Murine models of intestinal cancer : Recent advancesSHAW, Paul; CLARKE, Alan R.DNA repair. 2007, Vol 6, Num 10, pp 1403-1412, issn 1568-7864, 10 p.Article

Wnt-cadherin connections in normal and neoplastic mammary epitheliumMENIEL, Valerie; CLARKE, Alan R.Journal of mammary gland biology and neoplasia. 2003, Vol 8, Num 4, pp 435-447, issn 1083-3021, 13 p.Article

P53 null mice : damaging the hypothesis?SANSOM, Owen J; CLARKE, Alan R.Mutation research. 2000, Vol 452, Num 2, pp 149-162, issn 0027-5107Article

Gene manipulation through the use of small interfering RNA (siRNA) : From in vitro to in vivo applicationsLEKHA DINESH KUMAR; CLARKE, Alan R.Advanced drug delivery reviews. 2007, Vol 59, Num 2-3, pp 87-100, issn 0169-409X, 14 p.Article

p53 mediates a default programme of mammary gland involution in the absence of STAT3MATTHEWS, James R; CLARKE, Alan R.Oncogene (Basingstoke). 2005, Vol 24, Num 19, pp 3083-3090, issn 0950-9232, 8 p.Article

The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient miceSANSOM, Owen J; CLARKE, Alan R.Oncogene (Basingstoke). 2002, Vol 21, Num 38, pp 5934-5939, issn 0950-9232, 6 p.Article

Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with CarboplatinHAY, Trevor; MATTHEW, James R; CLARKE, Alan R et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 9, pp 3850-3855, issn 0008-5472, 6 p.Article

A role for mismatch repair in control of DNA ploidy following DNA damageSTRATHDEE, Gordon; SANSOM, Owen J; SIM, Alyson et al.Oncogene (Basingstoke). 2001, Vol 20, Num 15, pp 1923-1927, issn 0950-9232Article

Crypt stem cells as the cells-of-origin of intestinal cancerBARKER, Nick; RIDGWAY, Rachel A; VAN ES, Johan H et al.Nature (London). 2009, Vol 457, Num 7229, pp 608-611, issn 0028-0836, 4 p.Article

MBD4 deficiency does not increase mutation or accelerate tumorigenesis in mice lacking MMRSANSOM, Owen J; BISHOP, Stefan M; BIRD, Adrian et al.Oncogene (Basingstoke). 2004, Vol 23, Num 33, pp 5693-5696, issn 0950-9232, 4 p.Article

PPARδ status and Apc-mediated tumourigenesis in the mouse intestineREED, Karen R; SANSOM, Owen J; HAYES, Anthony J et al.Oncogene (Basingstoke). 2004, Vol 23, Num 55, pp 8992-8996, issn 0950-9232, 5 p.Article

Single cell tracking reveals that Msh2 is a key component of an early-acting DNA damage-activated G2 checkpointMARQUEZ, Nuria; CHAPPELL, Sally C; SANSOM, Owen J et al.Oncogene (Basingstoke). 2003, Vol 22, Num 48, pp 7642-7648, issn 0950-9232, 7 p.Article

K-ras and Wnt Signaling Synergize to Accelerate Prostate Tumorigenesis in the MousePEARSON, Helen B; PHESSE, Toby J; CLARKE, Alan R et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 1, pp 94-101, issn 0008-5472, 8 p.Article

Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc SignalingASHTON, Gabrielle H; MORON, Jennifer P; NEUFELD, Kristi et al.Developmental cell. 2010, Vol 19, Num 2, pp 259-269, issn 1534-5807, 11 p.Article

Lkb1 Deficiency Causes Prostate Neoplasia in the MousePEARSON, Helen B; MCCARTHY, Afshan; COFFINS, Christopher M. P et al.Cancer research (Baltimore). 2008, Vol 68, Num 7, pp 2223-2232, issn 0008-5472, 10 p.Article

Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutationMARSH, Victoria; WINTON, Douglas J; WILLIAMS, Geraint T et al.Nature genetics. 2008, Vol 40, Num 12, pp 1436-1444, issn 1061-4036, 9 p.Article

Aspirin activates the NF-κB signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancerSTARK, Lesley A; REID, Kirsten; SANSOM, Owen J et al.Carcinogenesis (New York. Print). 2007, Vol 28, Num 5, pp 968-976, issn 0143-3334, 9 p.Article

Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapyHAY, Trevor; JENKINS, Helen; SANSOM, Owen J et al.Cancer research (Baltimore). 2005, Vol 65, Num 22, pp 10145-10148, issn 0008-5472, 4 p.Article

Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient backgroundTOFT, Neil J; CURTIS, Lucy J; SANSOM, Owen J et al.Oncogene (Basingstoke). 2002, Vol 21, Num 41, pp 6299-6306, issn 0950-9232Article

Genetic interactions between the Wilms' Tumor 1 gene and the p53 geneMENKE, Aswin L; CLARKE, Alan R; LEITCH, Andrea et al.Cancer research (Baltimore). 2002, Vol 62, Num 22, pp 6615-6620, issn 0008-5472, 6 p.Article

Intestinal renin-angiotensin system is stimulated after deletion of Lkb1SHORNING, Boris Y; JARDE, Thierry; MCCARTHY, Afshan et al.Gut. 2012, Vol 61, Num 2, pp 202-213, issn 0017-5749, 12 p.Article

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cellsSMARTT, Helena J. M; GREENHOUGH, Alexander; CLARKE, Alan R et al.Gut. 2012, Vol 61, Num 9, pp 1306-1314, issn 0017-5749, 9 p.Article

Myc deletion rescues Apc deficiency in the small intestineSANSOM, Owen J; MENIEL, Valerie S; MUNCAN, Vanesa et al.Nature (London). 2007, Vol 446, Num 7136, pp 676-679, issn 0028-0836, 4 p.Article

Apoptosis and mutation in the murine small intestine: loss of M1h1- and Pms2-dependent apoptosis leads to increased mutation in vivoSANSOM, Owen J; BISHOP, Stefan M; COURT, Helen et al.DNA repair. 2003, Vol 2, Num 9, pp 1029-1039, issn 1568-7864, 11 p.Article

Deficiency of Mbd2 suppresses intestinal tumorigenesisSANSOM, Owen J; BERGER, Jennifer; BISHOP, Stefan M et al.Nature genetics. 2003, Vol 34, Num 2, pp 145-147, issn 1061-4036, 3 p.Article