Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugsSTOKVIS, Ellen; ROSING, Hilde; BEIJNEN, Jos H et al.Mass spectrometry reviews (Print). 2005, Vol 24, Num 6, pp 887-917, issn 0277-7037, 31 p.Article

High-performance liquid chromatography analysis of a novel small-molecule, anti-cancer drug, Palomid 529, in human and mouse plasma and in mouse tissue homogenatesFAN LIN; SHERRIS, David; BEIJNEN, Jos H et al.Journal of chromatography. B. 2011, Vol 879, Num 32, pp 3823-3831, issn 1570-0232, 9 p.Article

The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteersGOEY, Andrew K. L; MEIJERMAN, Irma; BEIJNEN, Jos H et al.European journal of clinical pharmacology. 2013, Vol 69, Num 11, pp 1883-1890, issn 0031-6970, 8 p.Article

Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometryVAN DEN BROEK, Irene; SPARIDANS, Rolf W; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2010, Vol 878, Num 5-6, pp 590-602, issn 1570-0232, 13 p.Article

Validation of a quantitative assay for human neutrophil peptide-1, -2, and -3 in human plasma and serum by liquid chromatography coupled to tandem mass spectrometryVAN DEN BROEK, Irene; SPARIDANS, Rolf W; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2010, Vol 878, Num 15-16, pp 1085-1092, issn 1570-0232, 8 p.Article

Altered cyclophosphamide and thiotepa pharmacokinetics in a patient with moderate renal insufficiencyEKHART, Corine; MARTIJN KERST, J; RODENHUIS, Sjoerd et al.Cancer chemotherapy and pharmacology. 2009, Vol 63, Num 2, pp 375-379, issn 0344-5704, 5 p.Article

Protein versus DNA as a marker for peripheral blood mononuclear cell countingJANSEN, Robert S; ROSING, Hilde; SCHELLENS, Jan H. M et al.Analytical & bioanalytical chemistry (Print). 2009, Vol 395, Num 3, pp 863-867, issn 1618-2642, 5 p.Article

Development of pharmaceutical heroin preparations for medical co-prescription to opioid dependent patientsKLOUS, Marjolein G; VAN DEN BRINK, Wim; VAN REE, Jan M et al.Drug and alcohol dependence. 2005, Vol 80, Num 3, pp 283-295, issn 0376-8716, 13 p.Article

Liquid chromatographic assay for the antiviral nucleotide analogue tenofovir in plasma using derivatization with chloroacetaldehydeSPARIDANS, Rolf W; CROMMENTUYN, Kristel M. L; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2003, Vol 791, Num 1-2, pp 227-233, issn 1570-0232, 7 p.Article

The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in micePRESS, Rogier R; BUCKLE, Tessa; BEIJNEN, Jos H et al.Cancer chemotherapy and pharmacology. 2006, Vol 57, Num 6, pp 819-825, issn 0344-5704, 7 p.Article

Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the Blood―Brain Barrier without restriction by ABCB1 and ABCG2FAN LIN; BUIL, Levi; SHERRIS, David et al.International journal of cancer (Print). 2013, Vol 133, Num 5, pp 1222-1233, issn 0020-7136, 12 p.Article

Characterization and identification of suspected counterfeit miltefosine capsulesDORLO, Thomas P. C; EGGELTE, Teunis A; DE VRIES, Peter J et al.Analyst (London. 1877. Print). 2012, Vol 137, Num 5, pp 1265-1274, issn 0003-2654, 10 p.Article

A less sensitive detector does not necessarily result in a less sensitive method: fast quantification of 13 antiretroviral analytes in plasma with liquid chromatography coupled with tandem mass spectrometryTER HEINE, Rob; ROSING, Hilde; BEIJNEN, Jos H et al.Clinical chemistry and laboratory medicine. 2010, Vol 48, Num 8, pp 1153-1155, issn 1434-6621, 3 p.Article

Severe encephalopathy and polyneuropathy induced by dichloroacetateBRANDSMA, Dieta; DORLO, Thomas P. C; HAANEN, John H et al.Journal of neurology. 2010, Vol 257, Num 12, pp 2099-2100, issn 0340-5354, 2 p.Article

Simultaneous determination of AZD1152 (prodrug) and AZD1152-hydroxyquinazoline pyrazol anilide by reversed phase liquid chromatographyPLUIM, Dick; BEIJNEN, Jos H; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2009, Vol 877, Num 29, pp 3549-3555, issn 1570-0232, 7 p.Article

Enzymatic digestion as a tool for the LC-MS/MS quantification of large peptides in biological matrices : Measurement of chymotryptic fragments from the HIV-1 fusion inhibitor enfuvirtide and its metabolite M-20 in human plasmaVAN DEN BROEK, Irene; SPARIDANS, Rolf W; SCHELLENS, Jan H. M et al.Journal of chromatography. B. 2007, Vol 854, Num 1-2, pp 245-259, issn 1570-0232, 15 p.Article

The effect of hydroxyurea on P-glycoprotein/BCRP-mediated transport and CYP3A metabolism of imatinib mesylateOOSTENDORP, Roos L; MARCHETTI, Serena; BEIJNEN, Jos H et al.Cancer chemotherapy and pharmacology. 2007, Vol 59, Num 6, pp 855-860, issn 0344-5704, 6 p.Article

The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in miceKEMPER, E. Marleen; CLEYPOOL, Cindy; BOOGERD, Willem et al.Cancer chemotherapy and pharmacology. 2004, Vol 53, Num 2, pp 173-178, issn 0344-5704, 6 p.Article

High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasmaSCHOEMAKER, Nadja E; ROSING, Hilde; JANSEN, Sindy et al.Therapeutic drug monitoring. 2003, Vol 25, Num 1, pp 120-124, issn 0163-4356, 5 p.Article

Simple and rapid method for the simultaneous determination of the non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine in human plasma using liquid chromatographyKAPPELHOFF, Bregt S; ROSING, Hilde; HUITEMA, Alwin D. R et al.Journal of chromatography. B. 2003, Vol 792, Num 2, pp 353-362, issn 1570-0232, 10 p.Article

Population pharmacokinetics of ifosfamide and its dechloroethylated and hydroxylated metabolites in children with malignant disease A sparse sampling approachKERBUSCH, Thomas; DE KRAKER, Jan; MATHOT, Ron A. A et al.Clinical pharmacokinetics. 2001, Vol 40, Num 8, pp 615-625, issn 0312-5963Article

Oral delivery of taxanesMALINGRE, Mirte M; BEIJNEN, Jos H; SCHELLENS, Jan H. M et al.Investigational new drugs. 2001, Vol 19, Num 2, pp 155-162, issn 0167-6997Article

Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for ImprovementSTUURMAN, Frederik E; NUIJEN, Bastiaan; BEIJNEN, Jos H et al.Clinical pharmacokinetics. 2013, Vol 52, Num 6, pp 399-414, issn 0312-5963, 16 p.Article

Deoxyuridine analog nucleotides in deoxycytidine analog treatment: secondary active metabolites?JANSEN, Robert S; ROSING, Hilde; SCHELLENS, Jan Hm et al.Fundamental & clinical pharmacology. 2011, Vol 25, Num 2, pp 172-185, issn 0767-3981, 14 p.Article

Clinical Pharmacokinetics of Therapeutic Monoclonal AntibodiesKEIZER, Ron J; HUITEMA, Alwin D. R; SCHELLENS, Jan H. M et al.Clinical pharmacokinetics. 2010, Vol 49, Num 8, pp 493-507, issn 0312-5963, 15 p.Article