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Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 miceBUTTERWORTH, B. E; TEMPLIN, M. V; CONSTAN, A. A et al.Environmental and molecular mutagenesis (Print). 1998, Vol 31, Num 3, pp 248-256, issn 0893-6692Article

Incorporating Monte Carlo simulation into physiologically based pharmacokinetic models using advanced continuous simulation language (ACSL) : A computational methodTHOMAS, R. S; LYTLE, W. E; KEEFE, T. J et al.Fundamental and applied toxicology (Print). 1996, Vol 31, Num 1, pp 19-28, issn 0272-0590Article

The use of physiologically-based pharmacokinetic/pharmacodynamic dosimetry models for chemical mixturesYANG, R. S. H; EL-MASRI, H. A; THOMAS, R. S et al.Toxicology letters. 1995, Vol 82-83, pp 497-504, issn 0378-4274Conference Paper

1995 STP young investigator award recipient : Increased rate of apoptosis correlates with hepatocellular proliferation in Fischer-344 rats following long-term exposure to a mixture of groundwater contaminantsCONSTAN, A. A; BENJAMIN, S. A; TESSARI, J. D et al.Toxicologic pathology. 1996, Vol 24, Num 3, pp 315-322, issn 0192-6233Article

A unique pattern of hepatocyte proliferation in F344 rats following long-term exposures to low levels of a chemical mixture of groundwater contaminantsCONSTAN, A. A; YANG, R. S. H; BAKER, D. C et al.Carcinogenesis (New York. Print). 1995, Vol 16, Num 2, pp 303-310, issn 0143-3334Article

Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male miceCONSTAN, A. A; SPRANKLE, C. S; PETERS, J. M et al.Toxicology and applied pharmacology. 1999, Vol 160, Num 2, pp 120-126, issn 0041-008XArticle

Patterns of chloroform-induced regenerative cell proliferation in BDF1 mice correlate with organ specificity and dose-response of tumor formationTEMPLIN, M. V; CONSTAN, A. A; WOLF, D. C et al.Carcinogenesis (New York. Print). 1998, Vol 19, Num 1, pp 187-193, issn 0143-3334Article

Physiologically based pharmacokinetic/pharmacodynamic modeling of the toxicologic interaction between carbon tetrachloride and KeponeEL-MASRI, H. A; THOMAS, R. S; SABADOS, G. R et al.Archives of toxicology. 1996, Vol 70, Num 11, pp 704-713, issn 0340-5761Article

Physiologically based pharmacodynamic modeling of an interaction threshold between trichloroethylene and 1,1-dichloroethylene in Fischer 344 ratsEL-MASRI, H. A; CONSTAN, A. A; RAMSDELL, H. S et al.Toxicology and applied pharmacology. 1996, Vol 141, Num 1, pp 124-132, issn 0041-008XArticle

The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixturesYANG, R. S. H; EL-MASRI, H. A; THOMAS, R. S et al.Toxicology letters. 1995, Vol 79, Num 1-3, pp 193-200, issn 0378-4274Conference Paper

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