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Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors: Analogues of SAD-128MUSILEK, Kamil; RODER, Jan; KOMLOOVA, Marketa et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 1, pp 150-154, issn 0960-894X, 5 p.Article

Synthesis and biological activity of a novel class nicotinic acetylcholine receptors (nAChRs) ligands structurally related to anatoxin-aSIMONI, Daniele; RONDANIN, Riccardo; VIRGINIO, Caterina et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 18, pp 5423-5427, issn 0960-894X, 5 p.Article

Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M5 PAMBRIDGES, Thomas M; KENNEDY, J. Phillip; CHO, Hyekyung P et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 2, pp 558-562, issn 0960-894X, 5 p.Article

In silico characterization of cytisinoids docked into an acetylcholine binding proteinABIN-CARRIQUIRY, Juan Andrés; PAULINO ZUNINI, Margot; CASSELS, Bruce K et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 12, pp 3683-3687, issn 0960-894X, 5 p.Article

Synthesis and SAR of N-(4-(4-alklylpiperazin-1-yl)phenyl)benzamides as muscarinic acetylcholine receptor subtype 1 (M1) anatgonistsMILLER, Nicole R; DANIELS, R. Nathan; LEE, David et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 7, pp 2174-2177, issn 0960-894X, 4 p.Article

Identification of 9-fluoro substituted (-)-cytisine derivatives as ligands with high affinity for nicotinic receptorsHOULLIER, Nicolas; GOPISETTI, Jaganmohan; LESTAGE, Pierre et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 22, pp 6667-6670, issn 0960-894X, 4 p.Article

3D-QSAR studies of 2,2-diphenylpropionates to aid discovery of novel potent muscarinic antagonistsBHATTACHARJEE, Apurba K; GORDON, Jonathan A; MAREK, Elizabeth et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 11, pp 3999-4012, issn 0968-0896, 14 p.Article

Structure and Activity of (2,8)-Dicarba-(3,12)-cystino α-ImI, an α-Conotoxin Containing a Nonreducible Cystine AnalogueMACRAILD, Christopher A; ILLESINGHE, Jayamini; VAN LIEROP, Bianca J et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 3, pp 755-762, issn 0022-2623, 8 p.Article

Use of Acetylcholine Binding Protein in the Search for Novel a7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray AnalysisULENS, Chris; AKDEMIR, Atilla; DE ESCH, Iwan J. P et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 8, pp 2372-2383, issn 0022-2623, 12 p.Article

Design of novel α7-subtype-preferring nicotinic acetylcholine receptor agonists: Application of docking and MM-PBSA computational approaches, synthetic and pharmacological studiesGRAZIOSO, Giovanni; DIEGO YURI POME; CARLO MATERA et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 22, pp 6353-6357, issn 0960-894X, 5 p.Article

The synthesis of 5-substituted ring E analogs of methyllycaconitine via the Suzuki-Miyaura cross-coupling reactionJUNFENG HUANG; ORAC, Crina M; MCKAY, Susan et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 7, pp 3816-3824, issn 0968-0896, 9 p.Article

Bis-Pyridinium cyclophanes : Novel ligands with high affinity for the blood-brain barrier choline transporterZHENFA ZHANG; LOCKMAN, Paul R; MITTAPALLI, Rajendar K et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 20, pp 5622-5625, issn 0960-894X, 4 p.Article

Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant α4β2 nicotinic acetylcholine receptor potentiatorsALBRECHT, Brian K; BERRY, Virginia; KNOP, Johannes et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 19, pp 5209-5212, issn 0960-894X, 4 p.Article

Synthesis and activity of substituted carbamates as potentiators of the α4β2 nicotinic acetylcholine receptorSPRINGER, Stephanie K; WOODIN, Katrina S; MCDERMOTT, Jeff S et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 20, pp 5643-5647, issn 0960-894X, 5 p.Article

Enantiomeric N-methyl-4-piperidyl benzilates as muscarinic receptor ligands : Radioligand binding studies and docking studies to models of the three muscarinic receptors M1, M2 and M3SELENT, Jana; BRANDT, Wolfgang; PAMPERIN, Dirk et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 6, pp 1729-1736, issn 0968-0896, 8 p.Article

Novel tricyclic quinazolinimines and related tetracyclic nitrogen bridgehead compounds as cholinesterase inhibitors with selectivity towards butyrylcholinesteraseDECKER, Michael; KRAUTH, Fabian; LEHMANN, Jochen et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 6, pp 1966-1977, issn 0968-0896, 12 p.Article

Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanesCARROLL, F. Ivy; XINGDING HU; NAVARRO, Hernan A et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 11, pp 3244-3250, issn 0022-2623, 7 p.Article

6-(2-phenylethyl)nicotine : A novel nicotinic cholinergic receptor ligandRAMUNNO, Anna; DUKAT, Malgorzata; LEE, Mase et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 13, pp 3237-3240, issn 0960-894X, 4 p.Article

Design of novel nicotinic ligands through 3D database searchingGUANDALINI, Luca; MARTINI, Elisabetta; NOVELLINO, Ettore et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 3, pp 799-807, issn 0968-0896, 9 p.Article

Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing β2 subunitsWEI, Zhi-Liang; YINGXIAN XIAO; HONGBIN YUAN et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 6, pp 1721-1724, issn 0022-2623, 4 p.Article

N-8-Substituted benztropinamine analogs as selective dopamine transporter ligandsGRUNDT, Peter; KOPAJTIC, Theresa A; KATZ, Jonathan L et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 24, pp 5419-5423, issn 0960-894X, 5 p.Article

Synthesis and chemiluminescent high throughput screening for inhibition of acetylcholinesterase activity by imidazo[2,1-b]thiazole derivativesANDREANI, Aldo; GRANAIOLA, Massimiliano; GUARDIGLI, Massimo et al.European journal of medicinal chemistry. 2005, Vol 40, Num 12, pp 1331-1334, issn 0223-5234, 4 p.Article

In vitro and in vivo characterization of TC-1827, a novel brain α4β2 nicotinic receptor agonist with pro-cognitive activityBOHME, Georg Andrees; LETCHWORTH, Sharon R; GENEVOIS-BORELLA, Arielle et al.Drug development research. 2004, Vol 62, Num 1, pp 26-40, issn 0272-4391, 15 p.Article

A large, community-based, open-label trial of donepezil in the treatment of Alzheimer's diseaseRELKIN, Norman R; REICHMAN, William E; ORAZEM, John et al.Dementia and geriatric cognitive disorders. 2003, Vol 16, Num 1, pp 15-24, issn 1420-8008, 10 p.Article

An open-label extension trial of galantamine in patients with probable vascular dementia and mixed dementiaERKINJUNTTI, Timo; KURZ, Alexander; SMALL, Gary W et al.Clinical therapeutics. 2003, Vol 25, Num 6, pp 1765-1782, issn 0149-2918, 18 p.Article

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