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kw.\*:("Inhibiteur de la topoisomérase I")

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Paradoxical effects of ethoxidine, a topoisomerase I inhibitor, in the cellular processes leading to angiogenesis on endothelial cellsCLERE, Nicolas; FAURE, Sébastien; HELESBEUX, Jean-Jacques et al.Carcinogenesis (New York. Print). 2011, Vol 32, Num 3, pp 286-295, issn 0143-3334, 10 p.Article

Topoisomerase 1 Inhibitors and Cancer TherapyMOUKHARSKAYA, Julia; VERSCHRAEGEN, Claire.Hematology/oncology clinics of North America. 2012, Vol 26, Num 3, issn 0889-8588, vii, 507-525 [20 p.]Article

Mechanism of hydrolysis of a novel indolocarbazole topoisomerase I inhibitorBRESLIN, David; SATO, Yuichi; KARKI, Shyam B et al.European journal of pharmaceutical sciences. 2010, Vol 39, Num 5, pp 291-297, issn 0928-0987, 7 p.Article

Old class but new dimethoxy analogue of benzimidazole: a bacterial topoisomerase I inhibitorBANSAL, Sandhya; TAWAR, Urmila; SINGH, Manish et al.International journal of antimicrobial agents (Print). 2010, Vol 35, Num 2, pp 186-190, issn 0924-8579, 5 p.Article

Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitorsXIAOYUN ZHANG; RUBING WANG; LI ZHAO et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 2, pp 1276-1281, issn 0960-894X, 6 p.Article

Development of a Validated Immunofluorescence Assay for yH2AX as a Pharmacodynamic Marker of Topoisomerase I Inhibitor ActivityKINDERS, Robert J; HOLLINGSHEAD, Melinda; TOMASZEWSKI, Joseph et al.Clinical cancer research (Print). 2010, Vol 16, Num 22, pp 5447-5457, issn 1078-0432, 11 p.Article

Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone γ-H2AX as a biomarker of DNA damageASHUTOSH RAO, V; AGAMA, Keli; HOLBECK, Susan et al.Cancer research (Baltimore). 2007, Vol 67, Num 20, pp 9971-9979, issn 0008-5472, 9 p.Article

Effects of green tea compounds on irinotecan metabolismMIRKOV, Snezana; KOMOROSKI, Bernard J; RAMIREZ, Jacqueline et al.Drug metabolism and disposition. 2007, Vol 35, Num 2, pp 228-233, issn 0090-9556, 6 p.Article

Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles In vitro and In vivoMIN HUANG; HEYONG GAO; LIPING LIN et al.Clinical cancer research. 2007, Vol 13, Num 4, pp 1298-1307, issn 1078-0432, 10 p.Article

A novel method to load topotecan into liposomes driven by a transmembrane NH4EDTA gradientYUEHUI YANG; YANLING MA; SHAONING WANG et al.European journal of pharmaceutics and biopharmaceutics. 2012, Vol 80, Num 2, pp 332-339, issn 0939-6411, 8 p.Article

Genz-644282, a Novel Non-Camptothecin Topoisomerase I Inhibitor for Cancer TreatmentKURTZBERG, Leslie S; ROTH, Stephanie; FEI WANG et al.Clinical cancer research (Print). 2011, Vol 17, Num 9, pp 2777-2787, issn 1078-0432, 11 p.Article

Pharmacogenetic Pathway Analysis of IrinotecanROSNER, G. L; PANETTA, J. C; INNOCENTI, F et al.Clinical pharmacology and therapeutics. 2008, Vol 84, Num 3, pp 393-402, issn 0009-9236, 10 p.Article

Potential Oral Delivery of 7-Ethyl-10-Hydroxy-Camptothecin (SN-38) using Poly (amidoamine) DendrimersKOLHATKAR, Rohit B; SWAAN, Peter; GHANDEHARI, Hamidreza et al.Pharmaceutical research. 2008, Vol 25, Num 7, pp 1723-1729, issn 0724-8741, 7 p.Article

Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951fSHIOSE, Yoshinobu; KUGA, Hiroshi; YAMASHITA, Fumiyoshi et al.Journal of pharmaceutical and biomedical analysis. 2007, Vol 43, Num 4, pp 1290-1296, issn 0731-7085, 7 p.Article

Topotecan central nervous system penetration is altered by a tyrosine kinase inhibitorYANLI ZHUANG; FRAGA, Charles H; HUBBARD, K. Elaine et al.Cancer research (Baltimore). 2006, Vol 66, Num 23, pp 11305-11313, issn 0008-5472, 9 p.Article

Nonclinical pharmacokinetics and activity of etirinotecan pegol (NKTR-102), a long-acting topoisomerase 1 inhibitor, in multiple cancer modelsHOCH, Ute; STASCHEN, Carl-Michael; JOHNSON, Randall K et al.Cancer chemotherapy and pharmacology. 2014, Vol 74, Num 6, pp 1125-1137, issn 0344-5704, 13 p.Article

Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activitiesSINGH, SheoB; GOETZ, Michael A; DORSO, Karen et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 23, pp 7127-7130, issn 0960-894X, 4 p.Article

Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effectsSAPRA, Puja; KRAFT, Patricia; PASTORINO, Fabio et al.Angiogenesis (London). 2011, Vol 14, Num 3, pp 245-253, issn 0969-6970, 9 p.Article

Preparation and antitumor study of camptothecin nanocrystalsHUA ZHANG; HOLLIS, Christin P; QIANG ZHANG et al.International journal of pharmaceutics (Print). 2011, Vol 415, Num 1-2, pp 293-300, issn 0378-5173, 8 p.Article

A specific transcriptional response of yeast cells to camptothecin dependent on the Swi4 and Mbpl factorsLOTITO, Luca; RUSSO, Alessandra; BUENO, Susana et al.European journal of pharmacology. 2009, Vol 603, Num 1-3, pp 29-36, issn 0014-2999, 8 p.Article

Next generation topoisomerase I inhibitors : Rationale and biomarker strategiesTEICHER, Beverly A.Biochemical pharmacology. 2008, Vol 75, Num 6, pp 1262-1271, issn 0006-2952, 10 p.Article

Cigarette smoking and irinotecan treatment : Pharmacokinetic interaction and effects on neutropeniaVAN DER BOL, Jessica M; MATHIJSSEN, Ron H. J; LOOS, Walter J et al.Journal of clinical oncology. 2007, Vol 25, Num 19, pp 2719-2726, issn 0732-183X, 8 p.Article

Irinotecan-induced diarrhea : Functional significance of the polymorphic ABCC2 transporter proteinDE JONG, F. A; SCOTT-HORTON, T. J; KROETZ, D. L et al.Clinical pharmacology and therapeutics. 2007, Vol 81, Num 1, pp 42-49, issn 0009-9236, 8 p.Article

What are determining factors for stable drug incorporation into polymeric micelle carriers? Consideration on physical and chemical characters of the micelle inner coreYAMAMOTO, Tatsuhiro; YOKOYAMA, Masayuki; OPANASOPIT, Praneet et al.Journal of controlled release. 2007, Vol 123, Num 1, pp 11-18, issn 0168-3659, 8 p.Article

Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776HOLLERAN, Julianne L; PARISE, Robert A; YELLOW-DUKE, Archibong E et al.Journal of pharmaceutical and biomedical analysis. 2010, Vol 52, Num 5, pp 714-720, issn 0731-7085, 7 p.Article

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