The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-α motif domain in thymic selection and T-cell activationSHUDAN SHEN; JASMINE LAU; MINGHUA ZHU et al.Blood. 2009, Vol 114, Num 1, pp 74-84, issn 0006-4971, 11 p.Article

Inhibition of tumor metastasis by a growth factor receptor bound protein 2 src homology 2 domain-binding antagonistGIUBEFLINO, Alessio; YANG GAO; LEE, Sunmin et al.Cancer research (Baltimore). 2007, Vol 67, Num 13, pp 6012-6016, issn 0008-5472, 5 p.Article

Role of the Brk SH3 domain in substrate recognitionHAOQUN QIU; MILLER, W. Todd.Oncogene (Basingstoke). 2004, Vol 23, Num 12, pp 2216-2223, issn 0950-9232, 8 p.Article

A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processesXIAOLEI ZHANG; PEIBIN YUE; FLETCHER, Steven et al.Biochemical pharmacology. 2010, Vol 79, Num 10, pp 1398-1409, issn 0006-2952, 12 p.Article

Oncogenic JAK2V617F requires an intact SH2-like domain for constitutive activation and induction of a myeloproliferative disease in miceGORANTLA, Sivahari P; DECHOW, Tobias N; GRUNDLER, Rebekka et al.Blood. 2010, Vol 116, Num 22, pp 4600-4611, issn 0006-4971, 12 p.Article

Role of the Src homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiationLINGGE LU; HOLMQVIST, Kristina; CROSS, Michael et al.Cell growth and differentiation. 2002, Vol 13, Num 3, pp 141-148, issn 1044-9523Article

Conformationally Constrained Peptides as Protein Tyrosine Kinase InhibitorsTIWARI, Rakesh K; PARANG, Keykavous.Current pharmaceutical design (Print). 2012, Vol 18, Num 20, pp 2852-2866, issn 1381-6128, 15 p.Article

Src homology domain-containing phosphatase 2 suppresses cellular senescence in glioblastomaSTURLA, L.-M; ZINN, P. O; NG, K et al.British journal of cancer. 2011, Vol 105, Num 8, pp 1235-1243, issn 0007-0920, 9 p.Article

Basic study on SH2 domain of Grb2 as a molecular probe for detection of RTK activationSAITO, Yuriko; FURUKAWA, Takako; ARANO, Yasushi et al.International journal of oncology. 2010, Vol 37, Num 2, pp 281-287, issn 1019-6439, 7 p.Article

Recent Progress of Src SH2 and SH3 Inhibitors as Anticancer AgentsLU, X.-L; CAO, X; LIU, X.-Y et al.Current medicinal chemistry. 2010, Vol 17, Num 12, pp 1117-1124, issn 0929-8673, 8 p.Article

Src homology 2 domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanismHUAZHANG AN; HONGMEI XU; MINGHUI ZHANG et al.Blood. 2005, Vol 105, Num 12, pp 4685-4692, issn 0006-4971, 8 p.Article

Inhibitors for proteins endowed with catalytic and non-catalytic activity which recognize pTyrCOSTANTINO, Luca; BARLOCCO, Daniela.Current medicinal chemistry. 2004, Vol 11, Num 20, pp 2725-2747, issn 0929-8673, 23 p.Article

The elucidation of novel SH2 binding sites on PLD2DI FULVIO, M; LEHMAN, N; LIN, X et al.Oncogene (Basingstoke). 2006, Vol 25, Num 21, pp 3032-3040, issn 0950-9232, 9 p.Article

Domain-specific function of ShcC docking protein in neuroblastoma cellsMIYAKE, Izumi; HAKOMORI, Yuko; MISU, Yoko et al.Oncogene (Basingstoke). 2005, Vol 24, Num 19, pp 3206-3215, issn 0950-9232, 10 p.Article

Possible dominant-negative mutation of the SHIP gene in acute myeloid leukemiaLUO, J-M; YOSHIDA, H; NAOE, T et al.Leukemia. 2003, Vol 17, Num 1, pp 1-8, issn 0887-6924, 8 p.Article

Band 3 is an anchor protein and a target for SHP-2 tyrosine phosphatase in human erythrocytesBORDIN, Luciana; BRUNATI, Anna Maria; DONELLA-DEANA, Arianna et al.Blood. 2002, Vol 100, Num 1, pp 276-282, issn 0006-4971Article

Potential disease targets for drugs that disrupt protein - protein interactions of Grb2 and crk family adaptors : Recent progress in atypical applications of cytokine and anti-cytokineFELLER, Stephan M; LEWITZKY, Marc.Current pharmaceutical design. 2006, Vol 12, Num 5, pp 529-548, issn 1381-6128, 20 p.Article

Development of L-3-aminotyrosine suitably protected for the synthesis of a novel nonphosphorylated hexapeptide with low-nanomolar Grb2-SH2 domain-binding affinitySONG, Yan-Li; ROLLER, Peter P; LONG, Ya-Qiu et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 12, pp 3205-3208, issn 0960-894X, 4 p.Article

STAT-3 Inhibitors: State of the Art and New Horizons for Cancer TreatmentLAVECCHIA, A; DI GIOVANNI, C; NOVELLINO, E et al.Current medicinal chemistry. 2011, Vol 18, Num 16, pp 2359-2375, issn 0929-8673, 17 p.Article

New syntheses of tetrazolylmethylphenylalanine and O-malonyltyrosine as pTyr mimetics for the design of STAT3 dimerization inhibitorsDOURLAT, Jennifer; VALENTIN, Bruno; LIU, Wang-Qing et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 14, pp 3943-3946, issn 0960-894X, 4 p.Article

Significance of glucose intolerance and SHIP2 expression in hepatocellular carcinoma patients with HCV infectionSUMIE, Shuji; KAWAGUCHI, Takumi; KOGA, Hironori et al.Oncology reports. 2007, Vol 18, Num 3, pp 545-552, issn 1021-335X, 8 p.Article

Arachidonic acid induces ERK activation via Src SH2 domain association with the epidermal growth factor receptorALEXANDER, L. D; DING, Y; ALAGARSAMY, S et al.Kidney international. 2006, Vol 69, Num 10, pp 1823-1832, issn 0085-2538, 10 p.Article

Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes : A hydrogen exchange mass spectrometry studyCATALINA, M. Isabel; FISCHER, Marcel J. E; DEKKER, Frank J et al.Journal of the American Society for Mass Spectrometry. 2005, Vol 16, Num 7, pp 1039-1051, issn 1044-0305, 13 p.Article

Design and synthesis of protein superfamily-targeted chemical libraries for lead identification and optimizationSHUTTLEWORTH, Stephen J; CONNORS, Richard V; JIASHENG FU et al.Current medicinal chemistry. 2005, Vol 12, Num 11, pp 1239-1281, issn 0929-8673, 43 p.Article

SHP1 expression in bone marrow biopsies of myelodysplastic syndrome patients : a new prognostic factorMENA-DURAN, Armando V; TOGO, Summanuna H; MUSTELIN, Tomas et al.British journal of haematology. 2005, Vol 129, Num 6, pp 791-794, issn 0007-1048, 4 p.Article