Antiviral acyclic nucleoside phosphonates structure activity studiesHOLY, Antonin.Antiviral research. 2006, Vol 71, Num 2-3, pp 248-253, issn 0166-3542, 6 p.Article

Phosphonomethoxyalkyl analogs of nucleotidesHOLY, Antonin.Current pharmaceutical design. 2003, Vol 9, Num 31, pp 2567-2592, issn 1381-6128, 26 p.Article

Synthesis of Analogues of Acyclic Nucleoside Diphosphates Containing a (Phosphonomethyl)phosphanyl Moiety and Studies of Their PhosphorylationDOLAKOVA, Petra; DRACINSKY, Martin; FANFRLIK, Jindrich et al.European journal of organic chemistry (Print). 2009, Num 7, pp 1082-1092, issn 1434-193X, 11 p.Article

Syntheses of N³-substituted thymine acyclic nucleoside phosphonates and a comparison of their inhibitory effect towards thymidine phosphorylasePOMEISL, Karel; HOLY, Antonin; VOTRUBA, Ivan et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 4, pp 1364-1367, issn 0960-894X, 4 p.Article

Secretion of antiretroviral chemokines by human cells cultured with acyclic nucleoside phosphonatesZIDEK, Zdenek; KMONICKOVA, Eva; HOLY, Antonin et al.European journal of pharmacology. 2007, Vol 574, Num 1, pp 77-84, issn 0014-2999, 8 p.Article

Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophagesCESNEK, Michal; HOLY, Antonin; MASOJIDKOVA, Milena et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 8, pp 2917-2926, issn 0968-0896, 10 p.Article

Cytostatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytesZIDEK, Zdenek; POTMESIL, Petr; HOLY, Antonin et al.Toxicology and applied pharmacology. 2003, Vol 192, Num 3, pp 246-253, issn 0041-008X, 8 p.Article

Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N⁶-substituted adenines, and 2,6-diaminopurinesZIDEK, Zdenek; POTMESIL, Petr; KMONIEKOVA, Eva et al.European journal of pharmacology. 2003, Vol 475, Num 1-3, pp 149-159, issn 0014-2999, 11 p.Article

Charge density study of hydrogen [(2,4-diaminopyrimidin-1-io)methyl]phosphonate monohydrateSLOUF, Miroslav; HOLY, Antonin; PETRICEK, Vaclav et al.Acta crystallographica. Section B, Structural science. 2002, Vol 58, Num 3, pp 519-529, issn 0108-7681, 2Article

N⁶-Methyl-AMP aminohydrolase activates N⁶-substituted purine acyclic nucleoside phosphonatesSCHINKMANOUD, Markéta; VOTRUBA, Ivan; HOLY, Antonin et al.Biochemical pharmacology. 2006, Vol 71, Num 9, pp 1370-1376, issn 0006-2952, 7 p.Article

Synthesis and Properties of a Novel Type of Acyclic Nucleoside Phosphonates: 2-(Purin-9-yl)ethoxyphenylphosphonic AcidsHOCKOVA, Dana; DRACINSKY, Martin; HOLY, Antonin et al.European journal of organic chemistry (Print). 2010, Num 15, pp 2885-2892, issn 1434-193X, 8 p.Article

Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9-deazapurine and related compoundsOTMAR, Miroslav; MASOJIDKOVA, Milena; VOTRUBA, Ivan et al.Bioorganic & medicinal chemistry. 2004, Vol 12, Num 12, pp 3187-3195, issn 0968-0896, 9 p.Article

Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymesKREJCOVD, Romana; HORSKD, Kvetoslava; VOTRUBA, Ivan et al.Biochemical pharmacology. 2000, Vol 60, Num 12, pp 1907-1913, issn 0006-2952Article

Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 positionKRECMEROVA, Marcela; MASOJIDKOVA, Milena; HOLY, Antonín et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 1, pp 387-395, issn 0968-0896, 9 p.Article

Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylasePOMEISL, Karel; HOLY, Antonín; POHL, Radek et al.Tetrahedron (Oxford. Print). 2009, Vol 65, Num 41, issn 0040-4020, 8442, 8486-8492 [8 p.]Article

Synthesis of guanidino analogues of PMPDAP and their immunobiological activityCESNEK, Michal; HOLY, Antonin; MASOJIDKOVA, Milena et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 2, pp 965-980, issn 0968-0896, 16 p.Article

Nucleotide analogues with immunobiological properties : 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (ΗPMPDAP), and their Ν⁶-substituted derivativesPOTMESIL, Petr; KRECMEROVA, Marcela; KMONICKOVA, Eva et al.European journal of pharmacology. 2006, Vol 540, Num 1-3, pp 191-199, issn 0014-2999, 9 p.Article

Isotopic Exchange of Hydrogen at C-5 in Pyrimidine Derivatives: Tautomers with an sp³-Hybridised C-5 Carbon AtomDRACINSKY, Martin; HOLY, Antonin; JANSA, Petr et al.European journal of organic chemistry (Print). 2009, Num 24, pp 4117-4122, issn 1434-193X, 6 p.Article

Alpha anomer of 5-aza-2-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cellsHDJEK, Miroslau; VOTRUBA, Ivan; HOLY, Antonin et al.Biochemical pharmacology. 2008, Vol 75, Num 4, pp 965-972, issn 0006-2952, 8 p.Article

Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivativesDOLAKOVA, Petra; HOLY, Antonin; ZIDEK, Zdenek et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 7, pp 2349-2354, issn 0968-0896, 6 p.Article

Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in miceBOTROS, Sanaa; WILLIAM, Samia; HAMMAM, Olfat et al.Antimicrobial agents and chemotherapy. 2003, Vol 47, Num 12, pp 3853-3858, issn 0066-4804, 6 p.Article

Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activityHOCKOVA, Dana; HOLY, Antonín; ANDREI, Graciela et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 15, pp 4445-4453, issn 0968-0896, 9 p.Article

Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strainsLEBEAU, Ilya; ANDREI, Graciela; KRECMEROVA, Marcela et al.Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 6, pp 2268-2273, issn 0066-4804, 6 p.Article

The substrate activity of (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine diphosphate toward DNA polymerases α, δ and εBIRKUS, Gabriel; REJMAN, Dominik; OTMAR, Miroslav et al.Antiviral chemistry & chemotherapy. 2004, Vol 15, Num 1, pp 23-33, issn 0956-3202, 11 p.Article

Efficient and 'green' microwave-assisted synthesis of haloalkylphosphonates via the Michaelis―Arbuzov reactionJANSA, Petr; HOLY, Antonin; DRACINSKY, Martin et al.Green chemistry (Print). 2011, Vol 13, Num 4, pp 882-888, issn 1463-9262, 7 p.Article