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Results 1 to 25 of 44

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The main role of ugt1a9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variantsBERNARD, Olivier; GUILLEMETTE, Chantal.Drug metabolism and disposition. 2004, Vol 32, Num 8, pp 775-778, issn 0090-9556, 4 p.Article

A novel functional polymorphism in the uridine diphosphate- glucuronosyltransferase 2B7 promoter with significant impact on promoter activityDUGUAY, Yannick; BAAR, Cecilie; SKORPEN, Frank et al.Clinical pharmacology and therapeutics. 2004, Vol 75, Num 3, pp 223-233, issn 0009-9236, 11 p.Article

Alternatively Spliced Products of the UGT1A Gene Interact with the Enzymatically Active Proteins to Inhibit Glucuronosyltransferase Activity In VitroBELLEMARE, Judith; ROULEAU, Mélanie; GIRARD, Hugo et al.Drug metabolism and disposition. 2010, Vol 38, Num 10, pp 1785-1789, issn 0090-9556, 5 p.Article

Influence of nonsynonymous polymorphisms of UGT1A8 and UGT2B7 metabolizing enzymes on the formation of phenolic and acyl glucuronides of mycophenolic acidBERNARD, Olivier; TOJCIC, Jelena; JOURNAULT, Kim et al.Drug metabolism and disposition. 2006, Vol 34, Num 9, pp 1539-1545, issn 0090-9556, 7 p.Article

Liquid Chromatography—Coupled Tandem Mass Spectrometry Based Assay to Evaluate Inosine-5'-monophosphate Dehydrogenase Activity in Peripheral Blood Mononuclear Cells from Stem Cell Transplant RecipientsLAVERDIERE, Isabelle; CARON, Patrick; COUTURE, Félix et al.Analytical chemistry (Washington). 2012, Vol 84, Num 1, pp 216-223, issn 0003-2700, 8 p.Article

In Vitro Investigation of Human UDP-Glucuronosyltransferase Isoforms Responsible for Tacrolimus Glucuronidation: Predominant Contribution of UGT1A4LAVERDIERE, Isabelle; CARON, Patrick; HARVEY, Mario et al.Drug metabolism and disposition. 2011, Vol 39, Num 7, pp 1127-1130, issn 0090-9556, 4 p.Article

Regulation of the UGT1A1 bilirubin-conjugating pathway : Role of a new splicing event at the UGT1A locusLEVESQUE, Eric; GIRARD, Hugo; JOURNAULT, Kim et al.Hepatology (Baltimore, Md.). 2007, Vol 45, Num 1, pp 128-138, issn 0270-9139, 11 p.Article

Bioavailability of testosterone enanthate dependent on genetic variation in the phosphodiesterase 7B but not on the uridine 5'-diphospho-glucuronosyltransferase (UGT2B17) geneEKSTRÖM, Lena; SCHULZE, Jenny J; GUILLEMETTE, Chantal et al.Pharmacogenetics and genomics (Print). 2011, Vol 21, Num 6, pp 325-332, issn 1744-6872, 8 p.Article

Sensitive high-performance liquid chromatography-tandem mass spectrometry method for quantitative analysis of mycophenolic acid and its glucuronide metabolites in human plasma and urineBENOIT-BIANCAMANO, Marie-Odile; CARON, Patrick; LDVESQUE, Eric et al.Journal of chromatography. B. 2007, Vol 858, Num 1-2, pp 159-167, issn 1570-0232, 9 p.Article

Correlation Between Circulatory, Local Prostatic, and Intra-Prostatic Androgen LevelsOLSSON, Mats; EKSTRÖ, Lena; GUILLEMETTE, Chantal et al.The Prostate. 2011, Vol 71, Num 9, pp 909-914, issn 0270-4137, 6 p.Article

Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humansBELLEMARE, Judith; ROULEAU, Mélanie; HARVEY, Mario et al.Journal of pathology (Print). 2011, Vol 223, Num 3, pp 425-435, issn 0022-3417, 11 p.Article

Transcriptional diversity at the UGT2B7 locus is dictated by extensive pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variantsMENARD, Vincent; EAP, Olivier; ROBERGE, Joannie et al.Pharmacogenetics and genomics (Print). 2011, Vol 21, Num 10, pp 631-641, issn 1744-6872, 11 p.Article

Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 geneGUILLEMETTE, Chantal; RITTER, Joseph K; AUYEUNG, Diana J et al.Pharmacogenetics (London). 2000, Vol 10, Num 7, pp 629-644, issn 0960-314XArticle

Profiling Endogenous Serum Estrogen and Estrogen-Glucuronides by Liquid Chromatography―Tandem Mass SpectrometryCARON, Patrick; AUDET-WALSH, Etienne; LEPINE, Johanie et al.Analytical chemistry (Washington). 2009, Vol 81, Num 24, pp 10143-10148, issn 0003-2700, 6 p.Article

Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancerGAGNON, Jean-Francois; BERNARD, Olivier; VILLENEUVE, Lyne et al.Clinical cancer research. 2006, Vol 12, Num 6, pp 1850-1858, issn 1078-0432, 9 p.Article

Genetic diversity at the UGT1 locus is amplified by a novel 3' alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activityGIRARD, Hugo; LEVESQUE, Eric; BELLEMARE, Judith et al.Pharmacogenetics and genomics (Print). 2007, Vol 17, Num 12, pp 1077-1089, issn 1744-6872, 13 p.Article

Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer riskZHONG ZHENG; PARK, Jong Y; GUILLEMETTE, Chantal et al.Journal of the National Cancer Institute. 2001, Vol 93, Num 18, pp 1411-1418, issn 0027-8874Article

Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidationLEVESQUE, Eric; MENARD, Vincent; LAVERDIERE, Isabelle et al.Pharmacogenetics and genomics (Print). 2010, Vol 20, Num 3, pp 195-210, issn 1744-6872, 16 p.Article

Deferiprone Glucuronidation by Human Tissues and Recombinant UDP Glucuronosyltransferase 1A6 : An in Vitro Investigation of Genetic and Splice VariantsBENOIT-BIANCAMANO, Marie-Odile; CONNELLY, John; VILLENEUVE, Lyne et al.Drug metabolism and disposition. 2009, Vol 37, Num 2, pp 322-329, issn 0090-9556, 8 p.Article

The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liverGIRARD, Hugo; VILLENEUVE, Lyne; COURT, Michael H et al.Drug metabolism and disposition. 2006, Vol 34, Num 7, pp 1220-1228, issn 0090-9556, 9 p.Article

UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liverGIRARD, Hugo; THIBAUDEAU, Jean; COURT, Michael H et al.Hepatology (Baltimore, Md.). 2005, Vol 42, Num 2, pp 448-457, issn 0270-9139, 10 p.Article

Steroidogenic Germline Polymorphism Predictors of Prostate Cancer Progression in the Estradiol PathwayLEVESQUE, Eric; LAVERDIERE, Isabelle; AUDET-WALSH, Etienne et al.Clinical cancer research (Print). 2014, Vol 20, Num 11, pp 2971-2983, issn 1078-0432, 13 p.Article

Pharmacogenetic Impact of UDP-Glucuronosyltransferase Metabolic Pathway and Multidrug Resistance-Associated Protein 2 Transport Pathway on Mycophenolic Acid in Thoracic Transplant Recipients: An Exploratory StudyTING, Lillian S. L; BENOIT-BIANCAMANO, Marie-Odile; BERNARD, Olivier et al.Pharmacotherapy. 2010, Vol 30, Num 11, pp 1097-1108, issn 0277-0008, 12 p.Article

Association of genetic polymorphisms in UGT1A1 with breast cancer and plasma hormone levelsGUILLEMETTE, Chantal; DE VIVO, Immaculata; HANKINSON, Susan E et al.Cancer epidemiology, biomarkers & prevention. 2001, Vol 10, Num 6, pp 711-714, issn 1055-9965Article

In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver MicrosomesTOJCIC, Jelena; BENOIT-BIANCAMANO, Marie-Odile; COURT, Michael H et al.Drug metabolism and disposition. 2009, Vol 37, Num 11, pp 2236-2243, issn 0090-9556, 8 p.Article

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