Novel series of TSAO-T derivatives. Synthesis and anti-HIV-1 activity of 4-, 5-, and 6-substituted pyrimidine analoguesSAN-FELIX, A; VELAZQUEZ, S; PEREZ-PEREZ, M. J et al.Journal of medicinal chemistry (Print). 1994, Vol 37, Num 4, pp 453-460, issn 0022-2623Article

1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl]-3'-spiro-5-(4-amino-1,2-oxathiole 2,2-dioxide) (TSAO) analogues : synthesis and anti-HIV-1 activityALVAREZ, R; VELAZQUEZ, S; SAN-FELIX, A et al.Journal of medicinal chemistry (Print). 1994, Vol 37, Num 24, pp 4185-4194, issn 0022-2623Article

Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptaseVELAZQUEZ, S; ALVAREZ, R; SAN-FELIX, A et al.Journal of medicinal chemistry (Print). 1995, Vol 38, Num 10, pp 1641-1649, issn 0022-2623Article

Reactions of 1-glucosyl-5-nitro-1,2,4-triazole with nucleophilesCAMARASA, M. J; DE LAS HERAS, F. G.Journal of heterocyclic chemistry. 1983, Vol 20, Num 5, pp 1307-1309, issn 0022-152XArticle

TSAO derivatives, inhibitors of HIV-1 reverse transcriptase dimerization : Recent progress : HIV-1 reverse transcriptase inhibitors: Drug resistance and drug developmentCAMARASA, M. J; VELAZQUEZ, S; SAN-FELIX, A et al.Current pharmaceutical design. 2006, Vol 12, Num 15, pp 1895-1907, issn 1381-6128, 13 p.Article

A new procedure for the synthesis of glycosyl isothiocyanatesCAMARASA, M. J; FERNANDEZ-RESA, P; GARCIA-LOPEZ, M. T et al.Synthesis (Stuttgart). 1984, Num 6, pp 509-510, issn 0039-7881Article

Alkylidene carbenes as intermediates in the synthesis of highly functionalized branched-chain sugars and nucleosidesPEREZ-PEREZ, M.-J; CAMARASA, M.-J.Tetrahedron (Oxford. Print). 1994, Vol 50, Num 24, issn 0040-4020, IX, 7269-7282 [15 p.]Article

Synthesis and anti-HIV-1 activity of [1-[2',5'Bis-O-(tert-butyldimethylsilyl)-β-L-ribofuranosyl]thymine]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (L-TSAO-T), the L-enantiomer of the highly specific HIV-1 reverse transcriptase inhibitor TSAO-TINGATE, S. T; CAMARASA, M.-J; DE CLERCQ, E et al.Antiviral chemistry & chemotherapy. 1995, Vol 6, Num 6, pp 365-370, issn 0956-3202Article

N-(glucopyranosid-3-yl)-D-alanyl-L-alanyl-D-isoglutamine and related tripeptide analogues of muramyl dipeptideCALVO-MATEO, A; CAMARASA, M.-J; DE LAS HERAS, F. G et al.Tetrahedron (Oxford. Print). 1986, Vol 42, Num 14, pp 4049-4056, issn 0040-4020Article

TSAO-T analogues bearing amino acids at position N-3 of thymine: synthesis and anti-human immunodeficiency virus activityCHAMORRO, C; DE CLERCQ, E; BALZARINI, J et al.Antiviral chemistry & chemotherapy. 2000, Vol 11, Num 1, pp 61-69, issn 0956-3202Article

Aldol reaction of nucleoside 5'-carboxaldehydes with acetone. Synthesis of 5'-C-chain extended thymidine derivativesCAMARASA, M.-J; DE LAS HEARS, F. G; PEREZ-PEREZ, M. J et al.Nucleosides & nucleotides. 1990, Vol 9, Num 4, pp 533-546, issn 0732-8311, 14 p.Article

Synthesis of asymmetrically substituted aminohalogenobenzimidazolesCAMARASA, M.-J; COE, P. L; JONES, A. S et al.Journal of the Chemical Society. Perkin transactions. I. 1987, Num 11, pp 2317-2320, issn 0300-922XArticle

Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virusBALZARINI, J; KARLSSON, A; PEREZ-PEREZ, M.-J et al.Virology (New York, NY). 1993, Vol 196, Num 2, pp 576-585, issn 0042-6822Article

3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors : synthesis and antiviral activity of [2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-xylo- and -ribofuranose]-3'-spiro-5-[4-amino-1,2-oxathiole 2,2-dioxide] (TSAO) pyrimidine nucleosidesCAMARASA, M.-J; PEREZ-PEREZ, M.-J; BALZARINI, J et al.Journal of medicinal chemistry (Print). 1992, Vol 35, Num 15, pp 2721-2727, issn 0022-2623Article

3'-C-cyano-3'-deoxythymidineCALVO-MATEO, A; CAMARASA, M.-J; DIAZ-ORTIZ, A et al.Tetrahedron letters. 1988, Vol 29, Num 8, pp 941-944, issn 0040-4039Article

Synthesis of 3'-C-cyano-3'-deoxy-pentofuranosylthymine nucleosidesCALVO-MATEO, A; CAMARASA, M.-J; DIAZ-ORTIZ, A et al.Tetrahedron (Oxford. Print). 1988, Vol 44, Num 15, pp 4895-4903, issn 0040-4020Article

Aldol reaction of reducing sugars: convenient stereoselective synthesis of ribofuranosylacetone and chiral dienonesCALVO-MATEO, A; CAMARASA, M.-J; DIAZ-ORTIZ, A et al.Journal of the Chemical Society. Perkin transactions. I. 1988, Num 10, pp 2861-2863, issn 0300-922XArticle

An approach towards the synthesis of potential metal-chelating TSAO-T derivatives as bidentate inhibitors of human immunodeficiency virus type 1 reverse transcriptaseCHAMORRO, C; CAMARASA, M.-J; PEREZ-PEREZ, M.-J et al.Antiviral chemistry & chemotherapy. 1998, Vol 9, Num 5, pp 413-423, issn 0956-3202Article

Metabolism and pharmacokinetics of the anti-HIV-1-specific inhibitor [1-[2',5'-Bis-O-(tert-butyldimethylsilyl)β-D-ribofuranosyl]-3-N-methyl-thymine]-3'-spiro-5″-(4″-amino-1″,2″-oxathiole-2″,2″-dioxide)BALZARINI, J; NAESENS, L; BOHMAN, C et al.Biochemical pharmacology. 1993, Vol 46, Num 1, pp 69-77, issn 0006-2952Article

Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylaseESTEBAN-GAMBOA, A; BALZARINI, J; ESNOUF, R et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 5, pp 971-983, issn 0022-2623Article

Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapyBALZARINI, J; KARLSSON, A; PEREZ-PEREZ, M.-J et al.Journal of virology. 1993, Vol 67, Num 9, pp 5353-5359, issn 0022-538XArticle

Synthesis and antiviral activity of 3'-C-cyano-3'-deoxynucleosidesCAMARASA, M.-J; DIAZ-ORTIZ, A; CALVO-MATEO, A et al.Journal of medicinal chemistry (Print). 1989, Vol 32, Num 8, pp 1732-1738, issn 0022-2623, 7 p.Article

Synthesis and anti-human immunodeficiency virus type 1 activity of novel 3'-spiro nucleoside analogues of TSAO-TALVAREZ, R; JIMENO, M.-L; PEREZ-PEREZ, M.-J et al.Antiviral chemistry & chemotherapy. 1997, Vol 8, Num 6, pp 507-517, issn 0956-3202Article

[2',5'-bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4-amino-1,2-oxathiole-2,2-dioxide) (TSAO) derivatives of purine and pyrimidine nucleosides as potent and selective inhibitors of human immunodeficiency virus type 1BALZARINI, J; PEREZ-PEREZ, M.-J; SAN-FELIX, A et al.Antimicrobial agents and chemotherapy. 1992, Vol 36, Num 5, pp 1073-1080, issn 0066-4804Article

Stereospecific synthesis of branched-chain sugars by a novel aldol-type cyclocondensationPEREZ-PEREZ, M.-J; CAMARASA, M.-J; DIAZ-ORTIZ, A et al.Carbohydrate research. 1991, Vol 216, pp 399-411, issn 0008-6215Article