Thr302 Is the Site for the Covalent Modification of Human Cytochrome P450 2B6 Leading to Mechanism-Based Inactivation by tert-ButylphenylacetyleneLIN, Hsia-Lien; HAOMING ZHANG; PRATT-HYATT, Matthew J et al.Drug metabolism and disposition. 2011, Vol 39, Num 12, pp 2431-2439, issn 0090-9556, 9 p.Article

Decreased Susceptibility of the Cytochrome P450 2B6 Variant K262R to Inhibition by Several Clinically Important DrugsTALAKAD, Jyothi C; KUMAR, Santosh; HALPERT, James R et al.Drug metabolism and disposition. 2009, Vol 37, Num 3, pp 644-650, issn 0090-9556, 7 p.Article

Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptorKÖHALMY, Krisztina; TAMASI, Viola; KOBORI, Laszio et al.Drug metabolism and disposition. 2007, Vol 35, Num 9, pp 1495-1501, issn 0090-9556, 7 p.Article

Anandamide Oxidation by Wild-Type and Polymorphically Expressed CYP2B6 and CYP2D6SRIDAR, Chitra; SNIDER, Natasha T; HOLLENBERG, Paul F et al.Drug metabolism and disposition. 2011, Vol 39, Num 5, pp 782-788, issn 0090-9556, 7 p.Article

Human hepatic CYP2B6 developmental expression: The impact of age and genotypeCROOM, Edward L; STEVENS, Jeffrey C; HINES, Ronald N et al.Biochemical pharmacology. 2009, Vol 78, Num 2, pp 184-190, issn 0006-2952, 7 p.Article

Mechanistic Analysis of the Inactivation of Cytochrome P450 2B6 by Phencyclidine : Effects on Substrate Binding, Electron Transfer, and UncouplingSHEBLEY, Mohamad; KENT, Ute M; BALLOU, David P et al.Drug metabolism and disposition. 2009, Vol 37, Num 4, pp 745-752, issn 0090-9556, 8 p.Article

ATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6 : Implications in Hepatic Stress ResponsesPASCUAL, Maya; GOMEZ-LECHON, M. Jose; CASTELL, José V et al.Drug metabolism and disposition. 2008, Vol 36, Num 6, pp 1063-1072, issn 0090-9556, 10 p.Article

Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytesAITKEN, Alison E; MORGAN, Edward T.Drug metabolism and disposition. 2007, Vol 35, Num 9, pp 1687-1693, issn 0090-9556, 7 p.Article

Effect of CYP2B6^*6 and CYP2C19^*2 genotype on chlorpyrifos metabolismCRANE, Alice L; KLEIN, Kathrin; ZANGER, Ulrich M et al.Toxicology (Amsterdam). 2012, Vol 293, Num 1-3, pp 115-122, issn 0300-483X, 8 p.Article

Human Pregnane X Receptor Activation and CYP3A4/CYP2B6 Induction by 2,3-Oxidosqualene:Lanosterol Cyclase InhibitionDUNIEC-DMUCHOWSKI, Zofia; FANG, Hai-Lin; STROM, Stephen C et al.Drug metabolism and disposition. 2009, Vol 37, Num 4, pp 900-908, issn 0090-9556, 9 p.Article

Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent ExpressionSUGATANI, Junko; OSABE, Makoto; KUROSAWA, Masatoshi et al.Drug metabolism and disposition. 2010, Vol 38, Num 1, pp 177-186, issn 0090-9556, 10 p.Article

Equine cytochrome P450 2B6 ― Genomic identification, expression and functional characterization with ketaminePETERS, L. M; DEMMEL, S; PUSCH, G et al.Toxicology and applied pharmacology. 2013, Vol 266, Num 1, pp 101-108, issn 0041-008X, 8 p.Article

Effects of woohwangcheongsimwon suspension on the pharmacokinetics of bupropion and its active metabolite, 4-hydroxybupropion, in healthy subjectsKIM, Hyunmi; SOO KYUNG BAE; PARK, Soo-Jin et al.British journal of clinical pharmacology. 2010, Vol 70, Num 1, pp 126-131, issn 0306-5251, 6 p.Article

Inhibition of Human CYP2B6-Catalyzed Bupropion Hydroxylation by Ginkgo biloba Extract: Effect of Terpene Trilactones and FlavonolsLAU, Aik Jiang; CHANG, Thomas K. H.Drug metabolism and disposition. 2009, Vol 37, Num 9, pp 1931-1937, issn 0090-9556, 7 p.Article

Cytochrome P450 2B6 and 2C9 genotype polymorphism - a possible cause of prasugrel low responsivenessFRANKEN, Cora C; KAISER, Andreas F. C; KRÜGER, Jan C et al.Thrombosis and haemostasis. 2013, Vol 110, Num 1, pp 131-140, issn 0340-6245, 10 p.Article

CYP2B6 genotype does not alter nicotine metabolism, plasma levels, or abstinence with nicotine replacement therapyLEE, Anna M; JEPSON, Christopher; SHIELDS, Peter G et al.Cancer epidemiology, biomarkers & prevention. 2007, Vol 16, Num 6, pp 1312-1314, issn 1055-9965, 3 p.Article

A comparison of 2-phenyl-2-(1-piperidinyl)propane (PPP), 1,1',1-phosphinothioylidynetrisaziridine (ThioTEPA), clopidogrel, and ticlopidine as selective inactivators of human cytochrome P450 2B6WALSKY, Robert L; OBACH, R. Scott.Drug metabolism and disposition. 2007, Vol 35, Num 11, pp 2053-2059, issn 0090-9556, 7 p.Article

Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4TALAKAD, Jyothi C; SHAH, Manish B; WALKER, Gregory S et al.Drug metabolism and disposition. 2011, Vol 39, Num 3, pp 539-550, issn 0090-9556, 12 p.Article

Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR)ANDERSON, Linnea E; DRING, Ann M; HAMEL, Laura D et al.Toxicology letters. 2011, Vol 202, Num 2, pp 148-154, issn 0378-4274, 7 p.Article

CYP2B6*6 is associated with increased breast cancer riskJUSTENHOVEN, Christina; PENTIMALLI, Daniela; PARK-SIMON, Tjoung-Won et al.International journal of cancer (Print). 2014, Vol 134, Num 2, pp 426-430, issn 0020-7136, 5 p.Article

The combined impact of CYP2C19 and CYP286 pharmacogenetics on cyclophosphamide bioactivationHELSBY, Nuala A; HUI, Chung-Yee; GOLDTHORPE, Michael A et al.British journal of clinical pharmacology. 2010, Vol 70, Num 6, pp 844-853, issn 0306-5251, 10 p.Article

Genetic variations of CYP2B6 gene were associated with plasma BPDE-Alb adducts and DNA damage levels in coke oven workersGUOXIANG HUANG; HUAN GUO; TANGCHUN WU et al.Toxicology letters. 2012, Vol 211, Num 3, pp 232-238, issn 0378-4274, 7 p.Article

Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptorCASABAR, Richard C. T; DAS, Parikshit C; DEKREY, Gregory K et al.Toxicology and applied pharmacology. 2010, Vol 245, Num 3, pp 335-343, issn 0041-008X, 9 p.Article

Influence of the Cytochrome P450 2B6 Genotype on Population Pharmacokinetics of Efavirenz in Human Immunodeficiency Virus PatientsCABRERA, Salvador E; SANTOS, Dolores; VALVERDE, Maria P et al.Antimicrobial agents and chemotherapy. 2009, Vol 53, Num 7, pp 2791-2798, issn 0066-4804, 8 p.Article

Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepaEKHART, Corine; DOODEMAN, Valerie D; RODENBUIS, Sjoerd et al.British journal of clinical pharmacology. 2009, Vol 67, Num 1, issn 0306-5251, 50-60, 145 [12 p.]Article