A practical preparation of methyl 2-methoxy-6-methylaminopyridine-3-carboxylate from 2,6-dichloro-3-trifluoromethylpyridineHORIKAWA, Tamaki; HIROKAWA, Yoshimi; KATO, Shiro et al.Chemical and pharmaceutical bulletin. 2001, Vol 49, Num 12, pp 1621-1627, issn 0009-2363Article

An efficient synthesis of 5-bromo-2-methoxy-6-methylaminopyridine-3-carboxylic acidHIROKAWA, Yoshimi; HORIKAWA, Tamaki; KATO, Shiro et al.Chemical and pharmaceutical bulletin. 2000, Vol 48, Num 12, pp 1847-1853, issn 0009-2363Article

Synthesis and structure-activity relationships of 4-amino-5-chloro-N-(1,4-dialkylhexahydro-1,4-diazepin-6-yl)-2-methoxybenzamide derivatives, novel and potent serotonin 5-HT₃ and dopamine D₂ receptors dual antagonistHIROKAWA, Yoshimi; HARADA, Hiroshi; YOSHIKAWA, Takashi et al.Chemical and pharmaceutical bulletin. 2002, Vol 50, Num 7, pp 941-959, issn 0009-2363Article

Pleuromutilin derivatives having a purine ring. Part 2: Influence of the central spacer on the antibacterial activity against Gram-positive pathogensHIROKAWA, Yoshimi; KINOSHITA, Hironori; TANAKA, Tomoyuki et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 1, pp 170-174, issn 0960-894X, 5 p.Article

Pleuromutilin derivatives having a purine ring. Part 3: Synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacerHIROKAWA, Yoshimi; KINOSHITA, Hironori; TANAKA, Tomoyuki et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 1, pp 175-179, issn 0960-894X, 5 p.Article

Novel and potent human and rat β₃-Adrenergic receptor agonists containing substituted 3-indolylalkylaminesHARADA, Hiroshi; HIROKAWA, Yoshimi; SUZUKI, Kenji et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 7, pp 1301-1305, issn 0960-894X, 5 p.Article