Effect of 7-day exposure to midazolam on electroencephalogram pharmacodynamics in rats: a model to study multiple pharmacokinetic-pharmacodynamic relationships in individual animalsLAURIJSSENS, Bart E; GREENBLATT, David J.Journal of pharmacy and pharmacology. 2002, Vol 54, Num 1, pp 77-86, issn 0022-3573Article

Evaluation of Supermix as an in vitro model of human liver microsomal drug metabolismVENKATAKRISHNAN, Karthik; VON MOLTKE, Lisa L; GREENBLATT, David J et al.Biopharmaceutics & drug disposition. 2002, Vol 23, Num 5, pp 183-190, issn 0142-2782Article

Human drug metabolism and the cytochromes P450 : Application and relevance of in vitro modelsVENKATAKRISHNAN, Karthik; VON MOLTKE, Lisa L; GREENBLATT, David J et al.Journal of clinical pharmacology. 2001, Vol 41, Num 11, pp 1149-1179, issn 0091-2700Article

Apparent active transport of MDMA is not mediated by P-glycoprotein : A comparison with MDCK and Caco-2 monolayersBERTELSEN, Kirk M; GREENBLATT, David J; VON MOLTKE, Lisa L et al.Biopharmaceutics & drug disposition. 2006, Vol 27, Num 5, pp 219-227, issn 0142-2782, 9 p.Article

The influence of age and sex on the clearance of cytochrome P450 3A substratesCOTREAU, Monette M; VON MOLTKE, Lisa L; GREENBLATT, David J et al.Clinical pharmacokinetics. 2005, Vol 44, Num 1, pp 33-60, issn 0312-5963, 28 p.Article

Clinically important drug interactions with zopiclone, zolpidem and zaleplonHESSE, Leah M; VON MOLTKE, Lisa L; GREENBLATT, David J et al.CNS drugs. 2003, Vol 17, Num 7, pp 513-532, issn 1172-7047, 20 p.Article

Fexofenadine transport in Caco-2 cells: Inhibition with verapamil and ritonavirPERLOFF, Michael D; VON MOLTKE, Lisa L; GREENBLATT, David J et al.Journal of clinical pharmacology. 2002, Vol 42, Num 11, pp 1269-1274, issn 0091-2700, 6 p.Article

Effect of Obesity on the Pharmacokinetics of Drugs in HumansHANLEY, Michael J; ABERNETHY, Darrell R; GREENBLATT, David J et al.Clinical pharmacokinetics. 2010, Vol 49, Num 2, pp 71-87, issn 0312-5963, 17 p.Article

In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes P450: Role of CYP3A4 and CYP3A5PATKI, Kiran C; VON MOLTKE, Lisa L; GREENBLATT, David J et al.Drug metabolism and disposition. 2003, Vol 31, Num 7, pp 938-944, issn 0090-9556, 7 p.Article

Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoproteinVISHNUVARDHAN, Daesety; VON MOLTKE, Lisa L; RICHERT, Clemens et al.AIDS (London). 2003, Vol 17, Num 7, pp 1092-1094, issn 0269-9370, 3 p.Article

Pharmacokinetics of Zolpidem from Sublingual Zolpidem Tartrate Tablets In Healthy Elderly Versus Non-Elderly SubjectsGREENBLATT, David J; HARMATZ, Jerold S; SINGH, Nikhilesh N et al.Drugs & aging. 2014, Vol 31, Num 10, pp 731-736, issn 1170-229X, 6 p.Article

Comparison of Pharmacokinetic Profiles of Zolpidem Buffered Sublingual Tablet and Zolpidem Oral Immediate-Release Tablet: Results from a Single-Center, Single-Dose, Randomized, Open-Label Crossover Study in Healthy AdultsGREENBLATT, David J; HARMATZ, Jerold S; ROTH, Thomas et al.Clinical therapeutics. 2013, Vol 35, Num 5, pp 604-611, issn 0149-2918, 8 p.Article

Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity : Comparison of wild-type and Cyp2e1(-/-) miceWOLF, Kristina K; WOOD, Sheryl G; VON MOLTKE, Lisa L et al.Drug metabolism and disposition. 2007, Vol 35, Num 7, pp 1223-1231, issn 0090-9556, 9 p.Article

Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteersPRESKORN, H; GREENBLATT, David J; FLOCKHART, David et al.Journal of clinical psychopharmacology. 2007, Vol 27, Num 1, pp 28-34, issn 0271-0749, 7 p.Article

Dose-dependent retrograde facilitation of verbal memory in healthy elderly after acute oral lorazepam administrationPOMARA, Nunzio; FACELLE, Thomas M; ROTH, Amy E et al.Psychopharmacologia. 2006, Vol 185, Num 4, pp 487-494, issn 0033-3158, 8 p.Article

The effect of chronic lorazepam administration in aging miceFAHEY, Jeanne M; PRITCHARD, Gary A; REDDI, Jyoti M et al.Brain research. 2006, Vol 1118, pp 13-24, issn 0006-8993, 12 p.Article

Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for udp-glucuronosyltransferase 1A6KRISHNASWAMY, Soundararajan; QIN HAO; VON MOLTKE, Lisa L et al.Drug metabolism and disposition. 2004, Vol 32, Num 8, pp 862-869, issn 0090-9556, 8 p.Article

Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6KRISHNASWAMY, Soundararajan; DUAN, Su X; VON MOLTKE, Lisa L et al.Drug metabolism and disposition. 2003, Vol 31, Num 1, pp 133-139, issn 0090-9556, 7 p.Article

Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell cultureSTÖRMER, Elke; VON MOLTKE, Lisa L; PERLOFF, Michael D et al.Pharmaceutical research. 2002, Vol 19, Num 7, pp 1038-1045, issn 0724-8741Article

Pharmacodynamic and receptor binding changes during chronic lorazepam administrationFAHEY, Jeanne M; PRITCHARD, Gary A; GRASSI, Jeffrey M et al.Pharmacology, biochemistry and behavior. 2001, Vol 69, Num 1-2, pp 1-8, issn 0091-3057Article

Role of NADPH-Cytochrome P450 Reductase and Cytochrome-b₅/ NADH-b₅ Reductase in Variability of CYP3A Activity in Human Liver MicrosomesLU GAN; VON MOLTKE, Lisa L; TREPANIER, Lauren A et al.Drug metabolism and disposition. 2009, Vol 37, Num 1, pp 90-96, issn 0090-9556, 7 p.Article

Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole : In vitro and clinical studiesGREENBLATT, David J; VON MOLTKE, Lisa L; PERLOFF, Elke Störmer et al.Clinical pharmacology and therapeutics. 2006, Vol 79, Num 1, pp 125-133, issn 0009-9236, 9 p.Article

Simple and rapid liquid chromatography method for determination of efavirenz in plasmaRAMACHANDRAN, Geetha; HEMANTH KUMAR, A. K; SWAMINATHAN, Soumya et al.Journal of chromatography. B. 2006, Vol 835, Num 1-2, pp 131-135, issn 1570-0232, 5 p.Article

Fluvoxamine impairs single-dose caffeine clearance without altering caffeine pharmacodynamicsCULM-MERDEK, Kerry E; VON MOLTKE, Lisa L; HARMATZ, Jerold S et al.British journal of clinical pharmacology. 2005, Vol 60, Num 5, pp 486-493, issn 0306-5251, 8 p.Article

Sex-related elevation in cortisol during chronic treatment with alprazolam associated with enhanced cognitive performancePOMARA, Nunzio; WILLOUGHBY, Lisa M; RITCHIE, James C et al.Psychopharmacologia. 2005, Vol 182, Num 3, pp 414-419, issn 0033-3158, 6 p.Article