A new approach to receptor ligand design: synthesis and conformation of a new class of potent and highly selective μ opioid antagonists utilizing tetrahydroisoquinoline carboxylic acidKAZMIERSKI, W; HRUBY, V. J.Tetrahedron (Oxford. Print). 1988, Vol 44, Num 3, pp 697-710, issn 0040-4020Article

Synthesis of cyclic peptides by solid phase methodologyLEBL, M; HRUBY, V. J.Tetrahedron letters. 1984, Vol 25, Num 20, pp 2067-2068, issn 0040-4039Article

Conformational analysis of enkephalin analogs containing a disulfide bond. Models for delta- and mu-receptor opioid agonistsFROIMOWITZ, M; HRUBY, V. J.International journal of peptide & protein research. 1989, Vol 34, Num 2, pp 88-96, issn 0367-8377Article

Prediction of the conformational requirements for binding to the κ-opioid receptor and its subtypes. I: Novel α-helical cyclic peptides and their role in receptor selectivityCOLLINS, N; HRUBY, V. J.Biopolymers. 1994, Vol 34, Num 9, pp 1231-1241, issn 0006-3525Article

Peptide chemistry: design and synthesis of peptides, conformational analysis and biological functionsHRUBY, V. J; SCHWYZER, R.Tetrahedron (Oxford. Print). 1988, Vol 44, Num 3, issn 0040-4020, XI-346 pSerial Issue

Examination of the conformational meaning of δ-address in the dermenkephalin sequenceNIKIFOROVICH, G. V; HRUBY, V. J.Biochemical and biophysical research communications (Print). 1990, Vol 173, Num 2, pp 521-527, issn 0006-291X, 7 p.Article

Isolation and structure elucidation of bovine pineal arginine vasopressin : arginine vasotocin not identifiedBENSON, B; EBELS, I; HRUBY, V. J et al.International journal of peptide & protein research. 1990, Vol 36, Num 2, pp 109-121, issn 0367-8377, 13 p.Article

Conformational and topographical considerations in designing agonist peptidomimetics from peptide leadsHRUBY, V. J; BALSE, P. M.Current medicinal chemistry. 2000, Vol 7, Num 9, pp 945-970, issn 0929-8673Article

New amino acids for the topographical control of peptide conformation : synthesis of all the isomers of α,β-dimethylphenylalanine and α,β-dimethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid of high optical purityKAZMIERSKI, W. M; URBANCZYKLIPKOWSKA, Z; HRUBY, V. J et al.Journal of organic chemistry. 1994, Vol 59, Num 7, pp 1789-1795, issn 0022-3263Article

The absolute configuration of an intermediate in the asymmetric synthesis of unusual amino acidsRAMALINGA DHARANIPRAGADA; BRUCK, M; HRUBY, V. J et al.Acta crystallographica. Section C, Crystal structure communications. 1992, Vol 48, pp 1239-1241, issn 0108-2701, 7Article

A simple general method for (radio)iodination of a phenylalanine residue in peptides : preparation of [D-pen²,4'-¹²⁵I-Phe⁴,D-Pen⁵]enkephalin, a peptide with extraordinary selectivity for δ-opioid receptorsSHARMA, S. D; TOTH, G; HRUBY, V. J et al.Journal of organic chemistry. 1991, Vol 56, Num 16, pp 4981-4983, issn 0022-3263, 3 p.Article

Emerging approaches in the molecualr design of receptor-selective peptide ligands : conformational, topographical and dynamic considerationsHRUBY, V. J; AL-OBEIDI, F; KAZMIERSKI, W et al.Biochemical journal (London. 1906). 1990, Vol 268, Num 2, pp 249-262, issn 0006-2936, 14 p.Article

Tryptophan-containing 1,5-tetrazole dipeptide analogs : synthesis of TrpΨ [CN₄]Nle as a cis amide bond surrogateBOTEJU, L. W; HRUBY, V. J.Tetrahedron letters. 1993, Vol 34, Num 11, pp 1757-1760, issn 0040-4039Article

Asymmetric synthesis of topographically constrained amino acids : synthesis of the optically pure isomers of α,β-dimethyl-phenylalanine and α,β-dimethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acidKAZMIERSKI, W. M; HRUBY, V. J.Tetrahedron letters. 1991, Vol 32, Num 41, pp 5769-5772, issn 0040-4039Article

Recent developments in the design of receptor specific opioid peptidesHRUBY, V. J; GEHRIG, C. A.Medicinal research reviews (Print). 1989, Vol 9, Num 3, pp 343-401, issn 0198-6325Article

Proton n.m.r. spectroscopic evidence for sulfur-aromatic interactions in peptidesLEBL, M; SUGG, E. E; HRUBY, V. J et al.International journal of peptide & protein research. 1987, Vol 29, Num 1, pp 40-45, issn 0367-8377Article

1,2-Asymmetric cis induction and its application to the asymmetric synthesis of precursors of β-branched unusual amino acidsGUIGEN LI; PATEL, D; HRUBY, V. J et al.Tetrahedron letters. 1994, Vol 35, Num 15, issn 0040-4039, 2257, 2301-2304 [5 p.]Article

Improved 2D inverse proton detected C,H correlation NMR techniques for the total assignment of carbon resonances of a highly delta opioid receptor agonist peptideKÖVER, K. E; PRAKASH, O; HRUBY, V. J et al.Magnetic resonance in chemistry. 1993, Vol 31, Num 3, pp 231-237, issn 0749-1581Article

Efficient purging sequence for ¹H-detected heteronuclear shift correlation experimentsKÖVER, K. E; PRAKASH, O; HRUBY, V. J et al.Journal of magnetic resonance. 1992, Vol 99, Num 2, pp 426-432, issn 0022-2364Article

Mechanism of glucagon cholereisis in guinea pigLENZEN, R; HRUBY, V. J; TAVOLONI, N et al.American journal of physiology. Gastrointestinal and liver physiology. 1990, Vol 22, Num 5, pp G736-G744, issn 0193-1857Article

Natriuretic action of neurohypophysial peptides: effects of agonists and antagonists and implication of natriuretic receptorCHAN, W. Y; HRUBY, V. J.The Journal of pharmacology and experimental therapeutics. 1988, Vol 246, Num 2, pp 597-602, issn 0022-3565Article

Cyclic melanotropins. VI: Reverse phase HPLC studiesLEBL, M; CODY, W. L; HRUBY, V. J et al.Journal of liquid chromatography. 1984, Vol 7, Num 6, pp 1195-1210, issn 0148-3919Article

New glucagon analogues with conformational restrictions and altered amphiphilicity : effects on binding, adenylate cyclase and glycogenolytic activitiesHRUBY, V. J; GYSIN, B; TRIVEDI, D et al.Life sciences (1973). 1993, Vol 52, Num 10, pp 845-855, issn 0024-3205Article

Conformational analysis of four β-methylphenylalanine stereoisomers in a bioactive peptide by z-filtered relay NMR spectroscopyKÖVER, K. E; DING JIAO; FANG, S et al.Magnetic resonance in chemistry. 1993, Vol 31, Num 12, pp 1072-1076, issn 0749-1581Article

Efficient method for the total asymmetric synthesis of the isomers of β-methyltyrosineNICOLAS, E; RUSSELL, K. C; KNOLLENBERG, J et al.Journal of organic chemistry. 1993, Vol 58, Num 26, pp 7565-7571, issn 0022-3263Article