Inhibition of extracellular Ca²⁺ entry by YC-1, an activator of soluble guanylyl cyclase, through a cyclic GMP-independent pathway in rat neutrophilsWANG, Jih-Pyang; CHANG, Ling-Chu; HUANG, Li-Jiau et al.Biochemical pharmacology. 2001, Vol 62, Num 6, pp 679-684, issn 0006-2952Article

4-Fluoro-N-butylphenylacetamide (H6) inhibits cell growth via cell-cycle arrest and apoptosis in human cervical cancer cellsLIU, Chung-Hsien; HUANG, Li-Jiau; KUO, Sheng-Chu et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 1, pp 42-48, issn 0968-0896, 7 p.Article

Inhibition of lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 macrophages by a synthetic carbazole, LCY-2-CHOTSAO, Lo-Ti; LEE, Chun-Yann; HUANG, Li-Jiau et al.Biochemical pharmacology. 2002, Vol 63, Num 11, pp 1961-1968, issn 0006-2952Article

Synthesis and anticancer activity of benzyloxybenzaldehyde derivatives against HL-60 cellsLIN, Chin-Fen; YANG, Jai-Sing; CHANG, Chiung-Yun et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 5, pp 1537-1544, issn 0968-0896, 8 p.Article

Benzyloxybenzaldehyde analogues as novel adenylyl cyclase activatorsCHANG, Chiung-Yun; KUO, Sheng-Chu; LIN, Yi-Lee et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 15, pp 1971-1974, issn 0960-894XArticle

Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38YANG, Jai-Sing; HOUR, Mann-Jen; KUO, Sheng-Chu et al.Anticancer research. 2004, Vol 24, Num 3A, pp 1769-1778, issn 0250-7005, 10 p.Article

A phenylacetate derivative, SCK6, inhibits cell proliferation via G₁ cell cycle arrest and apoptosisCHAN, Hsu-Chin; KUO, Sheng-Chu; HUANG, Li-Jiau et al.European journal of pharmacology. 2003, Vol 467, Num 1-3, pp 31-39, issn 0014-2999, 9 p.Article

6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds : Their synthesis, cytotoxicity, and inhibition of tubulin polymerizationHOUR, Mann-Jen; HUANG, Li-Jiau; KUO, Sheng-Chu et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 23, pp 4479-4487, issn 0022-2623Article

(2E) -N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide induces apoptosis and cell cycle arrest in HL-60 cellsCHEN, Chun-Jen; HSU, Mei-Hua; KUO, Sheng-Chu et al.Anticancer research. 2007, Vol 27, Num 1A, pp 343-349, issn 0250-7005, 7 p.Article

Ginger and its bioactive component inhibit enterotoxigenic Escherichia coli heat-labile enterotoxin-lnduced diarrhea in miceCHEN, Jaw-Chyun; HUANG, Li-Jiau; WU, Shih-Lu et al.Journal of agricultural and food chemistry (Print). 2007, Vol 55, Num 21, pp 8390-8397, issn 0021-8561, 8 p.Article

Synthesis of furopyrazole analogs of 1 -benzyl -3 -(5 -hydroxymethyl-2-furyl)indazole (YC-1) as novel anti-leukemia agentsCHOU, Li-Chen; HUANG, Li-Jiau; YANG, Jai-Sing et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 4, pp 1732-1740, issn 0968-0896, 9 p.Article

GEA3162, a nitric oxide-releasing agent, activates non-store-operated Ca²⁺ entry and inhibits store-operated Ca²⁺ entry pathways in neutrophils through thiol oxidationHSU, Mei-Feng; CHEN, Yu-San; HUANG, Li-Jiau et al.European journal of pharmacology. 2006, Vol 535, Num 1-3, pp 43-52, issn 0014-2999, 10 p.Article

The anti-inflammatory carbazole, LCY-2-CHO, inhibits lipopolysaccharide-induced inflammatory mediator expression through inhibition of the p38 mitogen-activated protein kinase signaling pathway in macrophagesHO, Feng-Ming; LAI, Chih-Chang; HUANG, Li-Jiau et al.British journal of pharmacology. 2004, Vol 141, Num 6, pp 1037-1047, issn 0007-1188, 11 p.Article

The blockade of cyclopiazonic acid-induced store-operated Ca²⁺ entry pathway by YC-1 in neutrophilsWANG, Jih-Pyang; CHEN, Yu-San; TSAI, Chi-Ren et al.Biochemical pharmacology. 2004, Vol 68, Num 10, pp 2053-2064, issn 0006-2952, 12 p.Article

CHM-1 induces apoptosis via p38-mediated upregulation of DR5 expression in human ovarian cancer SKOV3 cellsLEE, Jang-Chang; CHOU, Li-Chen; HUANG, Chi-Hung et al.European journal of pharmacology. 2011, Vol 670, Num 1, pp 96-104, issn 0014-2999, 9 p.Article

Synthesis of 1-benzyl-3-(5-hydroxymethyl-2-furyl)selenolo[3,2-c]pyrazole derivatives as new anticancer agentsCHOU, Li-Chen; HUANG, Li-Jiau; HSU, Mei-Hua et al.European journal of medicinal chemistry. 2010, Vol 45, Num 4, pp 1395-1402, issn 0223-5234, 8 p.Article

Synthesis of 1-substituted 3-pyridinylmethylidenylindolin-2-ones and 1-substituted 3-quinolinylmethylidenylindolin-2-ones as the enhancers of ATRA-induced differentiation in HL-60 cellsHUNG, Chi-Ying; HSU, Mei-Hua; HUANG, Li-Jiau et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 8, pp 4222-4232, issn 0968-0896, 11 p.Article

Investigation of the cellular mechanism of inhibition of formyl-methionyl-leucyl-phenylalanine-induced superoxide anion generation in rat neutrophils by 2-benzyloxybenzaldehydeWANG, Jih-Pyang; CHANG, Ling-Chu; LIN, Yi-Lee et al.Biochemical pharmacology. 2003, Vol 65, Num 7, pp 1043-1051, issn 0006-2952, 9 p.Article

Signaling mechanisms of inhibition of phospholipase D activation by CHS-111 in formyl peptide-stimulated neutrophilsCHANG, Ling-Chu; HUANG, Tai-Hung; CHANG, Chi-Sen et al.Biochemical pharmacology. 2011, Vol 81, Num 2, pp 269-278, issn 0006-2952, 10 p.Article

Synthesis and in vitro anticancer activity of 6,7-methylenedioxy (or 5-hydroxy-6-methoxy)-2-(substituted selenophenyl)quinolin-4-one analogsCHEN, Chien-Ting; HSU, Mei-Hua; CHENG, Yung-Yi et al.European journal of medicinal chemistry. 2011, Vol 46, Num 12, pp 6046-6056, issn 0223-5234, 11 p.Article

Inhibition of lipopolysaccharide-stimulated no production by a novel synthetic compound CYL-4d in RAW 264.7 macrophages involving the blockade of MEK4/JNK/AP-1 pathwayLIN, Meng-Wei; TSAO, Lo-Ti; CHANG, Ling-Chu et al.Biochemical pharmacology. 2007, Vol 73, Num 11, pp 1796-1806, issn 0006-2952, 11 p.Article

Activation of phosphoinositide 3-kinase and Src family kinase is required for respiratory burst in rat neutrophils stimulated with artocarpol AKUAN, Yu-Hsiang; LIN, Ruey-Hseng; LIN, Hui-Yi et al.Biochemical pharmacology. 2006, Vol 71, Num 12, pp 1735-1746, issn 0006-2952, 12 p.Article

Distinct effects of N-ethylmaleimide on formyl peptide- and cyclopiazonic acid-induced Ca²⁺ signals through thiol modification in neutrophilsHSU, Mei-Feng; SUN, Shu-Ping; CHEN, Yu-San et al.Biochemical pharmacology. 2005, Vol 70, Num 9, pp 1320-1329, issn 0006-2952, 10 p.Article

Acetogenin and Prenylated Flavonoids from Helminthostachys zeylanica with Inhibitory Activity on Superoxide Generation and Elastase Release by NeutrophilsHUANG, Yuan-Chao; HWANG, Tsong-Long; YANG, Yu-Liang et al.Planta medica. 2010, Vol 76, Num 5, pp 447-453, issn 0032-0943, 7 p.Article

Synthesis and Preclinical Evaluations of 2-(2-Fluorophenyl)-6,7-methylenedioxyquinolin-4-one Monosodium Phosphate (CHM—1—P—Na) as a Potent Antitumor AgentCHOU, Li-Chen; CHEN, Chien-Ting; CHIEN, Du-Shieng et al.Journal of medicinal chemistry (Print). 2010, Vol 53, Num 4, pp 1616-1626, issn 0022-2623, 11 p.Article