Interindividual variations in drug disposition: clinical implications and methods of investigationBREIMER, D. D.Clinical pharmacokinetics. 1983, Vol 8, Num 5, pp 371-377, issn 0312-5963Article

An integrated pharmacokinetic and pharmacodynamic approach to controlled drug deliveryBREIMER, D. D.Journal of drug targeting. 1996, Vol 3, Num 6, pp 411-415, issn 1061-186XArticle

Future challenges for drug deliveryBREIMER, D. D.Journal of controlled release. 1999, Vol 62, Num 1-2, pp 3-6, issn 0168-3659Conference Paper

Future challenges for drug delivery researchBREIMER, D. D.Advanced drug delivery reviews. 1998, Vol 33, Num 3, pp 265-268, issn 0169-409XArticle

Relevance of the application of pharmacokinetic-pharmacodynamic modelling concepts in drug development : The 'wooden shoe' paradigmBREIMER, D. D; DANHOF, M.Clinical pharmacokinetics. 1997, Vol 32, Num 4, pp 259-267, issn 0312-5963Article

The CED-le DEC : Common European doctorate, or doctorate Europeen commune or dissertations on the InternetBREIMER, L. H; BREIMER, D. D.Scientometrics (Print). 1996, Vol 35, Num 3, pp 347-353, issn 0138-9130Article

The blood-brain barrier : clinical implications for drug delivery to the brainDE BOER, A. G; BREIMER, D. D.Journal of the Royal College of Physicians of London. 1994, Vol 28, Num 6, pp 502-506, issn 0035-8819Article

Microsomal and cytosolic epoxide hydrolase in Drosophila melanogasterJANSEN, M; BAARS, A. J; BREIMER, D. D et al.Biochemical pharmacology. 1986, Vol 35, Num 13, pp 2229-2232, issn 0006-2952Article

Pharmacokinetic-pharmacodynamic modeling of CNS drug effects: an overviewDINGEMANSE, J; DANHOF, M; BREIMER, D. D et al.Pharmacology & therapeutics (Oxford). 1988, Vol 38, Num 1, pp 1-52, issn 0163-7258Article

Stereoselective pharmacokinetics of oral and intravenous nitrendipine in healthy male subjectsSOONS, P. A; BREIMER, D. D.British journal of clinical pharmacology. 1991, Vol 32, Num 1, pp 11-16, issn 0306-5251, 6 p.Article

Microsomal and cytosolic epoxide hydrolase in Drosophila melanogasterJANSEN, M; BAARS, A. J; BREIMER, D. D et al.Biochemical pharmacology. 1986, Vol 35, Num 13, pp 2229-2232, issn 0006-2952Article

Rectal, oral and I. A. administration of etomidate to rats : significant avoidance of hepatic first-pass elimination following rectal administrationDE BOER, A. G; BREIMER, D. D.Archives internationales de pharmacodynamie et de thérapie. 1984, Vol 270, Num 2, pp 180-191, issn 0003-9780Article

Effects of acute febrile infectious diseases on the oral pharmacokinetics and effects of nitrendipine enantiomers and of bisoprololSOONS, P. A; GRIB, C; BREIMER, D. D et al.Clinical pharmacokinetics. 1992, Vol 23, Num 3, pp 238-248, issn 0312-5963Article

Effects of single-dose and short-term oral nifedipine on indocyanine green clearance as assessed by spectrophotometry and high performance liquid chromatographySOONS, P. A; KROON, J. M; BREIMER, D. D et al.Journal of clinical pharmacology. 1990, Vol 30, Num 8, pp 693-698, issn 0091-2700, 6 p.Article

Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjectsSCHELLENS, J. H. M; SOONS, P. A; BREIMER, D. D et al.Biochemical pharmacology. 1988, Vol 37, Num 13, pp 2507-2510, issn 0006-2952Article

Pharmacokinetics of rectal drug administration. I, General considerations and clinical applications of centrally acting drugsVAN HOOGDALEM, E. J; DE BOER, A. G; BREIMER, D. D et al.Clinical pharmacokinetics. 1991, Vol 21, Num 1, pp 11-26, issn 0312-5963, 16 p.Article

The transference of results between blood-brain barrier cell culture systemsDE BOER, A. G; GAILLARD, P. J; BREIMER, D. D et al.European journal of pharmaceutical sciences. 1999, Vol 8, Num 1, pp 1-4, issn 0928-0987Article

Complete rectal absorption of theophylline in rats without absorption enhancerVAN HOOGDALEM, E. J; DE BOER, A. G; BREIMER, D. D et al.Journal of pharmaceutical sciences. 1986, Vol 75, Num 9, pp 917-918, issn 0022-3549Article

Nifedipine: variability in its kinetics and metabolism in manBREIMER, D. D; SCHELLENS, J. H. M; SOONS, P. A et al.Pharmacology & therapeutics (Oxford). 1989, Vol 44, Num 3, pp 445-3454, issn 0163-7258Article

Hepatic first-pass effect and controlled drug delivery following rectal administrationDE BOER, A. G; BREIMER, D. D.Advanced drug delivery reviews. 1997, Vol 28, Num 2, pp 229-237, issn 0169-409XArticle

Intestinal drug absorption enhancement: an overviewVAN HOOGDALEM, E. J; DE BOER, A. G; BREIMER, D. D et al.Pharmacology & therapeutics (Oxford). 1989, Vol 44, Num 3, pp 407-443, issn 0163-7258Article

Disposition of hexobarbital: 15 years of an intriguing model substrateVAN DER GRAAFF, M; VERMEULEN, N. P. E; BREIMER, D. D et al.Drug metabolism reviews (Softcover ed.). 1988, Vol 19, Num 2, pp 109-164, issn 0360-2532Article

Route- and dose-dependent pharmacokinetics of hexobartitone in the rat: a re-evaluation of the use of sleeping times in metabolic studiesVAN DER GRAAFF, M; VERMEULEN, N. P. E; BREIMER, D. D et al.Journal of pharmacy and pharmacology. 1985, Vol 37, Num 8, pp 550-554, issn 0022-3573Article

Stereoselective pharmacokinetics of oral nitrendipine in elderly hypertensive patients with normal and impaired renal functionSOONS, P. A; ANKERMANN, T; BREIMER, D. D et al.European journal of clinical pharmacology. 1992, Vol 42, Num 4, pp 423-427, issn 0031-6970Article

Disposition of hexobarbitone in healthy man: kinetics of parent drug and metabolites following oral administrationVERMEULEN, N. P. E; RIETVELD, C. T; BREIMER, D. D et al.British journal of clinical pharmacology. 1983, Vol 15, Num 4, pp 459-464, issn 0306-5251Article