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Identification of (3R)-7-hydroxy-N-((1S)-1-{[(3R, 4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidiny l]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide as a novel potent and selective opioid K receptor antagonistTHOMAS, James B; ATKINSON, Robert N; CANTRELL, Buddy E et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 14, pp 3127-3137, issn 0022-2623, 11 p.Article

Identification of the first trans-(3R, 4R)-dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid k receptor antagonist activityTHOMAS, James B; ATKINSON, Robert N; ZIMMERMAN, Dennis M et al.Journal of medicinal chemistry (Print). 2001, Vol 44, Num 17, pp 2687-2690, issn 0022-2623Article

Importance of phenolic address groups in opioid kappa receptor selective antagonistsTHOMAS, James B; FIX, Scott E; ROTHMAN, Richard B et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 4, pp 1070-1073, issn 0022-2623, 4 p.Article

Discovery of an opioid κK receptor selective pure antagonist from a library of N-substituted 4β-methyl-5-(3-hydroxyphenyl)morphansTHOMAS, James B; ATKINSON, Robert N; DERSCH, Christina M et al.Journal of medicinal chemistry (Print). 2002, Vol 45, Num 16, pp 3524-3530, issn 0022-2623Article