The effects of accumulation of an environmentally relevant polychlorinated biphenyl mixture on cytochrome P450 and P-glycoprotein expressions in fetuses and pregnant ratsBONFANTI, Patrizia; COLOMBO, Anita; VILLA, Sara et al.Chemosphere (Oxford). 2009, Vol 75, Num 5, pp 572-579, issn 0045-6535, 8 p.Article

Antihyperalgesic Effect of a Cannabis sativa Extract in a Rat Model of Neuropathic Pain : Mechanisms InvolvedCOMELLI, Francesca; GIAGNONI, Gabriella; BETTONI, Isabella et al.PTR. Phytotherapy research. 2008, Vol 22, Num 8, pp 1017-1024, issn 0951-418X, 8 p.Article

The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain : involvement of CB₁, TRPV1 and PPARy receptors and neurotrophic factorsCOSTA, Barbara; COMELLI, Francesca; BETTONI, Isabella et al.Pain (Amsterdam). 2008, Vol 139, Num 3, pp 541-550, issn 0304-3959, 10 p.Article

AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic painCOSTA, Barbara; SINISCALCO, Dario; TROVATO, Anna Elisa et al.British journal of pharmacology. 2006, Vol 148, Num 7, pp 1022-1032, issn 0007-1188, 11 p.Article

Novel imidazoline compounds as partial or full agonists of D₂-like dopamine receptors inspired by I₂-imidazoline binding sites ligand 2-BFIGIORGIONI, Gianfabio; AMBROSINI, Dario; CARRIERI, Antonio et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 19, pp 7085-7091, issn 0968-0896, 7 p.Article

CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activationZANONI, Ivan; OSTUNI, Renato; COSTA, Barbara et al.Nature (London). 2009, Vol 460, Num 7252, pp 264-268, issn 0028-0836, 5 p.Article

5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A₁ adenosine receptor agonists : Affinity, efficacy, and selectivity for A₁ receptor from different speciesCAPPELLACCI, Loredana; FRANCHETTI, Palmarisa; VITA, Patrizia et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 1, pp 336-353, issn 0968-0896, 18 p.Article

The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1β, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in miceMARTUCCI, Cataldo; ELISA TROVATO, Anna; COLLEONI, Mariapia et al.Pain (Amsterdam). 2008, Vol 137, Num 1, pp 81-95, issn 0304-3959, 15 p.Article

Synthesis and benzodiazepine receptor affinity of pyrazolo[1,5-a]pyrimidine derivatives. 3. New 6-(3-thienyl) series as α1 selective ligandsSELLERI, Silvia; BRUNI, Fabrizio; RENARD, Stephane et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 2, pp 310-313, issn 0022-2623, 4 p.Article

Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligandsDI STEFANO, Antonio; SOZIO, Piera; LUISI, Grazia et al.Il Farmaco (Pavia). 2002, Vol 57, Num 4, pp 303-313, issn 0014-827XArticle

Synthesis and preliminary pharmacological evaluation of 5-hydroxy- and 5,6-dihydroxy-1,2,3,7,12,12a-hexahydrobenzo [5,6]cyclohepta[1,2,3-ij]isoquinoline derivatives as dopamine receptor ligandsCINGOLANI, Gian Mario; DI STEFANO, Antonio; COSTA, Barbara et al.Bioorganic & medicinal chemistry. 2001, Vol 9, Num 6, pp 1447-1458, issn 0968-0896Article

Chronic treatment with the endocannabinoid anandamide increases cytochrome P450 metabolizing system in the ratCOSTA, Barbara; PAROLARO, Daniela; COLLEONI, Mariapia et al.European journal of pharmacology. 2002, Vol 449, Num 1-2, pp 61-69, issn 0014-2999Article

Endocannabinoids: A unique opportunity to develop multitarget analgesicsMAIONE, Sabatino; COSTA, Barbara; DI MARZO, Vincenzo et al.Pain (Amsterdam). 2013, Vol 154, issn 0304-3959, S87-S93, SUP1Article

Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene) sulfonamido-based hydroxamates as matrix metalloproteinase inhibitorsNUTI, Elisa; CASALINI, Francesca; MARGARIDA BERNARDO, M et al.European journal of medicinal chemistry. 2011, Vol 46, Num 7, pp 2617-2629, issn 0223-5234, 13 p.Article

Rimonabant, a cannabinoid CB₁ receptor antagonist, attenuates mechanical allodynia and counteracts oxidative stress and nerve growth factor deficit in diabetic miceCOMELLI, Francesca; BETTONI, Isabella; COLOMBO, Anita et al.European journal of pharmacology. 2010, Vol 637, Num 1-3, pp 62-69, issn 0014-2999, 8 p.Article

The plant cannabinoid Δ⁹-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in miceBOLOGNINI, Daniele; COSTA, Barbara; PERTWEE, Roger G et al.British journal of pharmacology. 2010, Vol 160, Num 3, pp 677-687, issn 0007-1188, 11 p.Article

Peripheral benzodiazepine receptor ligands: mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cellsCHELLI, Beatrice; LENA, Annalisa; GREMIGNI, Vittorio et al.Biochemical pharmacology. 2004, Vol 68, Num 1, pp 125-134, issn 0006-2952, 10 p.Article

Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammationCOSTA, Barbara; GIAGNONI, Gabriella; FRANKE, Chiara et al.British journal of pharmacology. 2004, Vol 143, Num 2, pp 247-250, issn 0007-1188, 4 p.Article

ET_A receptor-mediated Ca²⁺ mobilisation in H9c2 cardiac cellsCECCARELLI, Francesca; SCAVUZZO, Maria C; GIUSTI, Laura et al.Biochemical pharmacology. 2003, Vol 65, Num 5, pp 783-793, issn 0006-2952, 11 p.Article

A_2A adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosisTRINCAVELLI, Maria L; FALLENI, Alessandra; CHELLI, Beatrice et al.Biochemical pharmacology. 2003, Vol 66, Num 10, pp 1953-1962, issn 0006-2952, 10 p.Article

erythro- and threo-2-Hydroxynonyl substituted 2-phenyladenines and 2-phenyl-8-azaadenines: ligands for A₁ adenosine receptors and adenosine deaminaseBIAGI, Giuliana; GIORGI, Irene; LIVI, Oreste et al.Il Farmaco (Pavia). 2002, Vol 57, Num 3, pp 221-233, issn 0014-827XArticle

Novel N-(arylalkyl)indol-3-ylglyoxylylamides targeted as ligands of the benzodiazepine receptor: Synthesis, biological evaluation, and molecular modeling analysis of the structure-activity relationshipsPRIMOFIORE, Giampaolo; DA SETTIMO, Federico; MARTINI, Claudia et al.Journal of medicinal chemistry (Print). 2001, Vol 44, Num 14, pp 2286-2297, issn 0022-2623Article

Iminosugar Analogues of Phosphatidyl Inositol as Potential Inhibitors of Protein Kinase B (Akt)ORSATO, Alexandre; BARBAGALLO, Emanuela; COSTA, Barbara et al.European journal of organic chemistry (Print). 2011, Num 26, pp 5012-5019, issn 1434-193X, 8 p.Article

Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABA_A) α₂ Benzodiazepine ReceptorTALIANI, Sabrina; COSIMELLI, Barbara; MARINELLI, Luciana et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 12, pp 3723-3734, issn 0022-2623, 12 p.Article

The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic painCOSTA, Barbara; TROVATO, Anna Elisa; COMELLI, Francesca et al.European journal of pharmacology. 2007, Vol 556, Num 1-3, pp 75-83, issn 0014-2999, 9 p.Article