New insights into the function of GABA_A receptor subtypesREYNOLDS, David S; DAWSON, Gerard R.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, issn 0091-3057, 124 p.Serial Issue

Special issue on CNS Experimental MedicineDAWSON, Gerard R; DOURISH, Colin T; GOODWIN, Guy M et al.Journal of psychopharmacology (Oxford). 2011, Vol 25, Num 9, issn 0269-8811, 122 p.Serial Issue

The value of genetic and pharmacological approaches to understanding the complexities of GABA_A receptor subtype functions : The anxiolytic effects of benzodiazepinesREYNOLDS, David S.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 37-42, issn 0091-3057, 6 p.Article

GABA in the female brain : Oestrous cycle-related changes in GABAergic function in the periaqueductal grey matterLOVICK, T. A.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 43-50, issn 0091-3057, 8 p.Article

Strain-and model-dependent effects of chlordiazepoxide, L-838,417 and zolpidem on anxiety-like behaviours in laboratory miceMATHIASEN, L. S; MIRZA, N. R; RODGERS, R. J et al.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 19-36, issn 0091-3057, 18 p.Article

Regulation of cognition and symptoms of psychosis : Focus on GABA_A receptors and glycine transporter 1MÖHLER, Hanns; RUDOLPH, Uwe; BOISON, Detlev et al.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 58-64, issn 0091-3057, 7 p.Article

Assessment of modafinil on attentional processes in a five-choice serial reaction time test in the ratWATERS, Kerry A; BURNHAM, Katherine E; O'CONNOR, Desmond et al.Journal of psychopharmacology (Oxford). 2005, Vol 19, Num 2, pp 149-158, issn 0269-8811, 10 p.Article

3-heteroaryl-2-pyridones: Benzodiazepine site ligands with functional selectivity for α2/α3-subtypes of human GABA_A receptor-ion channelsCOLLINS, Ian; MOYES, Christopher; DAWSON, Gerard R et al.Journal of medicinal chemistry (Print). 2002, Vol 45, Num 9, pp 1887-1900, issn 0022-2623Article

Validation of experimental medicine methods in psychiatry: The P1 vital approach and experienceDAWSON, Gerard R; CRAIG, Kevin J; DOURISH, Colin T et al.Biochemical pharmacology. 2011, Vol 81, Num 12, pp 1435-1441, issn 0006-2952, 7 p.Article

The use of the EEG in measuring therapeutic drug action: focus on depression and antidepressantsALHAJ, Hamid; WISNIEWSKI, Grzegorz; MCALLISTER-WILLIAMS, R. Hamish et al.Journal of psychopharmacology (Oxford). 2011, Vol 25, Num 9, pp 1175-1191, issn 0269-8811, 17 p.Article

The plasma―occupancy relationship of the novel GABA_A receptor benzodiazepine site ligand, α5IA, is similar in rats and primatesATACK, John R; ENG, Wai-Si; GIBSON, Ray E et al.British journal of pharmacology. 2009, Vol 157, Num 5, pp 796-803, issn 0007-1188, 8 p.Article

GABA_A receptors and alcoholLOBO, Ingrid A; ADRON HARRIS, R.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 90-94, issn 0091-3057, 5 p.Article

3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues : High-affinity γ-aminobutyric acid-A benzodiazepine receptor ligands with α2, α3, and α5-subtype binding selectivity over α1CARLING, Robert W; MOORE, Kevin W; COOK, Susan M et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 7, pp 1807-1822, issn 0022-2623, 16 p.Article

Selective, orally active γ-aminobutyric Acid_A α5 receptor inverse agonists as cognition enhancersSTERNFELD, Francine; CARLING, Robert W; ATACK, John R et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 9, pp 2176-2179, issn 0022-2623, 4 p.Article

Identification of a novel, selective GABA_A a5 receptor inverse agonist which enhances cognitionCHAMBERS, Mark S; ATACK, John R; REEVE, Austin J et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 11, pp 2227-2240, issn 0022-2623, 14 p.Article

GABA-A receptors and the response to CO₂ inhalation : A translational trans-species model of anxiety?BAILEY, Jayne E; NUTT, David J.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 51-57, issn 0091-3057, 7 p.Article

Abuse and dependence liability of benzodiazepine-type drugs : GABA_A receptor modulation and beyondLICATA, Stephanie C; ROWLETT, James K.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 74-89, issn 0091-3057, 16 p.Article

Agomelatine facilitates positive versus negative affective processing in healthy volunteer modelsHARMER, Catherine J; DE BODINAT, Christian; DAWSON, Gerard R et al.Journal of psychopharmacology (Oxford). 2011, Vol 25, Num 9, pp 1159-1167, issn 0269-8811, 9 p.Article

Experimental medicine in drug addiction: towards behavioral, cognitive and neurobiological biomarkersDUKA, Theodora; CROMBAG, Hans S; STEPHENS, David N et al.Journal of psychopharmacology (Oxford). 2011, Vol 25, Num 9, pp 1235-1255, issn 0269-8811, 21 p.Article

Scopolamine disrupts hippocampat activity during allocentric spatial memory in humans: an fMRI study using a virtual reality analogue of the Morris Water MazeANTONOVA, Elena; PARSLOW, David; BRAMMER, Michael et al.Journal of psychopharmacology (Oxford). 2011, Vol 25, Num 9, pp 1256-1265, issn 0269-8811, 10 p.Article

Targeted deletion of the GABRA2 gene encoding a2-subunits of GABA_A receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbituratesDIXON, C. I; ROSAHL, T. W; STEPHENS, D. N et al.Pharmacology, biochemistry and behavior. 2008, Vol 90, Num 1, pp 1-8, issn 0091-3057, 8 p.Article

Anxiogenic properties of an inverse agonist selective for α3 subunit-containing GABA_A receptorsATACK, John R; HUTSON, Peter H; DAWSON, Gerard R et al.British journal of pharmacology. 2005, Vol 144, Num 3, pp 357-366, issn 0007-1188, 10 p.Article

7-(1,1-dimethylethyl)-6-(2-ethyl-2h-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine : A functionally selective γ-aminobutyric Acid_A (GABA_A) α2/α3-subtype selective agonist that exhibits potent anxiolytic activity but is not sedating in animal modelsCARLING, Robert W; MADIN, Andrew; MCKERNAN, Ruth M et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 23, pp 7089-7092, issn 0022-2623, 4 p.Article

The GABA-A β3 subunit mediates anaesthesia induced by etomidateO'MEARA, Gillian F; NEWMAN, Richard J; FRADLEY, Rosa L et al.Neuroreport (Oxford). 2004, Vol 15, Num 10, pp 1653-1656, issn 0959-4965, 4 p.Article

Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazin es and analogues as subtype-selective inverse agonists for the GABA_Aα5 benzodiazepine binding siteSTREET, Leslie J; STERNFELD, Francine; DAWSON, Gerard R et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 14, pp 3642-3657, issn 0022-2623, 16 p.Article