0022-2623Article

Phthalein derivatives as a new tool for selectivity in thymidylate synthase inhibitionCOSTI, P. M; RINALDI, M; MARANGIU, E. M et al.Journal of medicinal chemistry (Print). 1999, Vol 42, Num 12, pp 2112-2124, issn 0022-2623Article

Antiamnesic activity of the nicotinic agonist DBO-83 in miceGHELARDINI, C; GALEOTTI, N; GIULIANI, F et al.Drug development research. 1998, Vol 45, Num 2, pp 45-51, issn 0272-4391Article

2-(substituted)amino-2,8-diazaspiro[4,5] decan-1,3-diones as potential muscarinic agonists : Synthesis, modeling and binding studiesBARLOCCO, D; FANELLI, F; CIGNARELLA, G et al.Drug design and discovery (Print). 1996, Vol 14, Num 2, pp 129-143, issn 1055-9612Article