Therapeutic exploitation of the physiological and molecular genetic alterations in head and neck cancerLE, Quynh-Thu; GIACCIA, Amato J.Clinical cancer research. 2003, Vol 9, Num 12, pp 4287-4295, issn 1078-0432, 9 p.Article

Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditionsKAPER, Fiona; DORNHOEFER, Nadja; GIACCIA, Amato J et al.Cancer research (Baltimore). 2006, Vol 66, Num 3, pp 1561-1569, issn 0008-5472, 9 p.Article

Hypoxia, inflammation, and the tumor microenvironment in metastatic disease : Inflammation and CancerFINGER, Elizabeth C; GIACCIA, Amato J.Cancer metastasis reviews. 2010, Vol 29, Num 2, pp 285-293, issn 0167-7659, 9 p.Article

Lysyl oxidase mediates hypoxic control of metastasisERLER, Janine T; GIACCIA, Amato J.Cancer research (Baltimore). 2006, Vol 66, Num 21, pp 10238-10241, issn 0008-5472, 4 p.Article

Tumor hypoxia, the physiological link between Trousseau's syndrome (carcinoma-induced coagulopathy) and metastasisDENKO, Nicholas C; GIACCIA, Amato J.Cancer research (Baltimore). 2001, Vol 61, Num 3, pp 795-798, issn 0008-5472Article

Role of Carcinoma-Associated Fibroblasts and Hypoxia in Tumor ProgressionGIACCIA, Amato J; SCHIPANI, Ernestina.Current Topics in Microbiology and Immunology. 2010, Vol 345, pp 31-45, issn 0070-217X, 15 p.Article

The role of ATM and ATR in the cellular response to hypoxia and re-oxygenationHAMMOND, Ester M; GIACCIA, Amato J.DNA repair. 2004, Vol 3, Num 8-9, pp 1117-1122, issn 1568-7864, 6 p.Article

Inhibition of ATR leads to increased sensitivity to hypoxia/reoxygenationHAMMOND, Ester M; DORIE, Mary Jo; GIACCIA, Amato J et al.Cancer research (Baltimore). 2004, Vol 64, Num 18, pp 6556-6562, issn 0008-5472, 7 p.Article

Energy regulation : HIF MXles it up with the C-MYC powerhouseSUTPHIN, Patrick D; GIACCIA, Amato J; CHAN, Denise A et al.Developmental cell. 2007, Vol 12, Num 6, pp 845-846, issn 1534-5807, 2 p.Article

Hypoxia, gene expression, and metastasisCHAN, Denise A; GIACCIA, Amato J.Cancer metastasis reviews. 2007, Vol 26, Num 2, pp 333-339, issn 0167-7659, 7 p.Article

Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environmentPAPANDREOU, Ioanna; KRISHNA, Chaya; KAPER, Fiona et al.Cancer research (Baltimore). 2005, Vol 65, Num 8, pp 3171-3178, issn 0008-5472, 8 p.Article

Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrestHAMMOND, Ester M; GREEN, Susannah L; GIACCIA, Amato J et al.Mutation research. Fundamental and molecular mechanisms of mutagenesis. 2003, Vol 532, Num 1-2, pp 205-213, issn 1386-1964, 9 p.Article

Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancerYONGHUA ZHU; DENHARDT, David T; HONGBIN CAO et al.Oncogene (Basingstoke). 2005, Vol 24, Num 43, pp 6555-6563, issn 0950-9232, 9 p.Article

Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient miceBEDOGNI, Barbara; O'NEILL, Melony S; WELFORD, Scott M et al.Cancer research (Baltimore). 2004, Vol 64, Num 7, pp 2552-2560, issn 0008-5472, 9 p.Article

Control of lysyl oxidase activity through site-specific deuteration of lysinePESTOV, Nikolay B; OKKELMAN, Irina A; SHMANAI, Vadim V et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 1, pp 255-258, issn 0960-894X, 4 p.Article

SAR studies of 4-pyridyl heterocyclic anilines that selectively induce autophagic cell death in von Hippel-Lindau-deficient renal cell carcinoma cellsBONNET, Muriel; FLANAGAN, Jack U; CHAN, Denise A et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 11, pp 3347-3356, issn 0968-0896, 10 p.Article

Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cellsSUTPHIN, Patrick D; CHAN, Denise A; LI, James M et al.Cancer research (Baltimore). 2007, Vol 67, Num 12, pp 5896-5905, issn 0008-5472, 10 p.Article

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cellsGHOSH, Asish K; SHANAFELT, Tait D; SECRETO, Charla et al.Blood. 2009, Vol 113, Num 22, pp 5568-5574, issn 0006-4971, 7 p.Article

Angiogenesis is required for successful bone induction during distraction osteogenesisFANG, Tony D; SALIM, Ali; LONGAKER, Michael T et al.Journal of bone and mineral research (Print). 2005, Vol 20, Num 7, pp 1114-1124, issn 0884-0431, 11 p.Article

XBP1 is essential for survival under hypoxic conditions and is required for tumor growthROMERO-RAMIREZ, Lorenzo; HONGBIN CAO; LE, Quynh-Thu et al.Cancer research (Baltimore). 2004, Vol 64, Num 17, pp 5943-5947, issn 0008-5472, 5 p.Article

Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomasLE, Quynh-Thu; SUTPHIN, Patrick D; RAYCHAUDHURI, Soumya et al.Clinical cancer research. 2003, Vol 9, Num 1, pp 59-67, issn 1078-0432, 9 p.Article

The Role of Tumor Cell-Derived Connective Tissue Growth Factor (CTGF/CCN2) in Pancreatic Tumor GrowthBENNEWITH, Kevin L; XIN HUANG; HAM, Christine M et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 3, pp 775-784, issn 0008-5472, 10 p.Article

Validation of Lysyl Oxidase As a Prognostic Marker for Metastasis and Survival in Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Trial 90-03LE, Quynh-Thu; HARRIS, Jonathan; DICKER, Adam et al.Journal of clinical oncology. 2009, Vol 27, Num 26, pp 4281-4286, issn 0732-183X, 6 p.Article

Galectin-1 : A link between tumor hypoxia and tumor immune privilegeLE, Quynh-Thu; GONGYI SHI; GIACCIA, Amato J et al.Journal of clinical oncology. 2005, Vol 23, Num 35, pp 8932-8941, issn 0732-183X, 10 p.Article

VEGF-Independent Cell-Autonomous Functions of HIF-1α Regulating Oxygen Consumption in Fetal Cartilage Are Critical for Chondrocyte SurvivalMAES, Christa; ARALDI, Elisa; HAIGH, Katharina et al.Journal of bone and mineral research (Print). 2012, Vol 27, Num 3, pp 596-609, issn 0884-0431, 14 p.Article