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Results 1 to 25 of 41

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The interplay between antiviral activity, oligonucleotide hybridisation and nucleic acids incorporation studiesHERDEWIJN, Piet.Antiviral research. 2006, Vol 71, Num 2-3, pp 317-321, issn 0166-3542, 5 p.Article

Simple approach to 1-O-protected (R)- and (S)-glycerols from L- and D-arabinose for glycerol nucleic acids (GNA) monomers researchDOBOSZEWSKI, Bogdan; HERDEWIJN, Piet.Tetrahedron letters. 2011, Vol 52, Num 30, issn 0040-4039, 3841, 3853-3855 [4 p.]Article

Synthesis of 3'-S-Phosphonomethyl-Modified Nucleoside Phosphonates with a 3'-Deoxy-3'-thio-α-L-threosyl Sugar MoietyQIUYA HUANG; HERDEWIJN, Piet.European journal of organic chemistry (Print). 2011, Num 19, pp 3450-3457, issn 1434-193X, 8 p.Article

2'-Deoxy-2'-α-C-(hydroxymethyl)adenosine as Potential anti-HCV AgentCHAVAIN, Natascha; HERDEWIJN, Piet.European journal of organic chemistry (Print). 2011, Num 6, pp 1140-1147, issn 1434-193X, 8 p.Article

The cyclohexene ring as bioisostere of a furanose ring: Synthesis and antiviral activity of cyclohexenyl nucleosidesHERDEWIJN, Piet; DE CLERCQ, Erik.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 12, pp 1591-1597, issn 0960-894XArticle

Identification of a novel resistance mutation for benzimidazole inhibitors of the HCV RNA-dependent RNA polymeraseDELANG, Leen; FROEYEN, Mathy; HERDEWIJN, Piet et al.Antiviral research. 2012, Vol 93, Num 1, pp 30-38, issn 0166-3542, 9 p.Article

Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processingMAITI, Mohitosh; NAUWELAERTS, Koen; HERDEWIJN, Piet et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 4, pp 1709-1711, issn 0960-894X, 3 p.Article

Stereocontrolled synthesis of ara-type cyclohexenyl nucleosidesJING WANG; VINA, Dolores; BUSSON, Roger et al.Journal of organic chemistry. 2003, Vol 68, Num 11, pp 4499-4505, issn 0022-3263, 7 p.Article

Substrate based peptide aldehyde inhibits bacterial type I signal peptidaseBUZDER-LANTOS, Peter; BOCKSTAEL, Katrijn; ANNE, Jozef et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 10, pp 2880-2883, issn 0960-894X, 4 p.Article

Increased uptake of antisense oligonucleotides by delivery as double stranded complexesASTRIAB-FISHER, Anna; FISHER, Michael H; JULIANO, Rudy et al.Biochemical pharmacology. 2004, Vol 68, Num 3, pp 403-407, issn 0006-2952, 5 p.Article

Comparison of library screening techniques used in the development of dsDNA ligandsCHALTIN, Patrick; BORGIONS, Filip; VAN AERSCHOT, Arthur et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 1, pp 47-50, issn 0960-894X, 4 p.Article

Predicting melting temperature (Tm) of oligoribonucleotide duplex by neural networkLIXIN MA; CHANGMEI CHENG; MIYAJIMA, Hiromi et al.Journal of chemometrics. 2002, Vol 16, Num 2, pp 75-80, issn 0886-9383Article

Pseudouridine detection improvement by derivatization with methyl vinyl sulfone and capillary HPLC-mass spectrometryEMMERECHTS, Gert; HERDEWIJN, Piet; ROZENSKI, Jef et al.Journal of chromatography. B. 2005, Vol 825, Num 2, pp 233-238, issn 1570-0232, 6 p.Article

Synthesis and conformational analysis of 1-[2,4-dideoxy-4-C-hydroxymethyl-α-L-lyxopyranosyl]thymineVANHEUSDEN, Veerle; BUSSON, Roger; HERDEWIJN, Piet et al.Journal of organic chemistry. 2004, Vol 69, Num 13, pp 4446-4453, issn 0022-3263, 8 p.Article

Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines : A new class of pestivirus inhibitorsPUERSTINGER, Gerhard; PAESHUYSE, Jan; HERDEWIJN, Piet et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 20, pp 5345-5349, issn 0960-894X, 5 p.Article

Synthesis and conformational analysis of a ribo-type cyclohexenyl nucleosideVIJGEN, Sara; NAUWELAERTS, Koen; JING WANG et al.Journal of organic chemistry. 2005, Vol 70, Num 12, pp 4591-4597, issn 0022-3263, 7 p.Article

HNA and ANA high-affinity arrays for detections of DNA and RNA single-base mismatchesABRAMOV, Mikhail; SCHEPERS, Guy; VAN AERSCHOT, Arthur et al.Biosensors & bioelectronics. 2008, Vol 23, Num 11, pp 1728-1732, issn 0956-5663, 5 p.Article

Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinaseVANHEUSDEN, Veerle; MUNIER-LEHMANN, Hélène; POCHET, Sylvie et al.Bioorganic & medicinal chemistry letters (Print). 2002, Vol 12, Num 19, pp 2695-2698, issn 0960-894XArticle

Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2'-Fluoro RNASETH, Punit P; JINGHUA YU; JAZAYERI, Ali et al.Journal of organic chemistry. 2012, Vol 77, Num 11, pp 5074-5085, issn 0022-3263, 12 p.Article

Biological effects of hexitol and altritol-modified siRNAs targeting B-RafFISHER, Michael; ABRAMOV, Mikhail; VAN AERSCHOT, Arthur et al.European journal of pharmacology. 2009, Vol 606, Num 1-3, pp 38-44, issn 0014-2999, 7 p.Article

The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replicationPAESHUYSE, Jan; CHEZAL, Jean-Michel; KOENEN, Frank et al.Journal of virology. 2007, Vol 81, Num 20, pp 11046-11053, issn 0022-538X, 8 p.Article

A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerasePAESHUYSE, Jan; LEYSSEN, Pieter; LETELLIER, Carine et al.Journal of virology. 2006, Vol 80, Num 1, pp 149-160, issn 0022-538X, 12 p.Article

Synthetic Genetic Polymers Capable of Heredity and EvolutionPINHEIRO, Vitor B; TAYLOR, Alexander I; HERDEWIJN, Piet et al.Science (Washington, D.C.). 2012, Vol 336, Num 6079, pp 341-344, issn 0036-8075, 4 p.Article

Highly potent and selective inhibition of bovine viral diarrhea virus replication by γ-carboline derivativesSALIM, Mohammed T. A; GOTO, Yukinori; HERDEWIJN, Piet et al.Antiviral research. 2010, Vol 88, Num 3, pp 263-268, issn 0166-3542, 6 p.Article

An easy and fast method for the evaluation of Staphylococcus epidermidis type I signal peptidase inhibitorsBOCKSTAEL, Katrijn; GEUKENS, Nick; SMITHA RAO, C. V et al.Journal of microbiological methods. 2009, Vol 78, Num 2, pp 231-237, issn 0167-7012, 7 p.Article

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