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au.\*:("JANSEN, Gerrit")

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Proteasome inhibitors in acute leukemiaNIEWERTH, Denise; DINGJAN, Ilse; CLOOS, Jacqueline et al.Expert review of anticancer therapy. 2013, Vol 13, Num 3, pp 327-337, issn 1473-7140, 11 p.Article

A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migrationVAN DE VEN, Rieneke; SCHEFFER, George L; SCHEPER, Rik J et al.Blood. 2008, Vol 112, Num 6, pp 2353-2359, issn 0006-4971, 7 p.Article

ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolatesSHAFRAN, Assaf; IFERGAN, Ilan; BRAM, Eran et al.Cancer research (Baltimore). 2005, Vol 65, Num 18, pp 8414-8422, issn 0008-5472, 9 p.Article

Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1)HOOIJBERG, Jan Hendrik; JANSEN, Gerrit; ASSARAF, Yehuda G et al.Biochemical pharmacology. 2004, Vol 67, Num 8, pp 1541-1548, issn 0006-2952, 8 p.Article

Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1)HOOIJBERG, Jan Hendrik; JANSEN, Gerrit; KATHMANN, Ietje et al.Cancer chemotherapy and pharmacology. 2014, Vol 73, Num 5, pp 911-917, issn 0344-5704, 7 p.Article

ABCB1 and ABCC3 Gene Polymorphisms Are Associated with First-year Response to Methotrexate in Juvenile Idiopathic ArthritisDE ROTTE, Maurits C. F. J; BULATOVIC, Maja; HEIJSTEK, Marloes W et al.Journal of rheumatology. 2012, Vol 39, Num 10, pp 2032-2040, issn 0315-162X, 9 p.Article

Involvement of Breast Cancer Resistance Protein Expression on Rheumatoid Arthritis Synovial Tissue Macrophages in Resistance to Methotrexate and LeflunomideVAN DER HEIJDEN, Joost W; OERLEMANS, Ruud; JANSEN, Gerrit et al.Arthritis and rheumatism. 2009, Vol 60, Num 3, pp 669-677, issn 0004-3591, 9 p.Article

The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolatesWIELINGA, Peter; HOOIJBERG, Jan Hendrik; WIJNHOLDS, Jan et al.Cancer research (Baltimore). 2005, Vol 65, Num 10, pp 4425-4430, issn 0008-5472, 6 p.Article

Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpressionSIGMOND, Jennifer; BACKUS, Harold H. J; WOUTERS, Dorine et al.Biochemical pharmacology. 2003, Vol 66, Num 3, pp 431-438, issn 0006-2952, 8 p.Article

Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1JING FANG; RHYASEN, Garrett; CORTELEZZI, Agostino et al.Blood. 2012, Vol 120, Num 4, pp 858-867, issn 0006-4971, 10 p.Article

Effect of Noncompetitive Proteasome Inhibition on Bortezomib ResistanceXIAOMING LI; WOOD, Tabitha E; ZHI HUA LI et al.Journal of the National Cancer Institute. 2010, Vol 102, Num 14, pp 1069-1082, issn 0027-8874, 14 p.Article

Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemiaDE JONGE, Robert; TISSING, Wim J. E; HOOIJBERG, Jan Hendrik et al.Blood. 2009, Vol 113, Num 10, pp 2284-2289, issn 0006-4971, 6 p.Article

Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasisMAURITZ, Robert; PETERS, Godefridus J; PINEDO, Herbert M et al.Biochemical pharmacology. 2002, Vol 63, Num 2, pp 105-115, issn 0006-2952Article

Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancerDE WILT, Leonie H. A. M; JANSEN, Gerrit; ASSARAF, Yehuda G et al.Biochemical pharmacology. 2012, Vol 83, Num 2, pp 207-217, issn 0006-2952, 11 p.Article

Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug ResistanceGOTINK, Kristy J; BROXTERMAN, Henk J; GRIFFIOEN, Arjan W et al.Clinical cancer research (Print). 2011, Vol 17, Num 23, pp 7337-7346, issn 1078-0432, 10 p.Article

Folate Receptor β as a Potential Delivery Route for Novel Folate Antagonists to Macrophages in the Synovial Tissue of Rheumatoid Arthritis PatientsVAN DER HEIJDEN, Joost W; OERLEMANS, Ruud; JANSEN, Gerrit et al.Arthritis and rheumatism. 2009, Vol 60, Num 1, pp 12-21, issn 0004-3591, 10 p.Article

Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compoundsLEMOS, Clara; PETERS, Godefridus J; JANSEN, Gerrit et al.European journal of nutrition (Print). 2007, Vol 46, Num 6, pp 329-336, issn 1436-6207, 8 p.Article

Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles : transcriptional silencing, inactivating mutations, and allele lossKAUFMAN, Yotam; IFERGAN, Ilan; ROTHEM, Lilah et al.Blood. 2006, Vol 107, Num 8, pp 3288-3294, issn 0006-4971, 7 p.Article

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasisHOOIJBERG, Jan Hendrik; PETERS, Godefridus J; ASSARAF, Yehuda G et al.Biochemical pharmacology. 2003, Vol 65, Num 5, pp 765-771, issn 0006-2952, 7 p.Article

Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitorsVAN DER WILT, Clasina L; BACKUS, Harold H. J; JACKMAN, Ann L et al.Cancer research (Baltimore). 2001, Vol 61, Num 9, pp 3675-3681, issn 0008-5472Conference Paper

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