Concise Total Synthesis of (-)-Deoxocuscohygrine and (-)-DihydrocuscohygrineYAMAUCHI, Takayasu; HAGIWARA, Sachi; HIGASHIYAMA, Kimio et al.Journal of organic chemistry. 2008, Vol 73, Num 24, pp 9784-9787, issn 0022-3263, 4 p.Article

Hydroxyethylated cationic cholesterol derivatives in liposome vectors promote gene expression in the lungWUXIAO DING; HATTORI, Yoshiyuki; HIGASHIYAMA, Kimio et al.International journal of pharmaceutics. 2008, Vol 354, Num 1-2, pp 196-203, issn 0378-5173, 8 p.Article

Direct Aldol Reaction of Trifluoromethyl Ketones with Ketones Catalyzed by Et₂Zn and Secondary AminesSASAKI, Shigeru; KIKUCHI, Kasumi; YAMAUCHI, Takayasu et al.Synlett (Stuttgart). 2011, Num 10, pp 1431-1434, issn 0936-5214, 4 p.Article

Efficient microwave-assisted prenylation of pinostrobin and biological evaluation of its derivatives as antitumor agentsPOERWONO, Hadi; SASAKI, Shigeru; HATTORI, Yoshiyuki et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 7, pp 2086-2089, issn 0960-894X, 4 p.Article

Antinociceptive effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in mice: Structure-activity relation study of matrine-type alkaloidsKOBASHI, Seiichi; KUBO, Hajime; YAMAUCHI, Takayasu et al.Biological & pharmaceutical bulletin. 2002, Vol 25, Num 8, pp 1030-1034, issn 0918-6158Article

Brønsted Acid Catalyzed Friedel―Crafts Alkylation Reactions of Trifluoromethyl-α,β-ynones with IndolesSASAKI, Shigeru; IKEKAME, Yuta; TANAYAMA, Manabu et al.Synlett (Stuttgart). 2012, Num 18, pp 2699-2703, issn 0936-5214, 5 p.Article

A combination of liposomal sunitinib plus liposomal irinotecan and liposome co-loaded with two drugs enhanced antitumor activity in PC12-bearing mouseMAITANI, Yoshie; SAITO, Hiroshi; SEISHI, Yuki et al.Journal of drug targeting. 2012, Vol 20, Num 10, pp 873-882, issn 1061-186X, 10 p.Article

P-Dodecylaminophenol derived from the synthetic retinoid, fenretinide : Antitumor efficacy in vitro and in vivo against human prostate cancer and mechanism of actionTAKAHASHI, Noriko; WATANABE, Yusuke; MAITANI, Yoshie et al.International journal of cancer. 2008, Vol 122, Num 3, pp 689-698, issn 0020-7136, 10 p.Article

Lack of development of behavioral sensitization to methylphenidate in mice : Correlation with reversible astrocytic activationSUZUKI, Tsutomu; SHINDO, Keiko; MIYATAKE, Mayumi et al.European journal of pharmacology. 2007, Vol 574, Num 1, pp 39-48, issn 0014-2999, 10 p.Article

Simultaneous optimization based on artificial neural networks in ketoprofen hydrogel formula containing O-ethyl-3-butylcyclohexanol as percutaneous absorption enhancerWU, Pao-Chu; OBATA, Yasuko; FUJIKAWA, Mikito et al.Journal of pharmaceutical sciences. 2001, Vol 90, Num 8, pp 1004-1014, issn 0022-3549Article

Effect of 1-O-ethyl-3-butylcyclohexanol on the skin permeation of drugs with different physicochemical characteristicsLI, Chao Jie; OBATA, Yasuko; HIGASHIYAMA, Kimio et al.International journal of pharmaceutics. 2003, Vol 259, Num 1-2, pp 193-198, issn 0378-5173, 6 p.Article

Promoting mechanism of menthol derivative, 1-O-ethyl-3-buthylcyclohexanol, on the percutaneous absorption of ketoprofenLI, Chao Jie; HIGASHIYAMA, Kimio; YOSHIMURA, Yoshihiro et al.Biological & pharmaceutical bulletin. 2001, Vol 24, Num 9, pp 1044-1048, issn 0918-6158Article

The hypoglycemic effect of (7R*, 9aS*)-7-phenyl-octahydroquinolizin-2-one in miceKUBO, Hajime; KOBAYASHI, Junji; HIGASHIYAMA, Kimio et al.Biological & pharmaceutical bulletin. 2000, Vol 23, Num 9, pp 1114-1117, issn 0918-6158Article

Changes in the rewarding effects induced by tramadol and its active metabolite Ml after sciatic nerve injury in miceNAKAMURA, Atsushi; NARITA, Minoru; MIYOSHI, Kan et al.Psychopharmacologia. 2008, Vol 200, Num 3, pp 307-316, issn 0033-3158, 10 p.Article

Elevation of plasma levels of L-dopa in transdermal administration of L-dopa-butylester in ratsSUDO, Jun-Ichi; IWASE, Hiroaki; HIGASHIYAMA, Kimio et al.Drug development and industrial pharmacy. 2002, Vol 28, Num 1, pp 59-65, issn 0363-9045Article

Evaluation and structure-activity relationship of synthesized cyclohexanol derivatives on percutaneous absorption of ketoprofen using artificial neural networkOBATA, Yasuko; CHAO JIE LI; FUJIKAWA, Mikito et al.International journal of pharmaceutics. 2001, Vol 212, Num 2, pp 223-231, issn 0378-5173Article