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Results 1 to 25 of 855

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Enhancement of Radiation-induced DNA Damage and Inhibition of Its Repair by a Novel Camptothecin AnalogGE HUANG; HUIJUAN WANG; YANG, Li-Xi et al.Anticancer research. 2010, Vol 30, Num 3, pp 937-944, issn 0250-7005, 8 p.Article

A TOTAL SYNTHESIS OF CAMPTOTHECIN AND DEETHYLDEOXYCAMPTOTHECINMEYERS AI; NOLEN RL; COLLINGTON EW et al.1973; J. ORG. CHEM.; U.S.A.; DA. 1973; VOL. 38; NO 11; PP. 1974-1982; BIBL. 28 REF.Serial Issue

REAKTIONEN AN INDOLDERIVATEN. XXVIII. ALKYLIERUNG VON CAMPTOTHECIN-VORSTUFEN - EIN NEUER WEG ZUM CAMPTOTHECIN = REACTIONS DES DERIVES DE L'INDOLE. XXVIII. ALKYLATION D'INTERMEDIAIRES DE CAMPTOTHECINE, UNE NOUVELLE VOIE D'ACCES A LA CAMPTOTHECINEKROHN K; WINTERFELDT E.1975; CHEM. BER.; DTSCH.; DA. 1975; VOL. 108; NO 9; PP. 3030-3042; ABS. ANGL.; BIBL. 11 REF.Article

Renal Function as a Predictor of Irinotecan-induced NeutropeniaDE JONG, F. A; VAN DER BOL, J. M; MATHIJSSEN, R. H. J et al.Clinical pharmacology and therapeutics. 2008, Vol 84, Num 2, pp 254-262, issn 0009-9236, 9 p.Article

Clinical Determinants of Response to Irinotecan-Based Therapy Derived from Cell Line ModelsALLEN, Wendy L; COYLE, Vicky M; JOHNSTON, Patrick G et al.Clinical cancer research (Print). 2008, Vol 14, Num 20, pp 6647-6655, issn 1078-0432, 9 p.Article

Irinotecan Pharmacogenetics : Influence of Pharmacodynamic GenesHOSKINS, Janelle M; MARCUELLO, Eugenio; ALTES, Albert et al.Clinical cancer research. 2008, Vol 14, Num 6, pp 1788-1796, issn 1078-0432, 9 p.Article

Transport characteristics of 9-nitrocamptothecin in the human intestinal cell line Caco-2 and everted gut sacsXIANYI SHA; XIAOLING FANG.International journal of pharmaceutics. 2004, Vol 272, Num 1-2, pp 161-171, issn 0378-5173, 11 p.Article

Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effectsSAPRA, Puja; KRAFT, Patricia; PASTORINO, Fabio et al.Angiogenesis (London). 2011, Vol 14, Num 3, pp 245-253, issn 0969-6970, 9 p.Article

A novel method to load topotecan into liposomes driven by a transmembrane NH4EDTA gradientYUEHUI YANG; YANLING MA; SHAONING WANG et al.European journal of pharmaceutics and biopharmaceutics. 2012, Vol 80, Num 2, pp 332-339, issn 0939-6411, 8 p.Article

Pharmacogenetic Pathway Analysis of IrinotecanROSNER, G. L; PANETTA, J. C; INNOCENTI, F et al.Clinical pharmacology and therapeutics. 2008, Vol 84, Num 3, pp 393-402, issn 0009-9236, 10 p.Article

Targeting atypical trypanosomatid DNA topoisomerase IBALANA-FOUCE, Rafael; REDONDO, Carmen M; PEREZ-PERTEJO, Yolanda et al.Drug discovery today. 2006, Vol 11, Num 15, pp 733-740, issn 1359-6446, 8 p.Article

Validation study of assay method for DE-310, a novel polymer-bound camptothecin derivative, and the free drug in mouse plasma by liquid chromatography with fluorimetric detectionOGUMA, Toshihiro; KONNO, Tomomi; NAKAOKA, Minoru et al.Journal of chromatography. B. 2004, Vol 801, Num 2, pp 157-164, issn 1570-0232, 8 p.Article

Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicityCAO, Shousong; DURRANI, Farukh A; RUSTUM, Youcef M et al.Cancer chemotherapy and pharmacology. 2012, Vol 69, Num 4, pp 1107-1111, issn 0344-5704, 5 p.Article

The Role of the Transition Metal Copper and the lonophore A23187 in the Development of Irinophore CT™PATANKAR, Nilesh; ANANTHA, Malathi; RAMSAY, Euan et al.Pharmaceutical research. 2011, Vol 28, Num 4, pp 848-857, issn 0724-8741, 10 p.Article

Formulation and Comparative Characterization of Chitosan, Gelatin, and Chitosan-Gelatin-Coated Liposomes of CPT-11-HCISHENDE, Pravin; GAUD, Ram.Drug development and industrial pharmacy. 2009, Vol 35, Num 5, pp 612-618, issn 0363-9045, 7 p.Article

Irinotecan plus carboplatin for patients with carcinoma of unknown primary siteYONEMORI, K; ADO, M; YAMANAKA, Y et al.British journal of cancer. 2009, Vol 100, Num 1, pp 50-55, issn 0007-0920, 6 p.Article

A Phase 1 Dose-Escalation Study of Irinotecan in Combination with 17-Allylamino-17-Demethoxygeldanamycin in Patients with Solid TumorsTSE, Archie N; KLIMSTRA, David S; KI CHUNG et al.Clinical cancer research (Print). 2008, Vol 14, Num 20, pp 6704-6711, issn 1078-0432, 8 p.Article

P-Glycoprotein and Breast Cancer Resistance Protein : Two Dominant Transporters Working Together in Limiting the Brain Penetration of TopotecanDEVRIES, Nienkea; JIN ZHAO; KROON, Emily et al.Clinical cancer research. 2007, Vol 13, Num 21, pp 6440-6449, issn 1078-0432, 10 p.Article

Optimization of irinotecan chronotherapy with P-glycoprotein inhibitionFILIPSKI, Elisabeth; BERLAND, Elodie; OZTURK, Narin et al.Toxicology and applied pharmacology. 2014, Vol 274, Num 3, pp 471-479, issn 0041-008X, 9 p.Article

Effect of radiation on the penetration of irinotecan in rat cerebrospinal fluidKHATRI, Amit; GABER, M. Waleed; BRUNDAGE, Richard C et al.Cancer chemotherapy and pharmacology. 2011, Vol 68, Num 3, pp 721-731, issn 0344-5704, 11 p.Article

Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphismsSATOH, Taroh; URA, Takashi; KOIZUMI, Wasaburo et al.Cancer science. 2011, Vol 102, Num 10, pp 1868-1873, issn 1347-9032, 6 p.Article

A Semi-physiological-Based Pharmacokinetic/Pharmacodynamic Model to Describe the Effects of Topotecan on B-Lymphocyte Lineage CellsVELEZ DE MENDIZABAL, Nieves; MARTINEZ-FORERO, Iván; GARRIDO, María J et al.Pharmaceutical research. 2010, Vol 27, Num 3, pp 431-441, issn 0724-8741, 11 p.Article

Development of a highly stable and targetable nanoliposomal formulation of topotecanDRUMMOND, Daryl C; NOBLE, Charles O; BENZ, Christopher C et al.Journal of controlled release. 2010, Vol 141, Num 1, pp 13-21, issn 0168-3659, 9 p.Article

Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal FluidJUN SHEN; CARCABOSO, Angel M; HUBBARD, K. Elaine et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 14, pp 5885-5892, issn 0008-5472, 8 p.Article

Determination of total and lactone form of a new camptothecin derivative gimatecan (ST1481) and its metabolite ST1698 in human plasma by high-performance liquid chromatography with fluorimetric detectionPACE, Silvia; CAPOCASA, Francesca; TALLARICO, Carlo et al.Journal of pharmaceutical and biomedical analysis. 2009, Vol 50, Num 3, pp 507-514, issn 0731-7085, 8 p.Article

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