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Results 1 to 25 of 118

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The 2006 bernard b. brodie award lecture CYP2E1GONZALEZ, Frank J.Drug metabolism and disposition. 2007, Vol 35, Num 1, pp 1-8, issn 0090-9556, 8 p.Article

Role of CYP1B1 in GlaucomaVASILIOU, Vasilis; GONZALEZ, Frank J.Annual review of pharmacology and toxicology. 2008, Vol 48, pp 333-358, issn 0362-1642, 26 p.Article

TNF-α regulates mouse fetal hepatic maturation induced by oncostatin M and extracellular matricesKAMIYA, Akihide; GONZALEZ, Frank J.Hepatology (Baltimore, Md.). 2004, Vol 40, Num 3, pp 527-536, issn 0270-9139, 10 p.Article

Cytochrome P450 and xenobiotic receptor humanized miceGONZALEZ, Frank J; YU, Ai-Ming.Annual review of pharmacology and toxicology. 2006, Vol 46, pp 41-64, issn 0362-1642, 24 p.Article

Role of the hepatocyte nuclear factor 4α in control of the pregnane X receptor during fetal liver developmentKAMIYA, Akihide; INOUE, Yusuke; GONZALEZ, Frank J et al.Hepatology (Baltimore, Md.). 2003, Vol 37, Num 6, pp 1375-1384, issn 0270-9139, 10 p.Article

LC-MS-based metabolomics in drug metabolismCHI CHEN; GONZALEZ, Frank J; IDLE, Jeffrey R et al.Drug metabolism reviews (Softcover ed.). 2007, Vol 39, Num 2-3, pp 581-597, issn 0360-2532, 17 p.Article

PPARα : Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferatorsGONZALEZ, Frank J; SHAH, Yatrik M.Toxicology (Amsterdam). 2008, Vol 246, Num 1, pp 2-8, issn 0300-483X, 7 p.Conference Paper

Hepatocyte-restricted constitutive activation of PPARα induces hepatoproliferation but not hepatocarcinogenesisQIAN YANG; SHINJI ITO; GONZALEZ, Frank J et al.Carcinogenesis (New York. Print). 2007, Vol 28, Num 6, pp 1171-1177, issn 0143-3334, 7 p.Article

Peroxisome proliferator-activated receptor-α and liver cancer : where do we stand?PETERS, Jeffrey M; CHEUNG, Connie; GONZALEZ, Frank J et al.Journal of molecular medicine (Berlin. Print). 2005, Vol 83, Num 10, pp 774-785, issn 0946-2716, 12 p.Article

CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazidJIE CHENG; KRAUSZ, Kristopher W; FENG LI et al.Toxicology and applied pharmacology. 2013, Vol 266, Num 2, pp 245-253, issn 0041-008X, 9 p.Article

Peroxisome Proliferator-Activated Receptors-α and -γ, and cAMP-Mediated Pathways, Control Retinol-Binding Protein-4 Gene Expression in Brown Adipose TissueROSELL, Meritxell; HONDARES, Elayne; VILLARROYA, Francesc et al.Endocrinology (Philadelphia). 2012, Vol 153, Num 3, pp 1162-1173, issn 0013-7227, 12 p.Article

Stromal adipocyte PPARγ protects against breast tumorigenesisSKELHORNE-GROSS, Graham; REID, Alexis L; APOSTOLI, Anthony J et al.Carcinogenesis (New York. Print). 2012, Vol 33, Num 7, pp 1412-1420, issn 0143-3334, 9 p.Article

Pretreatment by low-dose fibrates protects against acute free fatty acid-induced renal tubule toxicity by counteracting PPARα deteriorationTAKAHASHI, Kyoko; KAMIJO, Yuji; HORA, Kazuhiko et al.Toxicology and applied pharmacology. 2011, Vol 252, Num 3, pp 237-249, issn 0041-008X, 13 p.Article

Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in miceSIDA NIU; FENG LI; TAN, Dun-Xian et al.Journal of pineal research. 2010, Vol 49, Num 2, pp 106-114, issn 0742-3098, 9 p.Article

Differential Response to Trichloroethylene-Induced Hepatosteatosis in Wild-Type and PPARa-Humanized MiceDONI HIKMAT RAMDHAN; KAMIJIMA, Michihiro; NAKAJIMA, Tamie et al.Environmental health perspectives. 2010, Vol 118, Num 11, pp 1557-1563, issn 0091-6765, 7 p.Article

KLF4-dependent, PPARγ-induced expression of GPA33 in colon cancer cell linesRAGEUL, Julie; MOTTIER, Stéphanie; JARRY, Anne et al.International journal of cancer (Print). 2009, Vol 125, Num 12, pp 2802-2809, issn 0020-7136, 8 p.Article

PPARa attenuates the proinflammatory response in activated mesangial cellsKONO, Keiichi; KAMIJO, Yuji; HORA, Kazuhiko et al.American journal of physiology. Renal physiology. 2009, Vol 65, Num 2, issn 1931-857X, F328-F336Article

Cytochrome P450 Expression and Regulation in CYP3A4/CYP2D6 Double Transgenic Humanized MiceFELMLEE, Melanie A; LON, Hoi-Kei; GONZALEZ, Frank J et al.Drug metabolism and disposition. 2008, Vol 36, Num 2, pp 435-441, issn 0090-9556, 7 p.Article

Mouse lung CYP1A1 catalyzes the metabolic activation of 2 -amino -1 -methyl -6 -phenylimidazo [4,5 -b]pyridine (PhIP)XIAOCHAO MA; IDLE, Jeffrey R; MALFATTI, Michael A et al.Carcinogenesis (New York. Print). 2007, Vol 28, Num 3, pp 732-737, issn 0143-3334, 6 p.Article

Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-κB target gene expressionSHAH, Yatrik M; XIAOCHAO MA; MORIMURA, Keiichirou et al.American journal of physiology. Gastrointestinal and liver physiology. 2007, Vol 55, Num 4, issn 0193-1857, G1114-G1122Article

Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhRLEE, Chul-Ho; ITO, Yuki; YANAGIBA, Yukie et al.Toxicology (Amsterdam). 2007, Vol 238, Num 2-3, pp 147-156, issn 0300-483X, 10 p.Article

The pregnane X Receptor gene-humanized mouse : A model for investigating drug-drug interactions mediated by cytochromes P450 3AXIAOCHAO MA; SHAH, Yatrik; CHEUNG, Connie et al.Drug metabolism and disposition. 2007, Vol 35, Num 2, pp 194-200, issn 0090-9556, 7 p.Article

The CYP2E1-humanized transgenic mouse : Role of CYP2E1 in acetaminophen hepatotoxicityCHEUNG, Connie; YU, Ai-Ming; WARD, Jerrold M et al.Drug metabolism and disposition. 2005, Vol 33, Num 3, pp 449-457, issn 0090-9556, 9 p.Article

Reversal of liver fibrosis in aryl hydrocarbon receptor null mice by dietary vitamin A depletionANDREOLA, Fausto; CALVISI, Diego F; ELIZONDO, Guillermo et al.Hepatology (Baltimore, Md.). 2004, Vol 39, Num 1, pp 157-166, issn 0270-9139, 10 p.Article

Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscleNÖHAMMER, Christa; BRUNNER, Friedrich; WÖLKART, Gerald et al.Laboratory investigation. 2003, Vol 83, Num 2, pp 259-269, issn 0023-6837, 11 p.Article

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